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Adverse drug reactions (ADRs) are unwanted or harmful effects experienced after the administration of a certain drug or a combination of drugs, presenting a challenge for drug development and drug administration. In this paper, we present a…

Computation and Language · Computer Science 2019-05-29 Maksim Belousov , Nikola Milosevic , William Dixon , Goran Nenadic

The automation of adverse drug reaction (ADR) detection in social media would revolutionize the practice of pharmacovigilance, supporting drug regulators, the pharmaceutical industry and the general public in ensuring the safety of the…

Computation and Language · Computer Science 2020-05-15 Amy Breden , Lee Moore

Adverse drug reactions / events (ADR/ADE) have a major impact on patient health and health care costs. Detecting ADR's as early as possible and sharing them with regulators, pharma companies, and healthcare providers can prevent morbidity…

Computation and Language · Computer Science 2022-01-07 Hasham Ul Haq , Veysel Kocaman , David Talby

Adverse drug events (ADEs) are an important aspect of drug safety. Various texts such as biomedical literature, drug reviews, and user posts on social media and medical forums contain a wealth of information about ADEs. Recent studies have…

Computation and Language · Computer Science 2024-05-21 Shaoxiong Ji , Ya Gao , Pekka Marttinen

Social media is an useful platform to share health-related information due to its vast reach. This makes it a good candidate for public-health monitoring tasks, specifically for pharmacovigilance. We study the problem of extraction of…

Information Retrieval · Computer Science 2017-09-07 Shashank Gupta , Sachin Pawar , Nitin Ramrakhiyani , Girish Palshikar , Vasudeva Varma

Monitoring the biomedical literature for cases of Adverse Drug Reactions (ADRs) is a critically important and time consuming task in pharmacovigilance. The development of computer assisted approaches to aid this process in different forms…

Computation and Language · Computer Science 2018-04-25 Diego Saldana Miranda

Adverse drug reactions (ADRs) are one of the leading causes of mortality in health care. Current ADR surveillance systems are often associated with a substantial time lag before such events are officially published. On the other hand,…

Information Retrieval · Computer Science 2018-02-15 Shashank Gupta , Manish Gupta , Vasudeva Varma , Sachin Pawar , Nitin Ramrakhiyani , Girish K. Palshikar

Adverse drug reactions (ADRs) are one of the leading causes of mortality in health care. Current ADR surveillance systems are often associated with a substantial time lag before such events are officially published. On the other hand,…

Information Retrieval · Computer Science 2018-02-15 Shashank Gupta , Manish Gupta , Vasudeva Varma , Sachin Pawar , Nitin Ramrakhiyani , Girish K. Palshikar

Post--marketing pharmacovigilance is essential for identifying adverse drug reactions (ADRs) that elude detection during pre--marketing clinical trials. This study explores a novel approach that integrates an adverse event (AE) ontology…

Adverse reaction caused by drugs is a potentially dangerous problem which may lead to mortality and morbidity in patients. Adverse Drug Event (ADE) extraction is a significant problem in biomedical research. We model ADE extraction as a…

Computation and Language · Computer Science 2018-01-03 Suriyadeepan Ramamoorthy , Selvakumar Murugan

An adverse drug effect (ADE) is any harmful event resulting from medical drug treatment. Despite their importance, ADEs are often under-reported in official channels. Some research has therefore turned to detecting discussions of ADEs in…

Computation and Language · Computer Science 2024-07-03 Dorothea MacPhail , David Harbecke , Lisa Raithel , Sebastian Möller

With the advancements in Artificial intelligence (AI) and the accumulation of healthrelated big data, it has become increasingly feasible and commonplace to leverage machine learning technologies to analyze clinical and omics metadata to…

Genomics · Quantitative Biology 2022-04-14 Attayeb Mohsen , Lokesh P. Tripathi , Kenji Mizuguchi

Adverse Drug Event (ADE) extraction models can rapidly examine large collections of social media texts, detecting mentions of drug-related adverse reactions and trigger medical investigations. However, despite the recent advances in NLP, it…

Computation and Language · Computer Science 2021-09-27 Simone Scaboro , Beatrice Portelli , Emmanuele Chersoni , Enrico Santus , Giuseppe Serra

Adverse drug reactions (ADRs) are big concern for public health. ADRs are one of most common causes to withdraw some drugs from markets. Now two major methods for detecting ADRs are spontaneous reporting system (SRS), and prescription event…

Computational Engineering, Finance, and Science · Computer Science 2013-09-02 Yihui Liu , Uwe Aickelin

In this paper, we focus on the classification of tweets as sources of potential signals for adverse drug effects (ADEs) or drug reactions (ADRs). Following the intuition that text and drug structure representations are complementary, we…

Quantitative Methods · Quantitative Biology 2023-11-21 Andrey Sakhovskiy , Elena Tutubalina

In the last decade, an increasing number of users have started reporting Adverse Drug Events (ADE) on social media platforms, blogs, and health forums. Given the large volume of reports, pharmacovigilance has focused on ways to use Natural…

Computation and Language · Computer Science 2022-09-08 Simone Scaboro , Beatrice Portelli , Emmanuele Chersoni , Enrico Santus , Giuseppe Serra

Social media has grown to be a crucial information source for pharmacovigilance studies where an increasing number of people post adverse reactions to medical drugs that are previously unreported. Aiming to effectively monitor various…

Machine Learning · Computer Science 2018-02-19 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu

This paper explores whether the use of drug reviews and social media could be leveraged as potential alternative sources for pharmacovigilance of adverse drug reactions (ADRs). We examined the performance of BERT alongside two variants that…

Computation and Language · Computer Science 2020-04-21 Brent Biseda , Katie Mo

Adverse Drug Reaction (ADR) is a significant public health concern world-wide. Numerous graph-based methods have been applied to biomedical graphs for predicting ADRs in pre-marketing phases. ADR detection in post-market surveillance is no…

Machine Learning · Computer Science 2020-04-02 Heeyoung Kwak , Minwoo Lee , Seunghyun Yoon , Jooyoung Chang , Sangmin Park , Kyomin Jung

Adverse drug reactions (ADR) are widely concerning for public health issue. In this study we propose an original approach to detect ADRs using a feature matrix and feature selection. The experiments are carried out on the drug Simvastatin.…

Computational Engineering, Finance, and Science · Computer Science 2014-09-04 Yihui Liu , Uwe Aickelin
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