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Recent advancements in Digital Pathology (DP), particularly through artificial intelligence and Foundation Models, have underscored the importance of large-scale, diverse, and richly annotated datasets. Despite their critical role, publicly…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Dmitry Nechaev , Alexey Pchelnikov , Ekaterina Ivanova

Imaging has occupied a huge role in the management of patients, whether hospitalized or not. Depending on the patients clinical problem, a variety of imaging modalities were available for use. This gave birth of the annotation of medical…

Computer Vision and Pattern Recognition · Computer Science 2013-07-04 Mouhamed Gaith Ayadi , Riadh Bouslimi , Jalel Akaichi

The computer-aided analysis of medical scans is a longstanding goal in the medical imaging field. Currently, deep learning has became a dominant methodology for supporting pathologists and radiologist. Deep learning algorithms have been…

Machine Learning · Computer Science 2017-12-06 Jakub M. Tomczak , Maximilian Ilse , Max Welling

Artificial Intelligence (AI) has great potential to improve health outcomes by training systems on vast digitized clinical datasets. Computational Pathology, with its massive amounts of microscopy image data and impact on diagnostics and…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Gabriele Campanella , Eugene Fluder , Jennifer Zeng , Chad Vanderbilt , Thomas J. Fuchs

Continual learning is rapidly emerging as a key focus in computer vision, aiming to develop AI systems capable of continuous improvement, thereby enhancing their value and practicality in diverse real-world applications. In healthcare,…

Digital pathology has gained significant traction in modern healthcare systems. This shift from optical microscopes to digital imagery brings with it the potential for improved diagnosis, efficiency, and the integration of AI tools into the…

Image and Video Processing · Electrical Eng. & Systems 2024-02-16 Mark Eastwood , John Pocock , Mostafa Jahanifar , Adam Shephard , Skiros Habib , Ethar Alzaid , Abdullah Alsalemi , Jan Lukas Robertus , Nasir Rajpoot , Shan Raza , Fayyaz Minhas

Over the past decade, artificial intelligence (AI) methods in pathology have advanced substantially. However, integration into routine clinical practice has been slow due to numerous challenges, including technical and regulatory hurdles in…

Accurate disease diagnosis depends on effective collaboration between medical specialties, yet departments often use distinct data systems and proprietary formats. This heterogeneity hinders joint analysis and integration of complementary…

Controllable pathology image synthesis requires reliable regulation of spatial layout, tissue morphology, and semantic detail. However, existing text-guided diffusion models offer only coarse global control and lack the ability to enforce…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Yuntao Shou , Xiangyong Cao , Qian Zhao , Deyu Meng

The emergence of large multimodal models (LMMs) has brought significant advancements to pathology. Previous research has primarily focused on separately training patch-level and whole-slide image (WSI)-level models, limiting the integration…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Yuxuan Sun , Yixuan Si , Chenglu Zhu , Xuan Gong , Kai Zhang , Pingyi Chen , Ye Zhang , Zhongyi Shui , Tao Lin , Lin Yang

Epistemic AI accelerates biomedical discovery by finding hidden connections in the network of biomedical knowledge. The Epistemic AI web-based software platform embodies the concept of knowledge mapping, an interactive process that relies…

Artificial Intelligence · Computer Science 2022-04-04 Da Chen Emily Koo , Heather Bowling , Kenneth Ashworth , David J. Heeger , Stefano Pacifico

Purpose: In this work, we present a collaboration to create a validation dataset of pathologist annotations for algorithms that process whole slide images (WSIs). We focus on data collection and evaluation of algorithm performance in the…

Advancing AI in computational pathology requires large, high-quality, and diverse datasets, yet existing public datasets are often limited in organ diversity, class coverage, or annotation quality. To bridge this gap, we introduce SPIDER…

Image and Video Processing · Electrical Eng. & Systems 2025-04-08 Dmitry Nechaev , Alexey Pchelnikov , Ekaterina Ivanova

Representation learning on electronic health records (EHRs) plays a vital role in downstream medical prediction tasks. Although natural language processing techniques, such as recurrent neural networks, and self-attention, have been adapted…

Artificial Intelligence · Computer Science 2026-01-12 Xueping Peng , Guodong Long , Tao Shen , Sen Wang , Chengqi Zhang , Allison Clarke , Clement Schlegel

Genomic data and biomedical imaging data are undergoing exponential growth. However, our understanding of the phenotype-genotype connection linking the two types of data is lagging behind. While there are many types of software that enable…

Genomics · Quantitative Biology 2013-01-09 Andrew T. Oberlin , Dominika A. Jurkovic , Mitchell F. Balish , Iddo Friedberg

Pathology has played a crucial role in the diagnosis and evaluation of patient tissue samples obtained from surgeries and biopsies for many years. The advent of Whole Slide Scanners and the development of deep learning technologies have…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Mieko Ochi , Daisuke Komura , Shumpei Ishikawa

Deep learning based automated pathological diagnosis has markedly improved diagnostic efficiency and reduced variability between observers, yet its clinical adoption remains limited by opaque model decisions and a lack of traceable…

Accessing high-quality, open-access dermatopathology image datasets for learning and cross-referencing is a common challenge for clinicians and dermatopathology trainees. To establish a comprehensive open-access dermatopathology dataset for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Ziyang Xu , Mingquan Lin , Yiliang Zhou , Zihan Xu , Seth J. Orlow , Shane A. Meehan , Alexandra Flamm , Ata S. Moshiri , Yifan Peng

Advances in AI have introduced several strong models in computational pathology to usher it into the era of multi-modal diagnosis, analysis, and interpretation. However, the current pathology-specific visual language models still lack…

Semantic segmentations of pathological entities have crucial clinical value in computational pathology workflows. Foundation models, such as the Segment Anything Model (SAM), have been recently proposed for universal use in segmentation…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Jingwei Zhang , Ke Ma , Saarthak Kapse , Joel Saltz , Maria Vakalopoulou , Prateek Prasanna , Dimitris Samaras