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In many longitudinal microarray studies, the gene expression levels in a random sample are observed repeatedly over time under two or more conditions. The resulting time courses are generally very short, high-dimensional, and may have…

Applications · Statistics 2013-02-26 Maurice Berk , Cheryl Hemingway , Michael Levin , Giovanni Montana

Modern recording techniques enable neuroscientists to simultaneously study neural activity across large populations of neurons, with capturing predictor-dependent correlations being a fundamental challenge in neuroscience. Moreover, the…

Applications · Statistics 2025-02-04 Ganchao Wei

We provide a unified approach to a method of estimation of the regression parameter in balanced linear models with a structured covariance matrix that combines a high breakdown point and bounded influence with high asymptotic efficiency at…

Statistics Theory · Mathematics 2023-03-22 Hendrik Paul Lopuhaä

Dynamic prediction of time-to-event outcomes using longitudinal data is highly useful in clinical research and practice. A common strategy is the joint modeling of longitudinal and time-to-event data. The shared random effect model has been…

Methodology · Statistics 2025-05-27 Wenhao Li , Zhe Yin , Liang Li

Recent technological developments have enabled us to collect complex and high-dimensional data in many scientific fields, such as population health, meteorology, econometrics, geology, and psychology. It is common to encounter such datasets…

Methodology · Statistics 2020-03-16 Ufuk Beyaztas , Han Lin Shang

Many applications, such as in physical simulation and engineering design, demand we estimate functions with high-dimensional outputs. The training examples can be collected with different fidelities to allow a cost/accuracy trade-off. In…

Machine Learning · Computer Science 2021-10-27 Shibo Li , Robert M. Kirby , Shandian Zhe

Motivated by two case studies using primary care records from the Clinical Practice Research Datalink, we describe statistical methods that facilitate the analysis of tall data, with very large numbers of observations. Our focus is on…

Methodology · Statistics 2018-05-14 Kirsty Rhodes , Rebecca Turner , Rupert Payne , Ian White

As high-dimensional and high-frequency data are being collected on a large scale, the development of new statistical models is being pushed forward. Functional data analysis provides the required statistical methods to deal with large-scale…

Statistics Theory · Mathematics 2020-07-08 Israel Martínez-Hernández , Marc G. Genton

Heterogeneity in time series data is more pronounced than in vision or language, as temporal dynamics vary substantially across domains and tasks. Existing efforts on training time series foundation models (TSFMs) from scratch are often…

Machine Learning · Computer Science 2026-04-09 Shengchao Chen , Guodong Long , Dikai Liu , Jing Jiang

We propose a dual-factor model for high-dimensional functional time series (HDFTS) that considers multiple populations. The HDFTS is first decomposed into a collection of functional time series (FTS) in a lower dimension and a group of…

Methodology · Statistics 2024-05-13 Chen Tang , Han Lin Shang , Yanrong Yang , Yang Yang

Regression models with a response variable taking values in a Hilbert space and hybrid covariates are considered. This means two sets of regressors are allowed, one of finite dimension and a second one functional with values in a Hilbert…

Statistics Theory · Mathematics 2014-06-25 Samuel Maistre , Valentin Patilea

Recently, multi-modality scene perception tasks, e.g., image fusion and scene understanding, have attracted widespread attention for intelligent vision systems. However, early efforts always consider boosting a single task unilaterally and…

Computer Vision and Pattern Recognition · Computer Science 2023-05-12 Zhu Liu , Jinyuan Liu , Guanyao Wu , Long Ma , Xin Fan , Risheng Liu

Based on recent advancements in using machine learning for classical density functional theory for systems with one-dimensional, planar inhomogeneities, we propose a machine learning model for application in two dimensions (2D) akin to…

Statistical Mechanics · Physics 2025-05-22 Felix Glitsch , Jens Weimar , Martin Oettel

Multiphase flow phenomena have been widely observed in the industrial applications, yet it remains a challenging unsolved problem. Three-dimensional computational fluid dynamics (CFD) approaches resolve of the flow fields on finer spatial…

Fluid Dynamics · Physics 2020-05-11 Han Bao , Jinyong Feng , Nam Dinh , Hongbin Zhang

In this article, we propose a penalized clustering method for large scale data with multiple covariates through a functional data approach. In the proposed method, responses and covariates are linked together through nonparametric…

Methodology · Statistics 2008-01-17 Ping Ma , Wenxuan Zhong

High-dimensional linear classifiers, such as the support vector machine (SVM) and distance weighted discrimination (DWD), are commonly used in biomedical research to distinguish groups of subjects based on a large number of features.…

Methodology · Statistics 2017-10-20 Tianmeng Lyu , Eric F. Lock , Lynn E. Eberly

Convolutional neural networks (CNNs) have been the consensus for medical image segmentation tasks. However, they suffer from the limitation in modeling long-range dependencies and spatial correlations due to the nature of convolution…

Computer Vision and Pattern Recognition · Computer Science 2023-01-10 Moein Heidari , Amirhossein Kazerouni , Milad Soltany , Reza Azad , Ehsan Khodapanah Aghdam , Julien Cohen-Adad , Dorit Merhof

In high-dimensional data analysis, bi-level sparsity is often assumed when covariates function group-wisely and sparsity can appear either at the group level or within certain groups. In such cases, an ideal model should be able to…

Methodology · Statistics 2021-09-14 Bin Luo , Xiaoli Gao

Large-scale longitudinal molecular profiling is now firmly established in biomedical research, prompted by the need to uncover coordinated biomarker trajectories reflecting the dynamics of underlying biological mechanisms and characterise…

Methodology · Statistics 2026-03-24 Salima Jaoua , Daniel Temko , Hélène Ruffieux

In this paper, we propose methods for functional predictor selection and the estimation of smooth functional coefficients simultaneously in a scalar-on-function regression problem under high-dimensional multivariate functional data setting.…

Methodology · Statistics 2022-05-04 Ali Mahzarnia , Jun Song