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Reliability in cell type annotation is challenging in single-cell RNA-sequencing data analysis because both expert-driven and automated methods can be biased or constrained by their training data, especially for novel or rare cell types.…

Quantitative Methods · Quantitative Biology 2024-09-25 Wenjin Ye , Yuanchen Ma , Junkai Xiang , Hongjie Liang , Tao Wang , Qiuling Xiang , Andy Peng Xiang , Wu Song , Weiqiang Li , Weijun Huang

We propose a meta-learning method for learning from multiple noisy annotators. In many applications such as crowdsourcing services, labels for supervised learning are given by multiple annotators. Since the annotators have different skills…

Machine Learning · Computer Science 2025-06-13 Atsutoshi Kumagai , Tomoharu Iwata , Taishi Nishiyama , Yasutoshi Ida , Yasuhiro Fujiwara

Deep ConvNets have shown great performance for single-label image classification (e.g. ImageNet), but it is necessary to move beyond the single-label classification task because pictures of everyday life are inherently multi-label.…

Computer Vision and Pattern Recognition · Computer Science 2019-02-27 Thibaut Durand , Nazanin Mehrasa , Greg Mori

As research interests in medical image analysis become increasingly fine-grained, the cost for extensive annotation also rises. One feasible way to reduce the cost is to annotate with coarse-grained superclass labels while using limited…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Linrui Dai , Wenhui Lei , Xiaofan Zhang

Multi-label classification is a common challenge in various machine learning applications, where a single data instance can be associated with multiple classes simultaneously. The current paper proposes a novel tree-based method for…

Methodology · Statistics 2024-05-01 Chhavi Tyagi , Wenge Guo

When constructing models that learn from noisy labels produced by multiple annotators, it is important to accurately estimate the reliability of annotators. Annotators may provide labels of inconsistent quality due to their varying…

Computation and Language · Computer Science 2019-05-14 Maolin Li , Arvid Fahlström Myrman , Tingting Mu , Sophia Ananiadou

Extreme multi-label classification aims to learn a classifier that annotates an instance with a relevant subset of labels from an extremely large label set. Many existing solutions embed the label matrix to a low-dimensional linear…

Machine Learning · Computer Science 2018-11-06 Yuefeng Liang , Cho-Jui Hsieh , Thomas C. M. Lee

The major challenge of learning from multi-label data has arisen from the overwhelming size of label space which makes this problem NP-hard. This problem can be alleviated by gradually involving easy to hard tags into the learning process.…

Machine Learning · Computer Science 2019-10-09 Seyed Amjad Seyedi , S. Siamak Ghodsi , Fardin Akhlaghian , Mahdi Jalili , Parham Moradi

Predicting all applicable labels for a given image is known as multi-label classification. Compared to the standard multi-class case (where each image has only one label), it is considerably more challenging to annotate training data for…

Computer Vision and Pattern Recognition · Computer Science 2021-10-25 Elijah Cole , Oisin Mac Aodha , Titouan Lorieul , Pietro Perona , Dan Morris , Nebojsa Jojic

In real-world applications, as data availability increases, obtaining labeled data for machine learning (ML) projects remains challenging due to the high costs and intensive efforts required for data annotation. Many ML projects,…

Machine Learning · Computer Science 2024-12-24 Ismail Hakki Karaman , Gulser Koksal , Levent Eriskin , Salih Salihoglu

Learning algorithms normally assume that there is at most one annotation or label per data point. However, in some scenarios, such as medical diagnosis and on-line collaboration,multiple annotations may be available. In either case,…

Machine Learning · Computer Science 2012-03-19 Yan Yan , Romer Rosales , Glenn Fung , Jennifer Dy

Even with the luxury of having abundant data, multi-label classification is widely known to be a challenging task to address. This work targets the problem of multi-label meta-learning, where a model learns to predict multiple labels within…

Computer Vision and Pattern Recognition · Computer Science 2021-10-27 Christian Simon , Piotr Koniusz , Mehrtash Harandi

Deep neural network models have demonstrated their effectiveness in classifying multi-label data from various domains. Typically, they employ a training mode that combines mini-batches with optimizers, where each sample is randomly selected…

Machine Learning · Computer Science 2024-03-28 Ao Zhou , Bin Liu , Jin Wang , Grigorios Tsoumakas

Deep learning-based object detectors have achieved impressive performance in microscopy imaging, yet their confidence estimates often lack calibration, limiting their reliability for biomedical applications. In this work, we introduce a new…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Francesco Campi , Lucrezia Tondo , Ekin Karabati , Johannes Betge , Marie Piraud

Multi-label learning (MLL) has gained attention for its ability to represent real-world data. Label Distribution Learning (LDL), an extension of MLL to learning from label distributions, faces challenges in collecting accurate label…

Machine Learning · Computer Science 2025-02-04 Zhiqiang Kou , Si Qin , Hailin Wang , Mingkun Xie , Shuo Chen , Yuheng Jia , Tongliang Liu , Masashi Sugiyama , Xin Geng

Annotation cost is a bottleneck for collecting massive data in mammography, especially for training deep neural networks. In this paper, we study the use of heterogeneous levels of annotation granularity to improve predictive performances.…

Image and Video Processing · Electrical Eng. & Systems 2019-09-13 Thi-Lam-Thuy Le , Nicolas Thome , Sylvain Bernard , Vincent Bismuth , Fanny Patoureaux

Single-cell RNA sequencing has transformed our ability to identify diverse cell types and their transcriptomic signatures. However, annotating these signatures-especially those involving poorly characterized genes-remains a major challenge.…

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Akihiko Yoshizawa , Tetsuo Ushiku , Masashi Fukayama , Masanobu Kitagawa , Masaru Kitsuregawa , Tatsuya Harada

Segmentation and classification of cell nuclei in histopathology images using deep neural networks (DNNs) can save pathologists' time for diagnosing various diseases, including cancers, by automating cell counting and morphometric…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Amruta Parulekar , Utkarsh Kanwat , Ravi Kant Gupta , Medha Chippa , Thomas Jacob , Tripti Bameta , Swapnil Rane , Amit Sethi