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Reliable detection of the prodromal stages of Alzheimer's disease (AD) remains difficult even today because, unlike other neurocognitive impairments, there is no definitive diagnosis of AD in vivo. In this context, existing research has…

Machine Learning · Computer Science 2021-08-03 Amish Mittal , Sourav Sahoo , Arnhav Datar , Juned Kadiwala , Hrithwik Shalu , Jimson Mathew

Alzheimer's Disease (AD) dementia is a progressive neurodegenerative disease that negatively impacts patients' cognitive ability. Previous studies have demonstrated that changes in naturalistic language samples can be useful for early…

Computation and Language · Computer Science 2025-03-27 Changye Li , Zhecheng Sheng , Trevor Cohen , Serguei Pakhomov

Machine learning methods have shown large potential for the automatic early diagnosis of Alzheimer's Disease (AD). However, some machine learning methods based on imaging data have poor interpretability because it is usually unclear how…

Dementia is a neurodegenerative disease that causes gradual cognitive impairment, which is very common in the world and undergoes a lot of research every year to prevent and cure it. It severely impacts the patient's ability to remember…

Objective: this study has a twofold goal. First, it aims to improve the understanding of the impact of Dementia of type Alzheimer's Disease (AD) on different aspects of the lexicon. Second, it aims to demonstrate that such aspects of the…

Computation and Language · Computer Science 2023-07-18 M. Zakaria Kurdi

Formal thought disorder (FTD), a hallmark of schizophrenia spectrum disorders, manifests as incoherent speech and poses challenges for clinical assessment. Traditional clinical rating scales, though validated, are resource-intensive and…

Patients with semantic dementia (SD) present with remarkably consistent atrophy of neurons in the anterior temporal lobe and behavioural impairments, such as graded loss of category knowledge. While relearning of lost knowledge has been…

Machine Learning · Computer Science 2025-03-06 Devon Jarvis , Verena Klar , Richard Klein , Benjamin Rosman , Andrew Saxe

Alzheimer's disease and Frontotemporal dementia are two major types of dementia. Their accurate diagnosis and differentiation is crucial for determining specific intervention and treatment. However, differential diagnosis of these two types…

Image and Video Processing · Electrical Eng. & Systems 2022-06-16 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Speech is a rich biomarker that encodes substantial information about the health of a speaker, and thus it has been proposed for the detection of numerous diseases, achieving promising results. However, questions remain about what the…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-17 Catarina Botelho , Alberto Abad , Tanja Schultz , Isabel Trancoso

Joint models are used in ageing studies to investigate the association between longitudinal markers and a time-to-event, and have been extended to multiple markers and/or competing risks. The competing risk of death must be considered in…

Auditory attention decoding (AAD) is the process of identifying the attended speech in a multi-talker environment using brain signals, typically recorded through electroencephalography (EEG). Over the past decade, AAD has undergone…

Sound · Computer Science 2025-07-08 Nhan Duc Thanh Nguyen , Huy Phan , Simon Geirnaert , Kaare Mikkelsen , Preben Kidmose

Dementia, a progressive neurodegenerative disorder, affects memory, reasoning, and daily functioning, creating challenges for individuals and healthcare systems. Early detection is crucial for timely interventions that may slow disease…

Neurons and Cognition · Quantitative Biology 2025-03-04 Sahar Sinene Mehdoui , Abdelhamid Bouzid , Daniel Sierra-Sosa , Adel Elmaghraby

Dementia is a neuropsychiatric brain disorder that usually occurs when one or more brain cells stop working partially or at all. Diagnosis of this disorder in the early phases of the disease is a vital task to rescue patients lives from bad…

Machine Learning · Computer Science 2022-09-13 Sinan Faouri , Mahmood AlBashayreh , Mohammad Azzeh

Speech recognizers trained on close-talking speech do not generalize to distant speech and the word error rate degradation can be as large as 40% absolute. Most studies focus on tackling distant speech recognition as a separate problem,…

Computation and Language · Computer Science 2018-06-14 Hao Tang , Wei-Ning Hsu , Francois Grondin , James Glass

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to irreversible cognitive decline in memory and communication. Early detection of AD through speech analysis is crucial for delaying disease progression.…

Sound · Computer Science 2026-02-09 Yifan Gao , Long Guo , Hong Liu

Post-exercise speech contains rich physiological and linguistic cues, often marked by semantic pauses, breathing pauses, and combined breathing-semantic pauses. Detecting these events enables assessment of recovery rate, lung function, and…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-22 Yuyu Wang , Wuyue Xia , Huaxiu Yao , Jingping Nie

It has been shown recently that deep learning based models are effective on speech quality prediction and could outperform traditional metrics in various perspectives. Although network models have potential to be a surrogate for complex…

Sound · Computer Science 2022-11-15 Hsin-Yi Lin , Huan-Hsin Tseng , Yu Tsao

Speech is a common and effective way of communication between humans, and modern consumer devices such as smartphones and home hubs are equipped with deep learning based accurate automatic speech recognition to enable natural interaction…

Computation and Language · Computer Science 2018-01-03 Moustafa Alzantot , Bharathan Balaji , Mani Srivastava

Collecting and accessing a large amount of medical data is very time-consuming and laborious, not only because it is difficult to find specific patients but also because it is required to resolve the confidentiality of a patient's medical…

Sound · Computer Science 2021-03-04 Junghyun Koo , Jie Hwan Lee , Jaewoo Pyo , Yujin Jo , Kyogu Lee

With the global population aging rapidly, Alzheimer's disease (AD) is particularly prominent in older adults, which has an insidious onset and leads to a gradual, irreversible deterioration in cognitive domains (memory, communication,…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-15 Jinchao Li , Kaitao Song , Junan Li , Bo Zheng , Dongsheng Li , Xixin Wu , Xunying Liu , Helen Meng