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Classical learning theory suggests that the optimal generalization performance of a machine learning model should occur at an intermediate model complexity, with simpler models exhibiting high bias and more complex models exhibiting high…

Machine Learning · Statistics 2020-11-09 Ben Adlam , Jeffrey Pennington

Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by the death of dopaminergic neurons, leading to various movement disorder symptoms. Early diagnosis of PD is crucial to prevent adverse effects, yet…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Nabil Daiyan , Md Rakibul Haque

Polarization images provide rich physical information that is fundamentally absent from standard RGB images, benefiting a wide range of computer vision applications such as reflection separation and material classification. However, the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Beibei Lin , Zifeng Yuan , Tingting Chen

Machine learning has recently been applied and deployed at several light source facilities in the domain of Accelerator Physics. We introduce an approach based on machine learning to produce a fast-executing model that predicts the…

Accelerator Physics · Physics 2022-01-19 Ryan Sheppard , Cameron Baribeau , Tor Pedersen , Mark Boland , Drew Bertwistle

Purpose: Ultrasound is the most commonly used medical imaging modality for diagnosis and screening in clinical practice. Due to its safety profile, noninvasive nature and portability, ultrasound is the primary imaging modality for fetal…

Image and Video Processing · Electrical Eng. & Systems 2024-01-19 Sonit Singh , Gordon Stevenson , Brendan Mein , Alec Welsh , Arcot Sowmya

Nonsequential two-photon ionization of inner-shell $np$ subshell of neutral atoms by circularly polarized light is investigated. Detection of subsequent fluorescence as a signature of the process is proposed and the dependence of…

Atomic Physics · Physics 2019-07-17 J. Hofbrucker , A. V. Volotka , S. Fritzsche

Live-cell imaging of multiple subcellular structures is essential for understanding subcellular dynamics. However, the conventional multi-color sequential fluorescence microscopy suffers from significant imaging delays and limited number of…

Subcellular Processes · Quantitative Biology 2025-01-13 Mingyang Chen , Luhong Jin , Xuwei Xuan , Defu Yang , Yun Cheng , Ju Zhang

Deep learning advances have revolutionized automated digital pathology analysis. However, differences in staining protocols and imaging conditions can introduce significant color variability. In deep learning, such color inconsistency often…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Tianyue Xu , Yanlin Wu , Abhai K. Tripathi , Matthew M. Ippolito , Benjamin D. Haeffele

Fluorescence labeling is the standard approach to reveal cellular structures and other subcellular constituents for microscopy images. However, this invasive procedure may perturb or even kill the cells and the procedure itself is highly…

Image and Video Processing · Electrical Eng. & Systems 2024-06-25 Han Liu , Hao Li , Jiacheng Wang , Yubo Fan , Zhoubing Xu , Ipek Oguz

Scanning electron microscopy with polarization analysis is a powerful lab-based magnetic imaging technique offering parallel imaging of multiple magnetization components and a very high spatial resolution. However, one drawback of the…

Instrumentation and Detectors · Physics 2018-08-22 Daniel Schönke , Andreas Oelsner , Pascal Krautscheid , Robert M. Reeve , Mathias Kläui

Current pathology workflow involves staining of thin tissue slices, which otherwise would be transparent, followed by manual investigation under the microscope by a trained pathologist. While the hematoxylin and eosin (H&E) stain is…

Medical Physics · Physics 2021-05-04 Jingfang "Kelly" Zhang , Yuchen R. He , Nahil Sobh , Gabriel Popescu

In recent years, the research landscape of machine learning in medical imaging has changed drastically from supervised to semi-, weakly- or unsupervised methods. This is mainly due to the fact that ground-truth labels are time-consuming and…

Image and Video Processing · Electrical Eng. & Systems 2021-10-04 Turkay Kart , Wenjia Bai , Ben Glocker , Daniel Rueckert

A core aim of neurocritical care is to prevent secondary brain injury. Spreading depolarizations (SDs) have been identified as an important independent cause of secondary brain injury. SDs are usually detected using invasive…

Signal Processing · Electrical Eng. & Systems 2026-05-19 Yinzhe Wu , Sharon Jewell , Xiaodan Xing , Yang Nan , Anthony J. Strong , Guang Yang , Martyn G. Boutelle

The polarization state of the optical electromagnetic field lying several nanometers above complex dielectric structures reveals the intricate light-matter interaction that occurs in this near-field zone. This information can only be…

Objectives. Sustainable management of plant diseases is an open challenge which has relevant economic and environmental impact. Optimal strategies rely on human expertise for field scouting under favourable conditions to assess the current…

Computer Vision and Pattern Recognition · Computer Science 2021-12-22 Alessandro Benfenati , Paola Causin , Roberto Oberti , Giovanni Stefanello

Wavefront-shaping is a promising approach for imaging fluorescent targets deep inside scattering tissue despite strong aberrations. It enables focusing an incoming illumination into a single spot inside tissue, as well as correcting the…

Optics · Physics 2024-01-23 Dror Aizik , Anat Levin

To answer the existence of optimal swimmer learning/teaching strategies, this work introduces a two-level clustering in order to analyze temporal dynamics of motor learning in breaststroke swimming. Each level have been performed through…

Machine Learning · Statistics 2014-01-08 John Komar , Romain Hérault , Ludovic Seifert

Convolutional Neural Networks have demonstrated dermatologist-level performance in the classification of melanoma from skin lesion images, but prediction irregularities due to biases seen within the training data are an issue that should be…

Computer Vision and Pattern Recognition · Computer Science 2023-04-28 Peter J. Bevan , Amir Atapour-Abarghouei

Predictive modeling is useful but very challenging in biological image analysis due to the high cost of obtaining and labeling training data. For example, in the study of gene interaction and regulation in Drosophila embryogenesis, the…

Machine Learning · Computer Science 2020-10-21 Lei Cai , Zhengyang Wang , Rob Kulathinal , Sudhir Kumar , Shuiwang Ji

Videomicroscopy is a promising tool combined with machine learning for studying the early development of in vitro fertilized bovine embryos and assessing its transferability as soon as possible. We aim to predict the embryo transferability…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 Yasmine Hachani , Patrick Bouthemy , Elisa Fromont , Sylvie Ruffini , Ludivine Laffont , Alline de Paula Reis