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A major obstacle to the integration of deep learning models for chest x-ray interpretation into clinical settings is the lack of understanding of their failure modes. In this work, we first investigate whether there are patient subgroups…

Computer Vision and Pattern Recognition · Computer Science 2021-07-21 Emma Chen , Andy Kim , Rayan Krishnan , Jin Long , Andrew Y. Ng , Pranav Rajpurkar

Objective. This paper presents an overview of generalizable and explainable artificial intelligence (XAI) in deep learning (DL) for medical imaging, aimed at addressing the urgent need for transparency and explainability in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Ahmad Chaddad , Yan Hu , Yihang Wu , Binbin Wen , Reem Kateb

We consider the problem of abnormality localization for clinical applications. While deep learning has driven much recent progress in medical imaging, many clinical challenges are not fully addressed, limiting its broader usage. While…

Computer Vision and Pattern Recognition · Computer Science 2021-12-24 Xi Ouyang , Srikrishna Karanam , Ziyan Wu , Terrence Chen , Jiayu Huo , Xiang Sean Zhou , Qian Wang , Jie-Zhi Cheng

The success of deep convolutional neural networks on image classification and recognition tasks has led to new applications in very diversified contexts, including the field of medical imaging. In this paper we investigate and propose…

Computer Vision and Pattern Recognition · Computer Science 2018-02-14 Alexey A. Novikov , Dimitrios Lenis , David Major , Jiri Hladůvka , Maria Wimmer , Katja Bühler

The interpretation of medical images is a challenging task, often complicated by the presence of artifacts, occlusions, limited contrast and more. Most notable is the case of chest radiography, where there is a high inter-rater variability…

Recent artificial intelligence (AI) algorithms have achieved radiologist-level performance on various medical classification tasks. However, only a few studies addressed the localization of abnormal findings from CXR scans, which is…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Hieu H. Pham , Ha Q. Nguyen , Hieu T. Nguyen , Linh T. Le , Lam Khanh

Automated skin lesion classification using deep learning has shown remarkable accuracy, yet clinical adoption remains limited due to the "black box" nature of these models. We present MelanomaNet, an explainable deep learning system for…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Sukhrobbek Ilyosbekov

Medical image analysis often faces significant challenges due to limited expert-annotated data, hindering both model generalization and clinical adoption. We propose an expert-guided explainable few-shot learning framework that integrates…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Ifrat Ikhtear Uddin , Longwei Wang , KC Santosh

We are concerned with the challenge of reliably classifying and assessing intracranial aneurysms using deep learning without compromising clinical transparency. While traditional black-box models achieve high predictive accuracy, their lack…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Toqa Khaled , Ahmad Al-Kabbany

Most deep learning algorithms lack explanations for their predictions, which limits their deployment in clinical practice. Approaches to improve explainability, especially in medical imaging, have often been shown to convey limited…

Computer Vision and Pattern Recognition · Computer Science 2022-07-12 Maxime Kayser , Cornelius Emde , Oana-Maria Camburu , Guy Parsons , Bartlomiej Papiez , Thomas Lukasiewicz

When encountering a dubious diagnostic case, medical instance retrieval can help radiologists make evidence-based diagnoses by finding images containing instances similar to a query case from a large image database. The similarity between…

Information Retrieval · Computer Science 2021-05-20 Jiansheng Fang , Huazhu Fu , Dan Zeng , Xiao Yan , Yuguang Yan , Jiang Liu

Accurate medical image segmentation is essential for diagnosis and treatment planning of diseases. Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they are…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Ran Gu , Guotai Wang , Tao Song , Rui Huang , Michael Aertsen , Jan Deprest , Sébastien Ourselin , Tom Vercauteren , Shaoting Zhang

Computer-aided diagnosis for low-dose computed tomography (CT) based on deep learning has recently attracted attention as a first-line automatic testing tool because of its high accuracy and low radiation exposure. However, existing methods…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Kyung-Su Kim , Seong Je Oh , Ju Hwan Lee , Myung Jin Chung

Efficient and accurate multi-organ segmentation from abdominal CT volumes is a fundamental challenge in medical image analysis. Existing 3D segmentation approaches are computationally and memory intensive, often processing entire volumes…

Image and Video Processing · Electrical Eng. & Systems 2025-05-19 Hania Ghouse , Muzammil Behzad

Medical images commonly exhibit multiple abnormalities. Predicting them requires multi-class classifiers whose training and desired reliable performance can be affected by a combination of factors, such as, dataset size, data source,…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Sivaramakrishnan Rajaraman , Ghada Zamzmi , Sameer Antani

Chest X-rays play a pivotal role in diagnosing respiratory diseases such as pneumonia, tuberculosis, and COVID-19, which are prevalent and present unique diagnostic challenges due to overlapping visual features and variability in image…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Yiming Lei , Michael Nguyen , Tzu Chia Liu , Hyounkyun Oh

Automated segmentation of anatomical sub-regions with high precision has become a necessity to enable the quantification and characterization of cells/ tissues in histology images. Currently, a machine learning model to analyze…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Hosein Barzekar , Hai Ngu , Han Hui Lin , Mohsen Hejrati , Steven Ray Valdespino , Sarah Chu , Baris Bingol , Somaye Hashemifar , Soumitra Ghosh

Computer-aided techniques may lead to more accurate and more acces-sible diagnosis of thorax diseases on chest radiography. Despite the success of deep learning-based solutions, this task remains a major challenge in smart healthcare, since…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Hongyu Wang , Yong Xia

In response to the worldwide COVID-19 pandemic, advanced automated technologies have emerged as valuable tools to aid healthcare professionals in managing an increased workload by improving radiology report generation and prognostic…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Zhusi Zhong , Jie Li , John Sollee , Scott Collins , Harrison Bai , Paul Zhang , Terrence Healey , Michael Atalay , Xinbo Gao , Zhicheng Jiao

Automated diagnosis using deep neural networks in chest radiography can help radiologists detect life-threatening diseases. However, existing methods only provide predictions without accurate explanations, undermining the trustworthiness of…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Eunji Kim , Siwon Kim , Minji Seo , Sungroh Yoon