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Medical image registration is a fundamental task in medical image analysis, aiming to establish spatial correspondences between paired images. However, existing unsupervised deformable registration methods rely solely on intensity-based…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Hao Xu , Tengfei Xue , Jianan Fan , Dongnan Liu , Yuqian Chen , Fan Zhang , Carl-Fredrik Westin , Ron Kikinis , Lauren J. O'Donnell , Weidong Cai

The PI-CAI (Prostate Imaging: Cancer AI) challenge led to expert-level diagnostic algorithms for clinically significant prostate cancer detection. The algorithms receive biparametric MRI scans as input, which consist of T2-weighted and…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Alessa Hering , Sarah de Boer , Anindo Saha , Jasper J. Twilt , Mattias P. Heinrich , Derya Yakar , Maarten de Rooij , Henkjan Huisman , Joeran S. Bosma

Deep metrics have been shown effective as similarity measures in multi-modal image registration; however, the metrics are currently constructed from aligned image pairs in the training data. In this paper, we propose a strategy for learning…

Computer Vision and Pattern Recognition · Computer Science 2018-04-06 Alireza Sedghi , Jie Luo , Alireza Mehrtash , Steve Pieper , Clare M. Tempany , Tina Kapur , Parvin Mousavi , William M. Wells

Image registration and in particular deformable registration methods are pillars of medical imaging. Inspired by the recent advances in deep learning, we propose in this paper, a novel convolutional neural network architecture that couples…

Computer Vision and Pattern Recognition · Computer Science 2018-09-18 Stergios Christodoulidis , Mihir Sahasrabudhe , Maria Vakalopoulou , Guillaume Chassagnon , Marie-Pierre Revel , Stavroula Mougiakakou , Nikos Paragios

Magnetic Resonance Imaging (MRI) typically recruits multiple sequences (defined here as "modalities"). As each modality is designed to offer different anatomical and functional clinical information, there are evident disparities in the…

Image and Video Processing · Electrical Eng. & Systems 2022-03-09 Chengjia Wang , Guang Yang , Giorgos Papanastasiou

Cortical surface registration is a fundamental tool for neuroimaging analysis that has been shown to improve the alignment of functional regions relative to volumetric approaches. Classically, image registration is performed by optimizing a…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Mohamed A. Suliman , Logan Z. J. Williams , Abdulah Fawaz , Emma C. Robinson

Deformable image registration can obtain dynamic information about images, which is of great significance in medical image analysis. The unsupervised deep learning registration method can quickly achieve high registration accuracy without…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Xiao Fan , Shuxin Zhuang , Zhemin Zhuang , Ye Yuan , Shunmin Qiu , Alex Noel Joseph Raj , Yibiao Rong

Deformable image registration is a crucial step in medical image analysis for finding a non-linear spatial transformation between a pair of fixed and moving images. Deep registration methods based on Convolutional Neural Networks (CNNs)…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Mingyuan Meng , Lei Bi , Dagan Feng , Jinman Kim

Multimodal groupwise registration aligns internal structures in a group of medical images. Current approaches to this problem involve developing similarity measures over the joint intensity profile of all images, which may be…

Computer Vision and Pattern Recognition · Computer Science 2022-12-13 Xin Wang , Xinzhe Luo , Xiahai Zhuang

We present KeyMorph, a deep learning-based image registration framework that relies on automatically detecting corresponding keypoints. State-of-the-art deep learning methods for registration often are not robust to large misalignments, are…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Alan Q. Wang , Evan M. Yu , Adrian V. Dalca , Mert R. Sabuncu

Multimodal image registration (MIR) is a fundamental procedure in many image-guided therapies. Recently, unsupervised learning-based methods have demonstrated promising performance over accuracy and efficiency in deformable image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Zhe Xu , Jiangpeng Yan , Jie Luo , Xiu Li , Jayender Jagadeesan

Deformable image registration (DIR) involves optimization of multiple conflicting objectives, however, not many existing DIR algorithms are multi-objective (MO). Further, while there has been progress in the design of deep learning…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Monika Grewal , Henrike Westerveld , Peter A. N. Bosman , Tanja Alderliesten

Image registration is an ill-posed inverse problem which often requires regularisation on the solution space. In contrast to most of the current approaches which impose explicit regularisation terms such as smoothness, in this paper we…

Image and Video Processing · Electrical Eng. & Systems 2020-07-09 Chen Qin , Shuo Wang , Chen Chen , Huaqi Qiu , Wenjia Bai , Daniel Rueckert

Recently, deep-learning-based approaches have been widely studied for deformable image registration task. However, most efforts directly map the composite image representation to spatial transformation through the convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Jiashun Chen , Donghuan Lu , Yu Zhang , Dong Wei , Munan Ning , Xinyu Shi , Zhe Xu , Yefeng Zheng

Multi-modal image registration is a crucial pre-processing step in many medical applications. However, it is a challenging task due to the complex intensity relationships between different imaging modalities, which can result in large…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Vasiliki Sideri-Lampretsa , Veronika A. Zimmer , Huaqi Qiu , Georgios Kaissis , Daniel Rueckert

Deformable registration has been one of the pillars of biomedical image computing. Conventional approaches refer to the definition of a similarity criterion that, once endowed with a deformation model and a smoothness constraint, determines…

Computer Vision and Pattern Recognition · Computer Science 2018-09-25 Enzo Ferrante , Puneet K. Dokania , Rafael Marini Silva , Nikos Paragios

In this paper, we propose a deep learning approach for image registration by predicting deformation from image appearance. Since obtaining ground-truth deformation fields for training can be challenging, we design a fully convolutional…

Computer Vision and Pattern Recognition · Computer Science 2018-02-14 Jingfan Fan , Xiaohuan Cao , Pew-Thian Yap , Dinggang Shen

The establishment of image correspondence through robust image registration is critical to many clinical tasks such as image fusion, organ atlas creation, and tumor growth monitoring, and is a very challenging problem. Since the beginning…

Quantitative Methods · Quantitative Biology 2020-01-22 Grant Haskins , Uwe Kruger , Pingkun Yan

Rigid registration aims to determine the translations and rotations necessary to align features in a pair of images. While recent machine learning methods have become state-of-the-art for linear and deformable registration across subjects,…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Jingru Fu , Adrian V. Dalca , Bruce Fischl , Rodrigo Moreno , Malte Hoffmann

This paper introduces GeoMorph, a novel geometric deep-learning framework designed for image registration of cortical surfaces. The registration process consists of two main steps. First, independent feature extraction is performed on each…

Machine Learning · Computer Science 2023-11-23 Mohamed A. Suliman , Logan Z. J. Williams , Abdulah Fawaz , Emma C. Robinson
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