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Retinal disease diagnosis is critical in preventing vision loss and reducing socioeconomic burdens. Globally, over 2.2 billion people are affected by some form of vision impairment, resulting in annual productivity losses estimated at $411…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Youssef Sabiri , Walid Houmaidi , Amine Abouaomar

In ophthalmology, early fundus screening is an economic and effective way to prevent blindness caused by ophthalmic diseases. Clinically, due to the lack of medical resources, manual diagnosis is time-consuming and may delay the condition.…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Ning Li , Tao Li , Chunyu Hu , Kai Wang , Hong Kang

Deep neural networks (DNNs) have promoted the development of computer aided diagnosis (CAD) systems for fundus diseases, helping ophthalmologists reduce missed diagnosis and misdiagnosis rate. However, the majority of CAD systems are…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Hongyang Jiang , Jingqi Huang , Chen Tang , Xiaoqing Zhang , Mengdi Gao , Jiang Liu

This paper experiments with the number of fully-connected layers in a deep convolutional neural network as applied to the classification of fundus retinal images. The images analysed corresponded to the ODIR 2019 (Peking University…

Image and Video Processing · Electrical Eng. & Systems 2020-04-15 Ajna Ram , Constantino Carlos Reyes-Aldasoro

Diabetic retinopathy (DR) is one of the leading causes of blindness. However, no specific symptoms of early DR lead to a delayed diagnosis, which results in disease progression in patients. To determine the disease severity levels,…

Computer Vision and Pattern Recognition · Computer Science 2020-11-05 Li Tian , Liyan Ma , Zhijie Wen , Shaorong Xie , Yupeng Xu

Widespread outreach programs using remote retinal imaging have proven to decrease the risk from diabetic retinopathy, the leading cause of blindness in the US. However, this process still requires manual verification of image quality and…

Computer Vision and Pattern Recognition · Computer Science 2016-12-14 Arjun Raj Rajanna , Kamelia Aryafar , Rajeev Ramchandran , Christye Sisson , Ali Shokoufandeh , Raymond Ptucha

An overview of the applications of deep learning in ophthalmic diagnosis using retinal fundus images is presented. We also review various retinal image datasets that can be used for deep learning purposes. Applications of deep learning for…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Sourya Sengupta , Amitojdeep Singh , Henry A. Leopold , Tanmay Gulati , Vasudevan Lakshminarayanan

Deep long-tailed learning, one of the most challenging problems in visual recognition, aims to train well-performing deep models from a large number of images that follow a long-tailed class distribution. In the last decade, deep learning…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Yifan Zhang , Bingyi Kang , Bryan Hooi , Shuicheng Yan , Jiashi Feng

Segmentation and classification of cell nuclei in histopathology images using deep neural networks (DNNs) can save pathologists' time for diagnosing various diseases, including cancers, by automating cell counting and morphometric…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Amruta Parulekar , Utkarsh Kanwat , Ravi Kant Gupta , Medha Chippa , Thomas Jacob , Tripti Bameta , Swapnil Rane , Amit Sethi

Diabetic retinopathy is one of the most threatening complications of diabetes that leads to permanent blindness if left untreated. One of the essential challenges is early detection, which is very important for treatment success.…

Machine Learning · Computer Science 2020-03-06 Borys Tymchenko , Philip Marchenko , Dmitry Spodarets

Retinal diseases remain among the leading preventable causes of visual impairment worldwide. Automated screening based on fundus image analysis has the potential to expand access to early detection, particularly in underserved populations.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Ali Akram

Rare diseases have extremely low-data regimes, unlike common diseases with large amount of available labeled data. Hence, to train a neural network to classify rare diseases with a few per-class data samples is very challenging, and so far,…

Computer Vision and Pattern Recognition · Computer Science 2020-07-16 Xiaomeng Li , Lequan Yu , Yueming Jin , Chi-Wing Fu , Lei Xing , Pheng-Ann Heng

Long-tailed datasets, where head classes comprise much more training samples than tail classes, cause recognition models to get biased towards the head classes. Weighted loss is one of the most popular ways of mitigating this issue, and a…

Computer Vision and Pattern Recognition · Computer Science 2022-09-08 Saptarshi Sinha , Hiroki Ohashi

Skin conditions are reported the 4th leading cause of nonfatal disease burden worldwide. However, given the colossal spectrum of skin disorders defined clinically and shortage in dermatology expertise, diagnosing skin conditions in a timely…

Computer Vision and Pattern Recognition · Computer Science 2020-07-15 Junyan Wu , Hao Jiang , Xiaowei Ding , Anudeep Konda , Jin Han , Yang Zhang , Qian Li

Deep learning has been successfully applied to a variety of image classification tasks. There has been keen interest to apply deep learning in the medical domain, particularly specialties that heavily utilize imaging, such as ophthalmology.…

Machine Learning · Computer Science 2019-02-13 Rony Gelman

Deep learning models have the capacity to fundamentally revolutionize medical imaging analysis, and they have particularly interesting applications in computer-aided diagnosis. We attempt to use deep learning neural networks to diagnose…

Machine Learning · Computer Science 2020-02-24 Rohit Jammula , Vishnu Rajan Tejus , Shreya Shankar

This paper presents a comparative analysis of deep learning strategies for detecting hypertensive retinopathy from fundus images, a central task in the HRDC challenge~\cite{qian2025hrdc}. We investigate three distinct approaches: a custom…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Yanqiao Zhu

In many real-world applications, the frequency distribution of class labels for training data can exhibit a long-tailed distribution, which challenges traditional approaches of training deep neural networks that require heavy amounts of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Richard Franklin , Jiawei Yao , Deyang Zhong , Qi Qian , Juhua Hu

Deep learning enables impressive performance in image recognition using large-scale artificially-balanced datasets. However, real-world datasets exhibit highly class-imbalanced distributions, yielding two main challenges: relative imbalance…

Computer Vision and Pattern Recognition · Computer Science 2020-10-20 Saurabh Sharma , Ning Yu , Mario Fritz , Bernt Schiele

In the medical domain, acquiring large datasets poses significant challenges due to privacy concerns. Nonetheless, the development of a robust deep-learning model for retinal disease diagnosis necessitates a substantial dataset for…

Computer Vision and Pattern Recognition · Computer Science 2024-09-18 Fatema-E- Jannat , Sina Gholami , Jennifer I. Lim , Theodore Leng , Minhaj Nur Alam , Hamed Tabkhi