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This Letter studies the quasispecies dynamics of a population capable of genetic repair evolving on a time-dependent fitness landscape. We develop a model that considers an asexual population of single-stranded, conservatively replicating…

Populations and Evolution · Quantitative Biology 2009-11-13 Pavel Gorodetsky , Emmanuel Tannenbaum

One of the most challenging issues of evolutionary biology concerns speciation, the emergence of new species from an initial one. The huge amount of species found in nature demands a simple and robust mechanism. Yet, no consensus has been…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Catarina R. Almeida , Fernão Vistulo de Abreu

Commonly recognized evolutionarily relevant effects of sexual reproduction include increased diversity, accelerated adaptation, and constrained accumulation of deleterious mutations, along with a secondary effect of species genotype…

Populations and Evolution · Quantitative Biology 2025-06-17 Assaf Marron , Smadar Szekely , Irun R. Cohen , David Harel

Many biological populations exhibit diversity in their strategy for survival and reproduction in a given environment, and microbes are an example. We explore the fate of different strategies under sustained environmental change by…

Populations and Evolution · Quantitative Biology 2025-09-24 Ruixi Huang , David Waxman

With a view to connecting random mutation on the molecular level to punctuated equilibrium behavior on the phenotype level, we propose a new model for biological evolution, which incorporates random mutation and natural selection. In this…

Condensed Matter · Physics 2009-10-28 M. Y. Choi , H. Y. Lee , D. Kim , S. H. Park

Genetically identical cells in the same population can take on phenotypically variable states, leading to differentiated responses to external signals, such as nutrients and drug-induced stress. Many models and experiments have focused on a…

Molecular Networks · Quantitative Biology 2015-04-28 Thierry Mora , Aleksandra M. Walczak

Parapatric speciation is studied using an individual--based model with sexual reproduction. We combine the theory of mutation accumulation for biological ageing with an environmental selection pressure that varies according to the…

Populations and Evolution · Quantitative Biology 2009-11-11 V. Schwammle , A. O. Sousa , S. M. de Oliveira

In unicellular organisms such as bacteria and in most viruses, mutations mainly occur during reproduction. Thus, genotypes with a high birth rate should have a higher mutation rate. However, standard models of asexual adaptation such as the…

Analysis of PDEs · Mathematics 2021-11-10 Florian Patout , R Forien , M Alfaro , J Papaïx , L Roques

Resource are often not uniformly distributed within a population. Spatial variations of concentration of a resource, change the fitness of competing strategies locally. The notion of fitness varying with respect to both genotype and…

Populations and Evolution · Quantitative Biology 2022-04-08 Hossein Nemati , Mohammad Reza Ejtehadi , Kamran Kaveh

We consider a reaction-diffusion model for a population structured in phenotype. We assume that the population lives in a heterogeneous periodic environment, so that a given phenotypic trait may be more or less fit according to the spatial…

Analysis of PDEs · Mathematics 2025-03-07 Nathanaël Boutillon , Luca Rossi

Maintenance of sexual reproduction and genetic recombination imposes physiological costs when compared to parthenogenic reproduction, most prominently: for maintaining the corresponding (molecular) machinery, for finding a mating partner,…

Populations and Evolution · Quantitative Biology 2016-05-24 Dmitri Parkhomchuk , Alice C. McHardy , Alexey Shadrin

We develop a continuous mathematical model of population dynamics that describes the sequential emergence of new genotypes under limited resources. The framework models genotype density as a nonlinear flow in mutation space, combining…

Populations and Evolution · Quantitative Biology 2025-12-10 Alexander Bratus , Tatiana Yakushkina , Vladimir Posvyanski

We review models of biological evolution in which the population frequency changes deterministically with time. If the population is self-replicating, although the equations for simple prototypes can be linearised, nonlinear equations arise…

Populations and Evolution · Quantitative Biology 2015-05-27 Kavita Jain , Sarada Seetharaman

The evolution of dispersal is a classical question in evolutionary ecology, which has been widely studied with several mathematical models. The main question is to define the fittest dispersal rate for a population in a bounded domain, and,…

Analysis of PDEs · Mathematics 2016-02-26 Benoit Perthame , Panagiotis E. Souganidis

We propose a model to characterize how a diffusing population adapts under a time periodic selection, while its environment undergoes shifts and size changes, leading to significant differences with classical results on fixed domains. After…

Analysis of PDEs · Mathematics 2025-06-05 Matthieu Alfaro , Adel Blouza , Nessim Dhaouadi

We consider a stochastic model for the evolution of a discrete population structured by a trait with values on a finite grid of the torus, and with mutation and selection. Traits are vertically inherited unless a mutation occurs, and…

Probability · Mathematics 2022-06-17 Nicolas Champagnat , Sylvie Méléard , Sepideh Mirrahimi , Viet Chi Tran

This article is concerned with the long time behavior of neutral genetic population models, with fixed population size. We design an explicit, finite, exact, genealogical tree based representation of stationary populations that holds both…

Probability · Mathematics 2007-05-23 Pierre Del Moral , Laurent Miclo , Frédéric Patras , Sylvain Rubenthaler

We investigate a continuous time, probability measure-valued dynamical system that describes the process of mutation-selection balance in a context where the population is infinite, there may be infinitely many loci, and there are weak…

Populations and Evolution · Quantitative Biology 2011-09-20 Steven N. Evans , David Steinsaltz , Kenneth W. Wachter

More and more evidence shows that mating preference is a mechanism that may lead to a reproductive isolation event. In this paper, a haploid population living on two patches linked by migration is considered. Individuals are ecologically…

Populations and Evolution · Quantitative Biology 2018-05-08 Helene Leman

Evolvability is defined as the ability of a population to generate heritable variation to facilitate its adaptation to new environments or selection pressures. In this article, we consider evolvability as a phenotypic trait subject to…

Populations and Evolution · Quantitative Biology 2025-06-03 Juan Jiménez-Sánchez , Carmen Ortega-Sabater , Philip K. Maini , Víctor M. Pérez-García , Tommaso Lorenzi
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