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Related papers: Probing restricted diffusion and exchange using fr…

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The dependence of the diffusion MRI signal on the diffusion time carries signatures of restricted diffusion and exchange. Here we seek to highlight these signatures in the human brain by performing experiments using free gradient waveforms…

The K\"arger model and its derivatives have been widely used to incorporate transcytolemmal water exchange rate, an essential characteristic of living cells, into analyses of diffusion MRI (dMRI) signals from tissues. The K\"arger model…

Medical Physics · Physics 2024-11-08 Diwei Shi , Fan Liu , Sisi Li , Li Chen , Xiaoyu Jiang , John C. Gore , Quanshui Zheng , Hua Guo , Junzhong Xu

Diffusion MRI (dMRI) provides contrast that reflect diffusing spins' interactions with microstructural features of biological systems, but its specificity remains limited due to the ambiguity of its relation to the underlying…

Medical Physics · Physics 2022-03-29 Jonas L. Olesen , Leif Østergaard , Noam Shemesh , Sune N. Jespersen

Time-dependent diffusion MRI enables the estimation of water exchange rates in vivo, yet reported values in grey matter remain inconsistent. While most studies attribute these estimates to membrane permeability, non-permeative geometric…

Diffusion Magnetic Resonance Imaging (dMRI) is an imaging technique with exquisite sensitivity to the microstructural properties of heterogeneous media. The conventionally adopted acquisition schemes involving single pulsed field gradients…

Biological Physics · Physics 2023-01-04 Deneb Boito , Cem Yolcu , Evren Özarslan

Real-world data generation often involves complex inter-dependencies among instances, violating the IID-data hypothesis of standard learning paradigms and posing a challenge for uncovering the geometric structures for learning desired…

Machine Learning · Computer Science 2023-05-30 Qitian Wu , Chenxiao Yang , Wentao Zhao , Yixuan He , David Wipf , Junchi Yan

Discrete element method simulations of confined bidisperse granular shear flows elucidate the balance between diffusion and segregation that can lead to either mixed or segregated states, depending on confining pressure. Results indicate…

Soft Condensed Matter · Physics 2018-09-24 Alexander M. Fry , Paul B. Umbanhowar , Julio M. Ottino , Richard M. Lueptow

Water diffusion MRI is a very powerful tool for probing tissue microstructure, but disentangling the contribution of compartment-specific structural disorder from cellular restriction and inter-compartment exchange remains an open…

Medical Physics · Physics 2024-02-09 Eloïse Mougel , Julien Valette , Marco Palombo

Diffusion encoding along multiple spatial directions per signal acquisition can be described in terms of a b-tensor. The benefit of tensor-valued diffusion encoding is that it unlocks the "shape of the b-tensor" as a new encoding dimension.…

Medical Physics · Physics 2020-11-18 Filip Szczepankiewicz , Carl-Fredrik Westin , Markus Nilsson

Demixing of binary fluids subjected to slow temperature ramps shows repeated waves of nucleation which arise as a consequence of the competition between generation of supersaturation by the temperature ramp and relaxation of supersaturation…

Statistical Mechanics · Physics 2012-10-16 Izabella J. Benczik , Jürgen Vollmer

Purpose: Asymmetric gradient waveforms are attractive for diffusion encoding due to their superior efficiency, however, the asymmetry may cause a residual gradient moment at the end of the encoding. Depending on the experiment setup, this…

Medical Physics · Physics 2019-09-05 Filip Szczepankiewicz , Carl-Fredrik Westin , Markus Nilsson

When polydisperse granular systems are sheared, the transverse dynamics is characterized by the interplay of size segregation and diffusion. Segregation in nonuniform and confined shearing flows is studied using annular shear cell…

Other Condensed Matter · Physics 2026-01-29 Santiago Caro , Riccardo Artoni , Patrick Richard , Michele Larcher , James T. Jenkins

Biophysical models in diffusion MRI (dMRI) hold promise for characterizing gray matter tissue microstructure. Yet, the reliability of their parameter estimates remains largely under-studied, especially in models that incorporate water…

Restrictions to molecular motion by barriers (membranes) are ubiquitous in biological tissues, porous media and composite materials. A major challenge is to characterize the microstructure of a material or an organism nondestructively using…

Soft Condensed Matter · Physics 2011-03-11 Dmitry S. Novikov , Els Fieremans , Jens H. Jensen , Joseph A. Helpern

Purpose: Stimulated echo acquisition mode (STEAM) diffusion MRI can be advantageous over pulsed-gradient spin-echo (PGSE) for diffusion times that are long compared to $\ttwo$. It is important therefore for biomedical diffusion imaging…

Medical Physics · Physics 2013-06-13 Daniel C. Alexander , Tim B. Dyrby

Interactions between inertia-gravity waves and balanced flows lead to a spectral diffusion of wave action. Prior work has established that this diffusion is weak across constant frequency surfaces in three-dimensional settings, but can be…

Fluid Dynamics · Physics 2026-05-04 Nicholas DeFilippis , Oliver Bühler , K. Shafer Smith

Purpose: Biophysical models of diffusion MRI have been developed to characterize microstructure in various tissues, but existing models are not suitable for tissue composed of permeable spherical cells. In this study we introduce Cellular…

The time dependency of the diffusion coefficient of particles in porous media is an efficient probe of their geometry. The analysis of this quantity, measured e.g. by nuclear magnetic resonance (PGSE-NMR), can provide rich information…

Soft Condensed Matter · Physics 2013-02-13 Maximilien Levesque , Olivier Bénichou , Benjamin Rotenberg

Diffusion in an evolving environment is studied by continuos-time Monte Carlo simulations. Diffusion is modelled by continuos-time random walkers on a lattice, in a dynamic environment provided by bubbles between two one-dimensional…

Soft Condensed Matter · Physics 2010-11-22 Janne Juntunen , Juha Merikoski

Diffusion-weighted MRI is the forerunner of the rapidly developed microstructural MRI aimed at in vivo evaluation of the cellular tissue architecture. This brief review focuses on the spatiotemporal scales of the microstructure that are…

Medical Physics · Physics 2020-08-14 Valerij G. Kiselev
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