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Score-based generative models (SGMs) have recently shown promising results for image reconstruction on simulated positron emission tomography (PET) datasets. In this work we have developed and implemented practical methodology for 3D image…

Rapid advancements in medical image segmentation performance have been significantly driven by the development of Convolutional Neural Networks (CNNs) and Vision Transformers (ViTs). These models follow the discriminative pixel-wise…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Jiayu Huo , Xi Ouyang , Sébastien Ourselin , Rachel Sparks

Recent advances in generative artificial intelligence have had a significant impact on diverse domains spanning computer vision, natural language processing, and drug discovery. This work extends the reach of generative models into physical…

Machine Learning · Computer Science 2024-10-22 Christian Jacobsen , Yilin Zhuang , Karthik Duraisamy

Over the last years, deep learning methods have become an increasingly popular choice to solve tasks from the field of inverse problems. Many of these new data-driven methods have produced impressive results, although most only give point…

Image and Video Processing · Electrical Eng. & Systems 2021-10-28 Alexander Denker , Maximilian Schmidt , Johannes Leuschner , Peter Maass

Image inpainting refers to the restoration of an image with missing regions in a way that is not detectable by the observer. The inpainting regions can be of any size and shape. This is an ill-posed inverse problem that does not have a…

Computer Vision and Pattern Recognition · Computer Science 2022-05-05 Coloma Ballester , Aurelie Bugeau , Samuel Hurault , Simone Parisotto , Patricia Vitoria

Diffusion models have shown impressive performance for image generation, often times outperforming other generative models. Since their introduction, researchers have extended the powerful noise-to-image denoising pipeline to discriminative…

Image and Video Processing · Electrical Eng. & Systems 2023-12-21 Fahim Ahmed Zaman , Mathews Jacob , Amanda Chang , Kan Liu , Milan Sonka , Xiaodong Wu

Signal reconstruction is a challenging aspect of computational imaging as it often involves solving ill-posed inverse problems. Recently, deep feed-forward neural networks have led to state-of-the-art results in solving various inverse…

Computer Vision and Pattern Recognition · Computer Science 2018-04-25 Akshat Dave , Anil Kumar Vadathya , Ramana Subramanyam , Rahul Baburajan , Kaushik Mitra

Machine learning methods for computational imaging require uncertainty estimation to be reliable in real settings. While Bayesian models offer a computationally tractable way of recovering uncertainty, they need large data volumes to be…

Machine Learning · Computer Science 2020-08-24 Francesco Tonolini , Jack Radford , Alex Turpin , Daniele Faccio , Roderick Murray-Smith

Semantic segmentation of medical images is pivotal in applications like disease diagnosis and treatment planning. While deep learning has excelled in automating this task, a major hurdle is the need for numerous annotated segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-09-02 Li Zhang , Basu Jindal , Ahmed Alaa , Robert Weinreb , David Wilson , Eran Segal , James Zou , Pengtao Xie

Inverse imaging problems that are ill-posed can be encountered across multiple domains of science and technology, ranging from medical diagnosis to astronomical studies. To reconstruct images from incomplete and distorted data, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Cesar F. Caiafa , Ramiro M. Irastorza

Score-based generative models have demonstrated significant practical success in data-generating tasks. The models establish a diffusion process that perturbs the ground truth data to Gaussian noise and then learn the reverse process to…

Machine Learning · Computer Science 2024-05-24 Ziqing Wen , Xiaoge Deng , Ping Luo , Tao Sun , Dongsheng Li

This work presents an unsupervised deep learning scheme that exploiting high-dimensional assisted score-based generative model for color image restoration tasks. Considering that the sample number and internal dimension in score-based…

Image and Video Processing · Electrical Eng. & Systems 2021-08-17 Kai Hong , Chunhua Wu , Cailian Yang , Minghui Zhang , Yancheng Lu , Yuhao Wang , Qiegen Liu

Data-driven medical AI is traditionally formulated as a discriminative mapping from input $X$ to output $Y$ via a learned function $f$, which does not generalize well across heterogeneous data and modalities encountered in real-world…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Hantao Zhang , Weidong Guo , Yuhe Liu , Jiancheng Yang , Sathvik Bhagavan , Danli Shi , Mingda Xu , Pascal Fua

Since most inverse problems arising in scientific and engineering applications are ill-posed, prior information about the solution space is incorporated, typically through regularization, to establish a well-posed problem with a unique…

Signal Processing · Electrical Eng. & Systems 2024-06-18 Carter Lyons , Raghu G. Raj , Margaret Cheney

Pretrained segmentation models for cardiac magnetic resonance imaging (MRI) struggle to generalize across different imaging sequences due to significant variations in image contrast. These variations arise from changes in imaging protocols,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Yidong Zhao , Peter Kellman , Hui Xue , Tongyun Yang , Yi Zhang , Yuchi Han , Orlando Simonetti , Qian Tao

In the field of quantitative imaging, the image information at a pixel or voxel in an underlying domain entails crucial information about the imaged matter. This is particularly important in medical imaging applications, such as…

Optimization and Control · Mathematics 2024-04-12 Guozhi Dong , Moritz Flaschel , Michael Hintermüller , Kostas Papafitsoros , Clemens Sirotenko , Karsten Tabelow

While score based generative models, or diffusion models, have found success in image synthesis, they are often coupled with text data or image label to be able to manipulate and conditionally generate images. Even though manipulation of…

Computer Vision and Pattern Recognition · Computer Science 2023-02-07 Sandesh Ghimire , Armand Comas , Davin Hill , Aria Masoomi , Octavia Camps , Jennifer Dy

Solving ill-posed inverse problems requires careful formulation of prior beliefs over the signals of interest and an accurate description of their manifestation into noisy measurements. Handcrafted signal priors based on e.g. sparsity are…

Machine Learning · Computer Science 2025-08-14 Tristan S. W. Stevens , Hans van Gorp , Faik C. Meral , Junseob Shin , Jason Yu , Jean-Luc Robert , Ruud J. G. van Sloun

Score-based generative models (SGMs) are a recent breakthrough in generating fake images. SGMs are known to surpass other generative models, e.g., generative adversarial networks (GANs) and variational autoencoders (VAEs). Being inspired by…

Machine Learning · Computer Science 2022-06-20 Jayoung Kim , Chaejeong Lee , Yehjin Shin , Sewon Park , Minjung Kim , Noseong Park , Jihoon Cho

We consider the general problem of recovering a high-dimensional signal from noisy quantized measurements. Quantization, especially coarse quantization such as 1-bit sign measurements, leads to severe information loss and thus a good prior…

Signal Processing · Electrical Eng. & Systems 2023-02-21 Xiangming Meng , Yoshiyuki Kabashima