English
Related papers

Related papers: Explainable Biomedical Recommendations via Reinfor…

200 papers

Multi-hop reasoning (MHR) is a process in artificial intelligence and natural language processing where a system needs to make multiple inferential steps to arrive at a conclusion or answer. In the context of knowledge graphs or databases,…

Artificial Intelligence · Computer Science 2024-06-13 Jesmin Jahan Tithi , Fabio Checconi , Fabrizio Petrini

Multi-hop reasoning approaches over knowledge graphs infer a missing relationship between entities with a multi-hop rule, which corresponds to a chain of relationships. We extend existing works to consider a generalized form of multi-hop…

Computation and Language · Computer Science 2020-10-06 Lu Zhang , Mo Yu , Tian Gao , Yue Yu

Deep learning has recently gained popularity in digital pathology due to its high prediction quality. However, the medical domain requires explanation and insight for a better understanding beyond standard quantitative performance…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Miriam Hägele , Philipp Seegerer , Sebastian Lapuschkin , Michael Bockmayr , Wojciech Samek , Frederick Klauschen , Klaus-Robert Müller , Alexander Binder

Clinical diagnosis guidelines aim at specifying the steps that may lead to a diagnosis. Inspired by guidelines, we aim to learn the optimal sequence of actions to perform in order to obtain a correct diagnosis from electronic health…

Machine Learning · Computer Science 2023-11-16 Lillian Muyama , Antoine Neuraz , Adrien Coulet

How neural networks in the human brain represent commonsense knowledge, and complete related reasoning tasks is an important research topic in neuroscience, cognitive science, psychology, and artificial intelligence. Although the…

Neural and Evolutionary Computing · Computer Science 2022-07-13 Hongjian Fang , Yi Zeng , Jianbo Tang , Yuwei Wang , Yao Liang , Xin Liu

A pharmacological effect of a drug on cells, organs and systems refers to the specific biochemical interaction produced by a drug substance, which is called its mechanism of action. Drug repositioning (or drug repurposing) is a fundamental…

Machine Learning · Computer Science 2020-05-19 Dehua Chen , Amir Jalilifard , Adriano Veloso , Nivio Ziviani

Explainability is key to enhancing artificial intelligence's trustworthiness in medicine. However, several issues remain concerning the actual benefit of explainable models for clinical decision-making. Firstly, there is a lack of consensus…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Kazuma Kobayashi , Yasuyuki Takamizawa , Mototaka Miyake , Sono Ito , Lin Gu , Tatsuya Nakatsuka , Yu Akagi , Tatsuya Harada , Yukihide Kanemitsu , Ryuji Hamamoto

Path reasoning is a notable recommendation approach that models high-order user-product relations, based on a Knowledge Graph (KG). This approach can extract reasoning paths between recommended products and already experienced products and,…

Information Retrieval · Computer Science 2023-01-18 Giacomo Balloccu , Ludovico Boratto , Christian Cancedda , Gianni Fenu , Mirko Marras

While large language models show promise in medical applications, achieving expert-level clinical reasoning remains challenging due to the need for both accurate answers and transparent reasoning processes. To address this challenge, we…

Machine Learning · Computer Science 2025-09-22 Chi Liu , Derek Li , Yan Shu , Robin Chen , Derek Duan , Teng Fang , Bryan Dai

The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

Computation and Language · Computer Science 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

The use of symbolic knowledge representation and reasoning as a way to resolve the lack of transparency of machine learning classifiers is a research area that lately attracts many researchers. In this work, we use knowledge graphs as the…

Artificial Intelligence · Computer Science 2022-02-09 Edmund Dervakos , Orfeas Menis-Mastromichalakis , Alexandros Chortaras , Giorgos Stamou

Existing studies on disease diagnostic models focus either on diagnostic model learning for performance improvement or on the visual explanation of a trained diagnostic model. We propose a novel learn-explain-reinforce (LEAR) framework that…

Computer Vision and Pattern Recognition · Computer Science 2021-08-24 Kwanseok Oh , Jee Seok Yoon , Heung-Il Suk

In this work, we present our various contributions to the objective of building a decision support tool for the diagnosis of rare diseases. Our goal is to achieve a state of knowledge where the uncertainty about the patient's disease is…

Graph neural networks (GNNs) are powerful graph-based deep-learning models that have gained significant attention and demonstrated remarkable performance in various domains, including natural language processing, drug discovery, and…

Machine Learning · Computer Science 2023-06-06 Jaykumar Kakkad , Jaspal Jannu , Kartik Sharma , Charu Aggarwal , Sourav Medya

Answering questions that require multi-hop reasoning at web-scale necessitates retrieving multiple evidence documents, one of which often has little lexical or semantic relationship to the question. This paper introduces a new graph-based…

Computation and Language · Computer Science 2020-02-17 Akari Asai , Kazuma Hashimoto , Hannaneh Hajishirzi , Richard Socher , Caiming Xiong

Objective: Disease knowledge graphs are a way to connect, organize, and access disparate information about diseases with numerous benefits for artificial intelligence (AI). To create knowledge graphs, it is necessary to extract knowledge…

Machine Learning · Computer Science 2022-09-01 Yucong Lin , Keming Lu , Sheng Yu , Tianxi Cai , Marinka Zitnik

To make machines better understand sentiments, research needs to move from polarity identification to understanding the reasons that underlie the expression of sentiment. Categorizing the goals or needs of humans is one way to explain the…

Computation and Language · Computer Science 2019-04-02 Debjit Paul , Anette Frank

Explainable recommendation attempts to develop models that generate not only high-quality recommendations but also intuitive explanations. The explanations may either be post-hoc or directly come from an explainable model (also called…

Information Retrieval · Computer Science 2020-09-15 Yongfeng Zhang , Xu Chen

Recent progress in retrieval-augmented generation (RAG) has led to more accurate and interpretable multi-hop question answering (QA). Yet, challenges persist in integrating iterative reasoning steps with external knowledge retrieval. To…

Computation and Language · Computer Science 2025-10-06 Tengjun Ni , Xin Yuan , Shenghong Li , Kai Wu , Ren Ping Liu , Wei Ni , Wenjie Zhang

Diagnosing cognitive (mental health) disorders is a delicate and complex task. Identifying the next most informative symptoms to assess, in order to distinguish between possible disorders, presents an additional challenge. This process…

Information Retrieval · Computer Science 2025-11-25 Raoul H. Kutil , Georg Zimmermann , Christian Borgelt