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Diffusion Tensor Cardiac Magnetic Resonance (DT-CMR) enables us to probe the microstructural arrangement of cardiomyocytes within the myocardium in vivo and non-invasively, which no other imaging modality allows. This innovative technology…

We use machine learning to perform super-resolution analysis of grossly under-resolved turbulent flow field data to reconstruct the high-resolution flow field. Two machine-learning models are developed; namely the convolutional neural…

Segmentation of medical images is a fundamental task with numerous applications. While MRI, CT, and PET modalities have significantly benefited from deep learning segmentation techniques, more recent modalities, like functional ultrasound…

Segmentation of the aorta is crucial for various medical analyses, such as the diagnosis and treatment of cardiovascular diseases. This work presents mathematical models and methods yielding a semi-automatic segmentation of the aorta from…

As the original velocity field obtained from four-dimensional (4D) flow magnetic resonance imaging (MRI) contains considerable amount of noises and errors, the available Divergence-free smoothing (DFS) method can be used to process the 4D…

The extent to which advanced waveform analysis of non-invasive physiological signals can diagnose levels of hypovolemia remains insufficiently explored. The present study explores the discriminative ability of a deep learning (DL) framework…

Deep learning-based 3-dimensional (3D) shape reconstruction from 2-dimensional (2D) magnetic resonance imaging (MRI) has become increasingly important in medical disease diagnosis, treatment planning, and computational modeling. This review…

A joint image reconstruction and segmentation approach based on disentangled representation learning was trained to enable cardiac cine MR imaging in real-time and under free-breathing. An exploratory feasibility study tested the proposed…

Cardiac Magnetic Resonance (CMR) is established as a non-invasive imaging technique for evaluation of heart function, anatomy, and myocardial tissue characterization. Quantitative biomarkers are central for diagnosis and management of heart…

Computational ultrasound imaging (cUSi) with few elements and spatial field encoding can provide high-resolution volumetric B-mode imaging. In this work, we extend its application to 4D carotid artery (CA) flow imaging using a custom…

We introduce SMURF, a scalable and unsupervised machine learning method for simultaneously segmenting vascular geometries and reconstructing velocity fields from 4D flow MRI data. SMURF models geometry and velocity fields using multilayer…

Accurate three-dimensional (3D) reconstruction of cardiac chamber motion from time-resolved medical imaging modalities is of growing interest in both the clinical and biomechanical fields. Despite recent advancement, the cardiac motion…

Numerical simulations on fluid dynamics problems primarily rely on spatially or/and temporally discretization of the governing equation into the finite-dimensional algebraic system solved by computers. Due to complicated nature of the…

Coronary artery disease (CAD) remains the world's leading cause of mortality and the disease burden is continually expanding as the population ages. Recently, the MR-INFORM randomised trial has demonstrated that the management of patients…

In this work we propose to validate the predictive capabilities of one-dimensional (1D) blood flow models with full three-dimensional (3D) models in the context of patient-specific coronary hemodynamics in hyperemic conditions. Such…

The standard non-invasive imaging technique used to assess the severity and extent of Coronary Artery Disease (CAD) is Coronary Computed Tomography Angiography (CCTA). However, manual grading of each patient's CCTA according to the…

Magnetic Resonance Spectroscopic Imaging (MRSI) is a non-invasive imaging technique for studying metabolism and has become a crucial tool for understanding neurological diseases, cancers and diabetes. High spatial resolution MRSI is needed…

Following successful large-vessel recanalization via endovascular thrombectomy (EVT) for acute ischemic stroke (AIS), some patients experience a complication known as no-reflow, defined by persistent microvascular hypoperfusion that…

Automated noninvasive cardiac diagnosis plays a critical role in the early detection of cardiac disorders and cost-effective clinical management. Automated diagnosis involves the automated segmentation and analysis of cardiac images.…

It is known that the maximum diameter for the rupture-risk assessment of the abdominal aortic aneurysm is a generally good method, but not sufficient. Alternative features obtained with computational modeling may provide additional useful…