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Related papers: From Kepler to Newton: Explainable AI for Science

200 papers

Large language models are a form of artificial intelligence systems whose primary knowledge consists of the statistical patterns, semantic relationships, and syntactical structures of language1. Despite their limited forms of "knowledge",…

Artificial Intelligence · Computer Science 2023-10-13 Yizhen Zheng , Huan Yee Koh , Jiaxin Ju , Anh T. N. Nguyen , Lauren T. May , Geoffrey I. Webb , Shirui Pan

While a vast collection of explainable AI (XAI) algorithms have been developed in recent years, they are often criticized for significant gaps with how humans produce and consume explanations. As a result, current XAI techniques are often…

Artificial Intelligence · Computer Science 2023-08-08 Vivian Lai , Yiming Zhang , Chacha Chen , Q. Vera Liao , Chenhao Tan

Explaining deep learning models is essential for clinical integration of medical image analysis systems. A good explanation highlights if a model depends on spurious features that undermines generalization and harms a subset of patients or,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Yoni Schirris , Eric Marcus , Jonas Teuwen , Hugo Horlings , Efstratios Gavves

Generative AI (GAI) reveals an irreducible human core at the center of data science: advances in GAI should sharpen, rather than diminish, the focus on human reasoning in data science education. GAI can now execute many routine data science…

Computers and Society · Computer Science 2026-04-03 Nathan Taback

The use of wearables in medicine and wellness, enabled by AI-based models, offers tremendous potential for real-time monitoring and interpretable event detection. Explainable AI (XAI) is required to assess what models have learned and build…

Signal Processing · Electrical Eng. & Systems 2026-03-16 Maurice Kuschel , Solveig Vieluf , Claus Reinsberger , Tobias Loddenkemper , Tanuj Hasija

This paper establishes a theoretical foundation for understanding the fundamental limits of AI explainability through algorithmic information theory. We formalize explainability as the approximation of complex models by simpler ones,…

Artificial Intelligence · Computer Science 2025-11-04 Shrisha Rao

Large-scale AI models such as GPT-4 have accelerated the deployment of artificial intelligence across critical domains including law, healthcare, and finance, raising urgent questions about trust and transparency. This study investigates…

Artificial Intelligence · Computer Science 2025-10-20 Allen Daniel Sunny

Recent advancements in machine learning have emphasized the need for transparency in model predictions, particularly as interpretability diminishes when using increasingly complex architectures. In this paper, we propose leveraging…

Machine Learning · Computer Science 2025-07-18 Chenrui Zhu , Louenas Bounia , Vu Linh Nguyen , Sébastien Destercke , Arthur Hoarau

In a post-ChatGPT world, this paper explores the potential of leveraging scalable artificial intelligence for scientific discovery. We propose that scaling up artificial intelligence on high-performance computing platforms is essential to…

Machine Learning · Computer Science 2024-06-27 Wesley Brewer , Aditya Kashi , Sajal Dash , Aristeidis Tsaris , Junqi Yin , Mallikarjun Shankar , Feiyi Wang

The frameworks that explore scientific and technological evolution suggest that discoveries and inventions are intrinsic processes, while the wealth of knowledge accumulated over time enables researchers to make further advancements,…

Physics and Society · Physics 2024-12-30 Youwei He , Jeong-Dong Lee , Seungmin Lee

One of the grand challenges of artificial general intelligence is developing agents capable of conducting scientific research and discovering new knowledge. While frontier models have already been used as aides to human scientists, e.g. for…

Artificial Intelligence · Computer Science 2024-09-04 Chris Lu , Cong Lu , Robert Tjarko Lange , Jakob Foerster , Jeff Clune , David Ha

Artificial intelligence (AI) is reshaping how research is conceived, conducted, and communicated across fields from chemistry to biomedicine. This commentary examines how AI is transforming the research workflow. AI systems now help…

Artificial Intelligence · Computer Science 2025-11-14 Maksim E. Eren , Dorianis M. Perez

The field of AI research is advancing at an unprecedented pace, enabling automated hypothesis generation and experimental design across diverse domains such as biology, mathematics, and artificial intelligence. Despite these advancements,…

Machine Learning · Computer Science 2025-10-07 Yaowenqi Liu , Bingxu Meng , Rui Pan , Yuxing Liu , Jerry Huang , Jiaxuan You , Tong Zhang

In recent years, machine learning (ML) has become a key enabling technology for the sciences and industry. Especially through improvements in methodology, the availability of large databases and increased computational power, today's ML…

Artificial Intelligence · Computer Science 2019-09-27 Wojciech Samek , Klaus-Robert Müller

Mechanistic Interpretability (MI) aims to understand neural networks through causal explanations. Though MI has many explanation-generating methods, progress has been limited by the lack of a universal approach to evaluating explanations.…

Machine Learning · Computer Science 2025-05-05 Kola Ayonrinde , Louis Jaburi

Machine learning has emerged as a powerful tool for scientific discovery, enabling researchers to extract meaningful insights from complex datasets. For instance, it has facilitated the identification of disease-predictive genes from gene…

The rapid growth of scientific literature imposes significant challenges for researchers endeavoring to stay updated with the latest advancements in their fields and delve into new areas. We introduce OpenResearcher, an innovative platform…

This is an integrative review that address the question, "What makes for a good explanation?" with reference to AI systems. Pertinent literatures are vast. Thus, this review is necessarily selective. That said, most of the key concepts and…

Artificial Intelligence · Computer Science 2019-02-07 Shane T. Mueller , Robert R. Hoffman , William Clancey , Abigail Emrey , Gary Klein

Interpretability is the study of explaining models in understandable terms to humans. At present, interpretability is divided into two paradigms: the intrinsic paradigm, which believes that only models designed to be explained can be…

Machine Learning · Computer Science 2024-11-14 Andreas Madsen , Himabindu Lakkaraju , Siva Reddy , Sarath Chandar

Explainable Artificial Intelligence (XAI) is increasingly required in computational economics, where machine-learning forecasters can outperform classical econometric models but remain difficult to audit and use for policy. This survey…

General Economics · Economics 2025-12-16 Agustín García-García , Pablo Hidalgo , Julio E. Sandubete