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Stochastic systems in biology often exhibit substantial variability within and between cells. This variability, as well as having dramatic functional consequences, provides information about the underlying details of the system's behaviour.…

Quantitative Methods · Quantitative Biology 2015-11-09 Iain G. Johnston

Genetic data obtained on population samples convey information about their evolutionary history. Inference methods can extract this information (at least partially) but they require sophisticated statistical techniques that have been made…

In this paper we propose and study local linear and polynomial based estimators for implementing Approximate Bayesian Computation (ABC) style indirect inference and GMM estimators. This method makes use of nonparametric regression in the…

Statistics Theory · Mathematics 2020-03-13 Michael Creel , Jiti Gao , Han Hong , Dennis Kristensen

We use approximate Bayesian computation (ABC) to estimate unknown parameter values, as well as their uncertainties, in Reynolds-averaged Navier-Stokes (RANS) simulations of turbulent flows. The ABC method approximates posterior…

Fluid Dynamics · Physics 2020-11-04 Olga A. Doronina , Scott M. Murman , Peter E. Hamlington

Approximate Bayesian computing is a powerful likelihood-free method that has grown increasingly popular since early applications in population genetics. However, complications arise in the theoretical justification for Bayesian inference…

Computation · Statistics 2018-12-03 Suzanne Thornton , Wentao Li , Min-ge Xie

We address the problem of parameter estimation in models of systems biology from noisy observations. The models we consider are characterized by simultaneous deterministic nonlinear differential equations whose parameters are either taken…

Machine Learning · Statistics 2017-05-01 Xin Liu , Mahesan Niranjan

A popular method for likelihood-free inference is approximate Bayesian computation sequential Monte Carlo (ABC-SMC) algorithms. These approximate the posterior using a population of particles, which are updated using Markov kernels. Several…

Computation · Statistics 2025-11-11 Dennis Prangle , Cecilia Viscardi , Sammy Ragy

Sequential techniques can enhance the efficiency of the approximate Bayesian computation algorithm, as in Sisson et al.'s (2007) partial rejection control version. While this method is based upon the theoretical works of Del Moral et al.…

Computation · Statistics 2010-10-11 Mark A. Beaumont , Jean-Marie Cornuet , Jean-Michel Marin , Christian P. Robert

We present an informal review of recent work on the asymptotics of Approximate Bayesian Computation (ABC). In particular we focus on how does the ABC posterior, or point estimates obtained by ABC, behave in the limit as we have more data?…

Methodology · Statistics 2017-06-26 Paul Fearnhead

Missing data is a recurrent issue in epidemiology where the infection process may be partially observed. Approximate Bayesian Computation, an alternative to data imputation methods such as Markov Chain Monte Carlo integration, is proposed…

Applications · Statistics 2010-08-31 Michael G. B. Blum , Viet Chi Tran

Individual-based models of contagious processes are useful for predicting epidemic trajectories and informing intervention strategies. In such models, the incorporation of contact network information can capture the non-randomness and…

Populations and Evolution · Quantitative Biology 2023-11-09 Maxwell H. Wang , Jukka-Pekka Onnela

F-ABC is introduced, using universal sufficient statistics, unlike previous ABC papers, e.g. Bernton et al. (2019), and avoiding in the approximate posterior artifacts due to a Kernel. The nature of matching tolerance is examined and…

Methodology · Statistics 2020-07-14 Yannis G. Yatracos

We develop a Bayesian inference method for discretely-observed stochastic differential equations (SDEs). Inference is challenging for most SDEs, due to the analytical intractability of the likelihood function. Nevertheless, forward…

Methodology · Statistics 2024-11-08 Petar Jovanovski , Andrew Golightly , Umberto Picchini

In recent years, methods of approximate parameter estimation have attracted considerable interest in complex problems where exact likelihoods are hard to obtain. In their most basic form, Bayesian methods such as Approximate Bayesian…

Computation · Statistics 2015-07-17 Johanna Bertl , Gregory Ewing , Carolin Kosiol , Andreas Futschik

This chapter will appear in the forthcoming Handbook of Approximate Bayesian Computation (2018). Indirect inference (II) is a classical likelihood-free approach that pre-dates the main developments of ABC and relies on simulation from a…

Computation · Statistics 2018-03-07 Christopher C Drovandi

Simulation-based inference has been popular for amortized Bayesian computation. It is typical to have more than one posterior approximation, from different inference algorithms, different architectures, or simply the randomness of…

Methodology · Statistics 2024-03-04 Yuling Yao , Bruno Régaldo-Saint Blancard , Justin Domke

Bayesian methods provide an elegant framework for estimating parameter posteriors and quantification of uncertainty associated with probabilistic models. However, they often suffer from slow inference times. To address this challenge,…

Machine Learning · Computer Science 2024-05-10 Piyush Tiwary , Kumar Shubham , Vivek V. Kashyap , Prathosh A. P

ABC algorithms involve a large number of simulations from the model of interest, which can be very computationally costly. This paper summarises the lazy ABC algorithm of Prangle (2015), which reduces the computational demand by abandoning…

Computation · Statistics 2015-01-22 Dennis Prangle

Given the complexity of modern cosmological parameter inference where we are faced with non-Gaussian data and noise, correlated systematics and multi-probe correlated data sets, the Approximate Bayesian Computation (ABC) method is a…

Instrumentation and Methods for Astrophysics · Physics 2017-03-08 Elise Jennings , Maeve Madigan

Kernel density estimation is a widely used nonparametric approach to estimate an unknown distribution. Recent work in Bayesian predictive inference has considered stochastic processes formed by specifying the predictive distribution for the…

Methodology · Statistics 2026-05-15 Torey Hilbert
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