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A lack of understanding of human biology creates a hurdle for the development of precision medicines. To overcome this hurdle we need to better understand the potential synergy between a given investigational treatment (vs. placebo or…

Applications · Statistics 2017-08-17 Jia Jia , Qi Tang , Wangang Xie , Richard Rode

An important task in early phase drug development is to identify patients, which respond better or worse to an experimental treatment. While a variety of different subgroup identification methods have been developed for the situation of…

Methodology · Statistics 2020-01-22 Marius Thomas , Björn Bornkamp , Heidi Seibold

Vision Transformers (ViTs) have gained significant popularity in recent years and have proliferated into many applications. However, their behavior under different learning paradigms is not well explored. We compare ViTs trained through…

Computer Vision and Pattern Recognition · Computer Science 2023-04-07 Matthew Walmer , Saksham Suri , Kamal Gupta , Abhinav Shrivastava

Identifying patient subgroups with different treatment responses is an important task to inform medical recommendations, guidelines, and the design of future clinical trials. Existing approaches for treatment effect estimation primarily…

Methodology · Statistics 2025-12-10 Vincent Jeanselme , Chang Ho Yoon , Fabian Falck , Brian Tom , Jessica Barrett

Transformer design is the de facto standard for natural language processing tasks. The success of the transformer design in natural language processing has lately piqued the interest of researchers in the domain of computer vision. When…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Md Sohag Mia , Abu Bakor Hayat Arnob , Abdu Naim , Abdullah Al Bary Voban , Md Shariful Islam

Identifying subgroups, which respond differently to a treatment, both in terms of efficacy and safety, is an important part of drug development. A well-known challenge in exploratory subgroup analyses is the small sample size in the…

Computation · Statistics 2016-06-28 Marius Thomas , Björn Bornkamp

Humans possess remarkable ability to accurately classify new, unseen images after being exposed to only a few examples. Such ability stems from their capacity to identify common features shared between new and previously seen images while…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Weihao Jiang , Chang Liu , Kun He

Patients in clinical studies often exhibit heterogeneous treatment effect (HTE). Classical subgroup analyses provide inferential tools to test for effect modification, while modern machine learning methods estimate the Conditional Average…

Applications · Statistics 2026-01-05 Nan Miles Xi , Xin Huang , Lin Wang

Fine-grained visual classification (FGVC) which aims at recognizing objects from subcategories is a very challenging task due to the inherently subtle inter-class differences. Most existing works mainly tackle this problem by reusing the…

Computer Vision and Pattern Recognition · Computer Science 2021-12-03 Ju He , Jie-Neng Chen , Shuai Liu , Adam Kortylewski , Cheng Yang , Yutong Bai , Changhu Wang

Self-Supervised Learning (SSL) for Vision Transformers (ViTs) has recently demonstrated considerable potential as a pre-training strategy for a variety of computer vision tasks, including image classification and segmentation, both in…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Yannis Kaltampanidis , Alexandros Doumanoglou , Dimitrios Zarpalas

Out of the participants in a randomized experiment with anticipated heterogeneous treatment effects, is it possible to identify which subjects have a positive treatment effect? While subgroup analysis has received attention, claims about…

Methodology · Statistics 2024-05-14 Boyan Duan , Larry Wasserman , Aaditya Ramdas

Subgroup selection in clinical trials is essential for identifying patient groups that react differently to a treatment, thereby enabling personalised medicine. In particular, subgroup selection can identify patient groups that respond…

We present a novel method that extends the self-attention mechanism of a vision transformer (ViT) for more accurate object detection across diverse datasets. ViTs show strong capability for image understanding tasks such as object…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Tan Nguyen , Coy D. Heldermon , Corey Toler-Franklin

Understanding treatment heterogeneity is essential to the development of precision medicine, which seeks to tailor medical treatments to subgroups of patients with similar characteristics. One of the challenges to achieve this goal is that…

Methodology · Statistics 2019-08-21 Shujie Ma , Jian Huang , Zhiwei Zhang , Mingming Liu

This paper investigates the effectiveness of self-supervised pre-trained vision transformers (ViTs) compared to supervised pre-trained ViTs and conventional neural networks (ConvNets) for detecting facial deepfake images and videos. It…

Computer Vision and Pattern Recognition · Computer Science 2024-08-12 Huy H. Nguyen , Junichi Yamagishi , Isao Echizen

There is strong interest in estimating how the magnitude of treatment effects of an intervention vary across sub-groups of the population of interest. In our paper, we propose a two-study approach to first propose and then test…

Methodology · Statistics 2020-06-23 Rahul Ladhania , Amelia Haviland , Neeraj Sood , Edward Kennedy , Ateev Mehrotra

Vision transformers (ViTs) have been successfully applied in image classification tasks recently. In this paper, we show that, unlike convolution neural networks (CNNs)that can be improved by stacking more convolutional layers, the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Daquan Zhou , Bingyi Kang , Xiaojie Jin , Linjie Yang , Xiaochen Lian , Zihang Jiang , Qibin Hou , Jiashi Feng

Precise estimation of treatment effects is crucial for evaluating intervention effectiveness. While deep learning models have exhibited promising performance in learning counterfactual representations for treatment effect estimation (TEE),…

Machine Learning · Computer Science 2024-01-24 Seungyeon Lee , Ruoqi Liu , Wenyu Song , Lang Li , Ping Zhang

Vision Transformers (ViTs) have attracted a lot of popularity in recent years, due to their exceptional capabilities in modeling long-range spatial dependencies and scalability for large scale training. Although the training parallelism of…

Computer Vision and Pattern Recognition · Computer Science 2024-01-29 Ali Hatamizadeh , Michael Ranzinger , Shiyi Lan , Jose M. Alvarez , Sanja Fidler , Jan Kautz

Vision Transformers (ViTs) are becoming more popular and dominating technique for various vision tasks, compare to Convolutional Neural Networks (CNNs). As a demanding technique in computer vision, ViTs have been successfully solved various…

Computer Vision and Pattern Recognition · Computer Science 2023-10-18 Khawar Islam
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