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Identifying shared genetic risk factors for multiple measured traits has been of great interest in studying complex disorders. Marlow's (2003) method for detecting shared gene effects on complex traits has been highly influential in the…

Methodology · Statistics 2009-04-16 Summer S. Han , Elena L. Grigorenko , Joseph T. Chang

Geometric graph models of systems as diverse as proteins, robots, and mechanical structures from DNA assemblies to architected materials point towards a unified way to represent and control them in space and time. While much work has been…

Robotics · Computer Science 2022-08-24 Siheng Chen , Fabio Giardina , Gary P. T. Choi , L. Mahadevan

Energy consumption is an important issue in continuous wireless telemonitoring of physiological signals. Compressed sensing (CS) is a promising framework to address it, due to its energy-efficient data compression procedure. However, most…

Information Theory · Computer Science 2014-11-18 Zhilin Zhang , Tzyy-Ping Jung , Scott Makeig , Zhouyue Pi , Bhaskar D. Rao

We propose a new outline for adaptive dictionary learning methods for sparse encoding based on a hierarchical clustering of the training data. Through recursive application of a clustering method, the data is organized into a binary…

Machine Learning · Computer Science 2020-06-11 Renato Budinich , Gerlind Plonka

DNA sequences encode critical genetic information, yet their variable length and discrete nature impede direct utilization in deep learning models. Existing DNA representation schemes convert sequences into numerical vectors but fail to…

Genomics · Quantitative Biology 2025-12-16 Zhiyuan Peng , Naifan Zhang , Yuanbo Tang , Yang Li

Phase retrieval consists in the recovery of an unknown signal from phaseless measurements of its usually complex-valued Fourier transform. Without further assumptions, this problem is notorious to be severe ill posed such that the recovery…

Information Theory · Computer Science 2023-01-19 Robert Beinert , Saghar Rezaei

It is widely believed that the success of deep networks lies in their ability to learn a meaningful representation of the features of the data. Yet, understanding when and how this feature learning improves performance remains a challenge:…

Machine Learning · Statistics 2022-10-13 Leonardo Petrini , Francesco Cagnetta , Eric Vanden-Eijnden , Matthieu Wyart

Compressed sensing provided a data-acquisition paradigm for sparse signals. Remarkably, it has been shown that practical algorithms provide robust recovery from noisy linear measurements acquired at a near optimal sampling rate. In many…

Information Theory · Computer Science 2017-08-03 Kiryung Lee , Yanjun Li , Kyong Hwan Jin , Jong Chul Ye

Sparse representations using overcomplete dictionaries have proved to be a powerful tool in many signal processing applications such as denoising, super-resolution, inpainting, compression or classification. The sparsity of the…

Machine Learning · Statistics 2018-03-01 Jeremy Aghaei Mazaheri , Elif Vural , Claude Labit , Christine Guillemot

Cellular differentiation is governed by gene regulatory networks, the high-dimensional stochastic biochemical systems that determine the transcriptional landscape and mediate cellular responses to signals and perturbations. Although…

Molecular Networks · Quantitative Biology 2026-04-29 Suryanarayana Maddu , Victor Chardès , Michael J. Shelley

Computational imaging is increasingly vital for a broad spectrum of applications, ranging from biological to material sciences. This includes applications where the object is known and sufficiently sparse, allowing it to be described with a…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Jacob Seifert , Yifeng Shao , Allard P. Mosk

Signal modeling lies at the core of numerous signal and image processing applications. A recent approach that has drawn considerable attention is sparse representation modeling, in which the signal is assumed to be generated as a…

Information Theory · Computer Science 2016-11-17 Tomer Peleg , Yonina C. Eldar , Michael Elad

This paper emphasizes the significance to jointly exploit the problem structure and the parameter structure, in the context of deep modeling. As a specific and interesting example, we describe the deep double sparsity encoder (DDSE), which…

Machine Learning · Computer Science 2016-10-04 Zhangyang Wang , Thomas S. Huang

Binary tomography is concerned with reconstructing a binary image from a very small number or other limited CT projection data. This problem itself not only possesses several medical imaging applications but also can be considered a model…

Image and Video Processing · Electrical Eng. & Systems 2022-08-24 Haytham A. Ali , Katsuya Fujii , Hiroyuki Kudo

Sparse dictionary learning (SDL) is a fundamental technique that is useful for many image processing tasks. As an example we consider here image recovery, where SDL can be cast as a nonsmooth optimization problem. For this kind of problems,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Mohammadsadegh Khoshghiaferezaee , Moritz Krauth , Shima Shabani , Michael Breuß

The problem of population recovery refers to estimating a distribution based on incomplete or corrupted samples. Consider a random poll of sample size $n$ conducted on a population of individuals, where each pollee is asked to answer $d$…

Statistics Theory · Mathematics 2020-04-30 Yury Polyanskiy , Ananda Theertha Suresh , Yihong Wu

Sparse graph recovery methods work well where the data follows their assumptions but often they are not designed for doing downstream probabilistic queries. This limits their adoption to only identifying connections among the input…

Machine Learning · Computer Science 2024-10-23 Harsh Shrivastava , Urszula Chajewska

In many practical applications such as direction-of-arrival (DOA) estimation and line spectral estimation, the sparsifying dictionary is usually characterized by a set of unknown parameters in a continuous domain. To apply the conventional…

Information Theory · Computer Science 2015-06-18 Jun Fang , Jing Li , Yanning Shen , Hongbin Li , Shaoqian Li

We report a flexible language-model based deep learning strategy, applied here to solve complex forward and inverse problems in protein modeling, based on an attention neural network that integrates transformer and graph convolutional…

Biomolecules · Quantitative Biology 2023-10-20 Markus J. Buehler

We frame the task of predicting a semantic labeling as a sparse reconstruction procedure that applies a target-specific learned transfer function to a generic deep sparse code representation of an image. This strategy partitions training…

Computer Vision and Pattern Recognition · Computer Science 2014-10-17 Michael Maire , Stella X. Yu , Pietro Perona