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Within developing embryos, tissues flow and reorganize dramatically on timescales as short as minutes. This includes epithelial tissues, which often narrow and elongate in convergent extension movements due to anisotropies in external…

Tissues and Organs · Quantitative Biology 2020-06-24 Xun Wang , Matthias Merkel , Leo B. Sutter , Gonca Erdemci-Tandogan , M. Lisa Manning , Karen E. Kasza

Cellularized tissue and polymer networks can both transition from floppy to rigid as a function of their control parameters, and, yet, the two systems often mechanically interact, which may affect their respective rigidities. To study this…

Cell Behavior · Quantitative Biology 2020-06-30 Amanda Parker , M. Cristina Marchetti , M. Lisa Manning , J. M. Schwarz

A new phase field model of microstructural evolution is presented that includes the effects of elastic strain energy. The model's thin interface behavior is investigated by mapping it onto a recent model developed by Echebarria et al (Phys…

Materials Science · Physics 2008-10-29 Michael Greenwood , Jeffrey J. Hoyt , Nikolas Provatas

The ability of cells to reorganize in response to external stimuli is important in areas ranging from morphogenesis to tissue engineering. Elongated cells can co-align due to steric effects, forming states with local order. We show that…

We investigate the effect of an anisotropic substrate on the turbulent dynamics of a simulated two dimensional active nematic. This is introduced as an anisotropic friction and an effective anisotropic viscosity, with the orientation of the…

Soft Condensed Matter · Physics 2019-06-12 D. J. G. Pearce

Besides the chemical constituents, it is the lattice geometry that controls the most important material properties. In many interesting compounds, the arrangement of elements leads to pronounced anisotropies, which reflect into a varying…

Strongly Correlated Electrons · Physics 2021-01-27 Benjamin Klebel , Thomas Schäfer , Alessandro Toschi , Jan M. Tomczak

In order to investigate the role of the weight in weighted networks, the collective behavior of the Ising system on weighted regular networks is studied by numerical simulation. In our model, the coupling strength between spins is inversely…

Statistical Mechanics · Physics 2013-10-01 Menghui Li , Ying Fan , Jinshan Wu , Zengru Di

Athermal models of disordered fibrous networks are highly useful for studying the mechanics of elastic networks composed of stiff biopolymers. The underlying network architecture is a key aspect that can affect the elastic properties of…

Soft Condensed Matter · Physics 2016-01-20 Albert James Licup , Abhinav Sharma , Fred C. MacKintosh

We propose and analyse the properties of a new class of models for the electromechanics of cardiac tissue. The set of governing equations consists of nonlinear elasticity using a viscoelastic and orthotropic exponential constitutive law…

Numerical Analysis · Mathematics 2022-04-08 Adrienne Propp , Alessio Gizzi , Francesc Levrero-Florencio , Ricardo Ruiz-Baier

Engineering synthetic materials that mimic the remarkable complexity of living organisms is a fundamental challenge in science and technology. We study the spatiotemporal patterns that emerge when an active nematicfilm of microtubules and…

The collective behaviour of confluent cell sheets is strongly influenced both by polar forces, arising through cytoskeletal propulsion and by active inter-cellular forces, which are mediated by interactions across cell-cell junctions. We…

Soft Condensed Matter · Physics 2020-05-28 Guanming Zhang , Romain Mueller , Amin Doostmohammadi , Julia M. Yeomans

Cell layers eliminate unwanted cells through the extrusion process, which underlines healthy versus flawed tissue behaviors. Although several biochemical pathways have been identified, the underlying mechanical basis including the forces…

Soft Condensed Matter · Physics 2023-04-20 Siavash Monfared , Guruswami Ravichandran , Jose E. Andrade , Amin Doostmohammadi

We study the dynamics of the solid to liquid transition for a model material made of elastic particles immersed in a viscous fluid. The interaction between particle surfaces includes their viscous lubrication, a sharp repulsion when they…

Fluid Dynamics · Physics 2015-05-14 P. Rognon , I. Einav , C. Gay

We investigate how randomly oriented cell traction forces lead to fluidisation in a vertex model of epithelial tissues. We find that the fluidisation occurs at a critical value of the traction force magnitude $F_c$. We show that this…

Soft Condensed Matter · Physics 2022-11-07 Aboutaleb Amiri , Charlie Duclut , Frank Jülicher , Marko Popović

Physical experiments can characterize the elastic response of granular materials in terms of macroscopic state-variables, namely volume (packing) fraction and stress, while the microstructure is not accessible and thus neglected. Here, by…

Soft Condensed Matter · Physics 2015-06-16 Nishant Kumar , Stefan Luding , Vanessa Magnanimo

The alignment of fibers and cells in living tissues affect their mechanical properties and functionality. In this context, one can draw an analogy between tissues and nematic liquid crystal elastomers. We explore this analogy by growing…

Soft Condensed Matter · Physics 2025-10-08 Kirsten Endresen , Aniruddh Murali , Birte Geerds , Daniel J. G. Pearce , Francesca Serra

Graphene layers are stable, hard, and relatively inert. We study how tensile stress affects $\sigma$ and $\pi$ bonds and the resulting change in the chemical activity. Stress affects more strongly $\pi$ bonds that can become chemically…

Materials Science · Physics 2015-05-13 P. L. de andres , J. A. Verges

We present a generic formulation of the continuum elasticity of an isotropic crosslinked active gel. The gel is described by a two-component model consisting of an elastic network coupled frictionally to a permeating fluid. Activity is…

Soft Condensed Matter · Physics 2011-04-22 Shiladitya Banerjee , M. Cristina Marchetti

We study the viscoelasticity of an active solution of polar biofilaments and motor proteins. Using a molecular model, we derive the constitutive equations for the stress tensor in the isotropic phase and in phases with liquid crystalline…

Soft Condensed Matter · Physics 2009-11-11 T. B. Liverpool , M. Cristina Marchetti

Active matter encompasses different nonequilibrium systems in which individual constituents convert energy into non-conservative forces or motion at the microscale. This review provides an elementary introduction to the role of topology in…

Soft Condensed Matter · Physics 2022-06-28 Suraj Shankar , Anton Souslov , Mark J. Bowick , M. Cristina Marchetti , Vincenzo Vitelli