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In this study, a computational simulation is employed to place two essential parameters, the permeability of vessels and hydraulic conductivity, under assessment. These parameters impact the movement of drug particles through vessels, and…

Tissues and Organs · Quantitative Biology 2023-04-14 Masod Sadipour , Mohammad Masoud Momeni , Majid Soltani

SUMMARY This work aims at quantifying the effect of inherent uncertainties from cardiac output on the sensitivity of a human compliant arterial network response based on stochastic simulations of a reduced-order pulse wave propagation…

Numerical Analysis · Mathematics 2016-06-22 A Brault , L Dumas , D Lucor

Quantum steering is an asymmetric form of quantum nonlocality where one can trust the measurements of one of the parties. In this work, inspired by practical considerations we investigate the scenario if one can not fully trust their…

Quantum Physics · Physics 2023-10-27 Shubhayan Sarkar

Estimation of conditional average treatment effects (CATEs) plays an essential role in modern medicine by informing treatment decision-making at a patient level. Several metalearners have been proposed recently to estimate CATEs in an…

Applications · Statistics 2022-09-07 Yizhe Xu , Nikolaos Ignatiadis , Erik Sverdrup , Scott Fleming , Stefan Wager , Nigam Shah

Uncertainty quantification in neural network promises to increase safety of AI systems, but it is not clear how performance might vary with the training set size. In this paper we evaluate seven uncertainty methods on Fashion MNIST and…

Machine Learning · Computer Science 2021-11-19 Matias Valdenegro-Toro

Randomized clinical trials are considered the gold standard for informing treatment guidelines, but results may not generalize to real-world populations. Generalizability is hindered by distributional differences in baseline covariates and…

Methodology · Statistics 2025-06-03 Rachael K. Ross , Ivan Diaz , Amy J. Pitts , Elizabeth A. Stuart , Kara E. Rudolph

In the most popular approach to the numerical study of the Anderson metal-insulator transition the transfer matrix method is combined with finite-size scaling ideas. This approach requires large computer resources to overcome the…

Disordered Systems and Neural Networks · Physics 2009-11-07 Alex P Taylor , Angus MacKinnon

The effect of quantum steering describes a possible action at a distance via local measurements. In the last few years, several criteria have been proposed to detect this type of correlation in quantum systems. However, there are few…

Quantum Physics · Physics 2024-04-16 L. Maquedano , A. C. S. Costa

In this paper, we review the recent activity of our group on the study of disorder effects on systems displaying phase coherence. These studies have focused on both the electronic transport through mesoscopic metallic spin glasses, and cold…

Disordered Systems and Neural Networks · Physics 2015-05-14 David Carpentier , Edmond Orignac , Guillame Paulin , Tommaso Roscilde

Purpose: Standard of care for various retinal diseases involves recurrent intravitreal injections. This motivates mathematical modelling efforts to identify influential factors for drug residence time, aiming to minimise administration…

Quantitative Methods · Quantitative Biology 2024-10-18 Patricia Lamirande , Eamonn A. Gaffney , Michael Gertz , Philip K. Maini , Jessica R. Crawshaw , Antonello Caruso

The primary objective of Phase I oncology trials is to assess the safety and tolerability of novel therapeutics. Conventional dose escalation methods identify the maximum tolerated dose (MTD) based on dose-limiting toxicity (DLT). However,…

Methodology · Statistics 2024-09-02 Yunlong Yang , Ying Yuan

We study the distribution of quantum steerability for continuous variables between two causally disconnected open charts in de Sitter space. It is shown that quantum steerability suffers from "sudden death" in de Sitter space, which is…

General Relativity and Quantum Cosmology · Physics 2020-02-05 Cuihong Wen , Jieci Wang , Jiliang Jing

We examine the effects of disorder in one-dimensional systems. We link the case of a few impurities, typical of a short quantum wire, to that of a finite density of scatterers more appropriate for a long wire or a macroscopic system.…

Condensed Matter · Physics 2007-05-23 Thierry Giamarchi , Hélène Maurey

Recent research in causal inference has made important progress in addressing challenges to the external validity of trial findings. Such methods weight trial participant data to more closely resemble the distribution of effect-modifying…

Methodology · Statistics 2024-07-18 Justin M. Clark , Kollin W. Rott , James S. Hodges , Jared D. Huling

A method is proposed for studying wave and particle transport in disordered waveguide systems of dimension higher than unity by means of exact one-dimensionalization of the dynamic equations in the mode representation. As a particular case,…

Disordered Systems and Neural Networks · Physics 2013-01-31 Yu. V. Tarasov

Controlled drug delivery (CDD), the controlled release and delivery of therapeutic drugs inside the human body, is a promising approach to increase the efficacy of drug administration and reduce harmful side effects to the body. CDD has…

Signal Processing · Electrical Eng. & Systems 2023-05-11 Sebastian Lotter , Tom Bellmann , Sophie Marx , Mara Wesinger , Lukas Brand , Maximilian Schäfer , Dagmar Fischer , Robert Schober

This paper shows how to use a randomized saturation experimental design to identify and estimate causal effects in the presence of spillovers--one person's treatment may affect another's outcome--and one-sided non-compliance--subjects can…

We present a theoretical and experimental study of light transport in disordered media with strongly heterogeneous distribution of scatterers formed via non-scattering regions. Step correlations induced by quenched disorder are found to…

Disordered Systems and Neural Networks · Physics 2014-03-05 Tomas Svensson , Kevin Vynck , Erik Adolfsson , Andrea Farina , Antonio Pifferi , Diederik S. Wiersma

We investigate the effect of both strong and weak potential scattering caused by local impurities and extended (line) defects in the array of Luttinger liquid wires. We find that in both cases a finite range inter-wire interaction…

Strongly Correlated Electrons · Physics 2017-10-10 A. L. Chudnovskiy , V. Kagalovsky , I. V. Yurkevich

Delineating and planning with respect to regions suspected to contain microscopic tumor cells is an inherently uncertain task in radiotherapy. The recently proposed \textit{clinical target distribution} (CTD) is an alternative to the…

Medical Physics · Physics 2023-04-26 Ivar Bengtsson , Anders Forsgren , Albin Fredriksson
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