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Molecular traits, such as gene expression levels or protein binding affinities, are increasingly accessible to quantitative measurement by modern high-throughput techniques. Such traits measure molecular functions and, from an evolutionary…

Populations and Evolution · Quantitative Biology 2013-11-15 Armita Nourmohammad , Torsten Held , Michael Lässig

A Martin-L\"of test $\mathcal U$ is universal if it captures all non-Martin-L\"of random sequences, and it is optimal if for every ML-test $\mathcal V$ there is a $c \in \omega$ such that $\forall n(\mathcal{V}_{n+c} \subseteq…

Logic · Mathematics 2014-10-10 Rupert Hölzl , Paul Shafer

While statistical learning methods have proved powerful tools for predictive modeling, the black-box nature of the models they produce can severely limit their interpretability and the ability to conduct formal inference. However, the…

Machine Learning · Statistics 2016-08-30 Lucas Mentch , Giles Hooker

The question of how best to estimate a continuous probability density from finite data is an intriguing open problem at the interface of statistics and physics. Previous work has argued that this problem can be addressed in a natural way…

Data Analysis, Statistics and Probability · Physics 2014-07-16 Justin B. Kinney

The widespread use of generative models has created a feedback loop, in which each generation of models is trained on data partially produced by its predecessors. This process has raised concerns about model collapse: A critical degradation…

Machine Learning · Statistics 2026-03-27 Daniel Barzilai , Ohad Shamir

Sampling from high-dimensional probability distributions is fundamental in machine learning and statistics. As datasets grow larger, computational efficiency becomes increasingly important, particularly in reducing adaptive complexity,…

Data Structures and Algorithms · Computer Science 2025-09-23 Huanjian Zhou , Masashi Sugiyama

Calibration of mean estimates for predictions is a crucial property in many applications, particularly in the fields of financial and actuarial decision-making. In this paper, we first review classical approaches for validating…

Applications · Statistics 2025-10-29 Łukasz Delong , Mario Wüthrich

Ensuring robust model performance in diverse real-world scenarios requires addressing generalizability across domains with covariate shifts. However, no formal procedure exists for statistically evaluating generalizability in machine…

Machine Learning · Computer Science 2025-06-13 Daniel de Vassimon Manela , Linying Yang , Robin J. Evans

Understanding statistical inference under possibly non-sparse high-dimensional models has gained much interest recently. For a given component of the regression coefficient, we show that the difficulty of the problem depends on the sparsity…

Statistics Theory · Mathematics 2022-08-22 Jelena Bradic , Jianqing Fan , Yinchu Zhu

The log-normal distribution is used to describe the positive data, that it has skewed distribution with small mean and large variance. This distribution has application in many sciences for example medicine, economics, biology and…

Methodology · Statistics 2015-08-10 Saba Aghadoust , Kamel Abdollahnezhad , Farhad Yaghmaei , Ali Akbar Jafari

Given the intractably large size of the space of proofs, any model that is capable of general deductive reasoning must generalize to proofs of greater complexity. Recent studies have shown that large language models (LLMs) possess some…

Computation and Language · Computer Science 2023-11-07 Abulhair Saparov , Richard Yuanzhe Pang , Vishakh Padmakumar , Nitish Joshi , Seyed Mehran Kazemi , Najoung Kim , He He

A logconcave likelihood is as important to proper statistical inference as a convex cost function is important to variational optimization. Quantization is often disregarded when writing likelihood models, ignoring the limitations of the…

Signal Processing · Electrical Eng. & Systems 2023-01-25 Pol del Aguila Pla , Aleix Boquet-Pujadas , Joakim Jaldén

Modern machine learning embeddings provide powerful compression of high-dimensional data, yet they typically destroy the geometric structure required for classical likelihood-based statistical inference. This paper develops a rigorous…

Machine Learning · Statistics 2025-12-30 Deniz Akdemir

The network data has attracted considerable attention in modern statistics. In research on complex network data, one key issue is finding its underlying connection structure given a network sample. The methods that have been proposed in…

Methodology · Statistics 2024-08-09 Kang Fu , Jianwei Hu , Seydou Keita

Local smoothing testing that is based on multivariate nonparametric regression estimation is one of the main model checking methodologies in the literature. However, relevant tests suffer from the typical curse of dimensionality resulting…

Methodology · Statistics 2014-05-12 Xu Guo , Lixing Zhu

The estimation of a log-concave density on $\mathbb{R}$ is a canonical problem in the area of shape-constrained nonparametric inference. We present a Bayesian nonparametric approach to this problem based on an exponentiated Dirichlet…

Statistics Theory · Mathematics 2020-07-14 Ester Mariucci , Kolyan Ray , Botond Szabo

In this paper, we study the problem of sampling from log-concave distributions supported on convex, compact sets, with a particular focus on the randomized midpoint discretization of both vanilla and kinetic Langevin diffusions in this…

Machine Learning · Statistics 2025-05-27 Yifeng Yu , Lu Yu

Although deep learning models have driven state-of-the-art performance on a wide array of tasks, they are prone to spurious correlations that should not be learned as predictive clues. To mitigate this problem, we propose a causality-based…

Machine Learning · Computer Science 2021-10-27 Xinyi Wang , Wenhu Chen , Michael Saxon , William Yang Wang

Inference problems with conjectured statistical-computational gaps are ubiquitous throughout modern statistics, computer science and statistical physics. While there has been success evidencing these gaps from the failure of restricted…

Computational Complexity · Computer Science 2020-06-30 Matthew Brennan , Guy Bresler

From the perspective of data reduction, the notions of minimal sufficient and complete statistics together play an important role in determining optimal statistics (estimators). The classical notion of sufficiency and completeness are not…

Statistics Theory · Mathematics 2025-10-16 Himanshi Singh , Tanmay Sahoo , Nil Kamal Hazra