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The classification of electrocardiogram (ECG) plays a crucial role in the development of an automatic cardiovascular diagnostic system. However, considerable variances in ECG signals between individuals is a significant challenge. Changes…

Signal Processing · Electrical Eng. & Systems 2023-06-08 Md Niaz Imtiaz , Naimul Khan

We introduce ICE-TIDE, a method for cryogenic electron tomography (cryo-ET) that simultaneously aligns observations and reconstructs a high-resolution volume. The alignment of tilt series in cryo-ET is a major problem limiting the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-16 Valentin Debarnot , Vinith Kishore , Ricardo D. Righetto , Ivan Dokmanić

Single-particle cryo-electron microscopy (cryo-EM) has become a cornerstone of structural biology, enabling near-atomic resolution analysis of macromolecules through advanced computational methods. However, the development of cryo-EM…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Runmin Jiang , Genpei Zhang , Yuntian Yang , Siqi Wu , Minhao Wu , Wanyue Feng , Yizhou Zhao , Xi Xiao , Xiao Wang , Tianyang Wang , Xingjian Li , Muyuan Chen , Min Xu

Cryo-electron microscopy (cryo-EM) is an imaging modality that provides unique insights into the dynamics of proteins and other building blocks of life. The algorithmic challenge of jointly estimating the poses, 3D structure, and…

Computer Vision and Pattern Recognition · Computer Science 2022-10-17 Axel Levy , Gordon Wetzstein , Julien Martel , Frederic Poitevin , Ellen D. Zhong

Recent unsupervised domain adaptation methods based on deep architectures have shown remarkable performance not only in traditional classification tasks but also in more complex problems involving structured predictions (e.g. semantic…

Computer Vision and Pattern Recognition · Computer Science 2020-08-05 Levi O. Vasconcelos , Massimiliano Mancini , Davide Boscaini , Samuel Rota Bulo , Barbara Caputo , Elisa Ricci

Single-particle cryo-electron microscopy (cryo-EM) has become one of the mainstream structural biology techniques because of its ability to determine high-resolution structures of dynamic bio-molecules. However, cryo-EM data acquisition…

Machine Learning · Computer Science 2022-04-18 Quanfu Fan , Yilai Li , Yuguang Yao , John Cohn , Sijia Liu , Seychelle M. Vos , Michael A. Cianfrocco

Cryo-electron microscopy (cryo-EM) has recently become a premier method for obtaining high-resolution structures of biological macromolecules. However, it is limited to biomolecular samples with low conformational heterogeneity, where all…

Neural networks often require large amounts of expert annotated data to train. When changes are made in the process of medical imaging, trained networks may not perform as well, and obtaining large amounts of expert annotations for each…

Image and Video Processing · Electrical Eng. & Systems 2021-08-05 Nicolas Ewen , Naimul Khan

The success of deep learning has set new benchmarks for many medical image analysis tasks. However, deep models often fail to generalize in the presence of distribution shifts between training (source) data and test (target) data. One…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Dwarikanath Mahapatra

Deep learning model trained by imbalanced data may not work satisfactorily since it could be determined by major classes and thus may ignore the classes with small amount of data. In this paper, we apply deep learning based imbalanced data…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Ziqian Luo , Xiangrui Zeng , Zhipeng Bao , Min Xu

In cryo-electron microscopy, accurate particle localization and classification are imperative. Recent deep learning solutions, though successful, require extensive training data sets. The protracted generation time of physics-based models,…

Machine Learning · Computer Science 2025-02-20 Pavol Harar , Lukas Herrmann , Philipp Grohs , David Haselbach

Electrical Impedance Tomography (EIT) is a powerful imaging technique with diverse applications, e.g., medical diagnosis, industrial monitoring, and environmental studies. The EIT inverse problem is about inferring the internal conductivity…

Machine Learning · Computer Science 2023-10-31 Derick Nganyu Tanyu , Jianfeng Ning , Andreas Hauptmann , Bangti Jin , Peter Maass

Supervised learning with large scale labeled datasets and deep layered models has made a paradigm shift in diverse areas in learning and recognition. However, this approach still suffers generalization issues under the presence of a domain…

Machine Learning · Statistics 2016-03-28 Ozan Sener , Hyun Oh Song , Ashutosh Saxena , Silvio Savarese

Deep learning models deployed in real-world applications (e.g., medicine) face challenges because source models do not generalize well to domain-shifted target data. Many successful domain adaptation (DA) approaches require full access to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Mainak Biswas , Ambedkar Dukkipati , Devarajan Sridharan

State-of-the-art approaches to infer dense depth measurements from images rely on CNNs trained end-to-end on a vast amount of data. However, these approaches suffer a drastic drop in accuracy when dealing with environments much different in…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Alessio Tonioni , Matteo Poggi , Stefano Mattoccia , Luigi Di Stefano

Cellular Electron Cryo-Tomography (CECT) is a powerful 3D imaging tool for studying the native structure and organization of macromolecules inside single cells. For systematic recognition and recovery of macromolecular structures captured…

Computer Vision and Pattern Recognition · Computer Science 2018-07-04 Chang Liu , Xiangrui Zeng , Kaiwen Wang , Qiang Guo , Min Xu

Generalising deep models to new data from new centres (termed here domains) remains a challenge. This is largely attributed to shifts in data statistics (domain shifts) between source and unseen domains. Recently, gradient-based…

Computer Vision and Pattern Recognition · Computer Science 2021-10-05 Xiao Liu , Spyridon Thermos , Alison O'Neil , Sotirios A. Tsaftaris

Enhancing cryogenic electron microscopy (cryo-EM) 3D density maps at intermediate resolution (4-8 {\AA}) is crucial in protein structure determination. Recent advances in deep learning have led to the development of automated approaches for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-16 Chenwei Zhang , Khanh Dao Duc

Direct image-to-graph transformation is a challenging task that involves solving object detection and relationship prediction in a single model. Due to this task's complexity, large training datasets are rare in many domains, making the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Alexander H. Berger , Laurin Lux , Suprosanna Shit , Ivan Ezhov , Georgios Kaissis , Martin J. Menten , Daniel Rueckert , Johannes C. Paetzold

One weakness of machine-learning algorithms is the need to train the models for a new task. This presents a specific challenge for biometric recognition due to the dynamic nature of databases and, in some instances, the reliance on subject…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Kevin Hernandez-Diaz , Fernando Alonso-Fernandez , Josef Bigun
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