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Label-free imaging has gained broad interest because of its potential to omit elaborate staining procedures which is especially relevant for in vivo use. Label-free multiphoton microscopy (MPM), for instance, exploits two-photon excitation…

How can we find interpretable, domain-appropriate models of natural phenomena given some complex, raw data such as images? Can we use such models to derive scientific insight from the data? In this paper, we propose some methods for…

Machine Learning · Computer Science 2024-02-06 Christopher J. Soelistyo , Alan R. Lowe

Polarized neutrons are a powerful probe to investigate magnetism in condensed matter on length scales from single atomic distances to micrometers. With the ongoing advancement of neutron optics, that allow to transport beams with increased…

Instrumentation and Detectors · Physics 2017-08-02 Jochen Stahn , Artur Glavic

Primary neuronal cultures have been widely used to study neuronal morphology, neurophysiology, neurodegenerative processes, and molecular mechanism of synaptic plasticity underlying learning and memory. Yet, the unique behavioral properties…

Image and Video Processing · Electrical Eng. & Systems 2020-08-04 Mikhail E. Kandel , Eunjae Kim , Young Jae Lee , Gregory Tracy , Hee Jung Chung , Gabriel Popescu

Polaritonic lattices offer a unique testbed for studying nonlinear driven-dissipative physics. They show qualitative changes of a steady state as a function of system parameters, which resemble non-equilibrium phase transitions. Unlike…

Mesoscale and Nanoscale Physics · Physics 2022-05-16 D. Zvyagintseva , H. Sigurdsson , V. K. Kozin , I. Iorsh , I. A. Shelykh , V. Ulyantsev , O. Kyriienko

The discovery of pulsars is of great significance in the field of physics and astronomy. As the astronomical equipment produces a large amount of pulsar data, an algorithm for automatically identifying pulsars becomes urgent. We propose a…

Instrumentation and Methods for Astrophysics · Physics 2021-12-08 ShiChuan Zhang , XiangCong Kong , YueYing Zhou , LingYao Chen , XiaoYing Zheng , Chun-Ling Xu , Bao-Qiang Lao , Tao An

This paper proposes a probabilistic approach for the detection and the tracking of particles in fluorescent time-lapse imaging. In the presence of a very noised and poor-quality data, particles and trajectories can be characterized by an a…

Computer Vision and Pattern Recognition · Computer Science 2017-04-04 Mariella Dimiccoli , Jean-Pascal Jacob , Lionel Moisan

Holography is a cornerstone characterisation and imaging technique that can be applied to the full electromagnetic spectrum, from X-rays to radio waves or even particles such as neutrons. The key property in all these holographic approaches…

Quantum Physics · Physics 2021-01-12 Hugo Defienne , Bienvenu Ndagano , Ashley Lyons , Daniele Faccio

Plastic waste in aquatic environments poses severe risks to marine life and human health. Autonomous robots can be utilized to collect floating waste, but they require accurate object identification capability. While deep learning has been…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Luis Felipe Wolf Batista , Salim Khazem , Mehran Adibi , Seth Hutchinson , Cedric Pradalier

After a surge in popularity of supervised Deep Learning, the desire to reduce the dependence on curated, labelled data sets and to leverage the vast quantities of unlabelled data available recently triggered renewed interest in unsupervised…

Machine Learning · Computer Science 2020-09-21 Lorijn Zaadnoordijk , Tarek R. Besold , Rhodri Cusack

Deep learning offers powerful tools for anticipating tipping points in complex systems, yet its potential for detecting flickering (noise-driven switching between coexisting stable states) remains unexplored. Flickering is a hallmark of…

Machine Learning · Computer Science 2025-09-08 Yazdan Babazadeh Maghsoodlo , Madhur Anand , Chris T. Bauch

Sample-induced aberrations and optical imperfections limit the resolution of fluorescence microscopy. Phase diversity is a powerful technique that leverages complementary phase information in sequentially acquired images with deliberately…

The polarisation of cells and tissues is fundamental for tissue morphogenesis during biological development and regeneration. A deeper understanding of biological polarity pattern formation can be gained from the consideration of pattern…

Cell Behavior · Quantitative Biology 2017-10-23 Karl B. Hoffmann , Anja Voss-Böhme , Jochen C. Rink , Lutz Brusch

Since specular reflection often exists in the real captured images and causes deviation between the recorded color and intrinsic color, specular reflection separation can bring advantages to multiple applications that require consistent…

Computer Vision and Pattern Recognition · Computer Science 2022-01-26 Sijia Wen , Yingqiang Zheng , Feng Lu

We demonstrate the application of a two stage machine learning algorithm that enables to correlate the electrical signals from a GaAs$_x$N$_{1-x}$ circular polarimeter with the intensity, degree of circular polarization and handedness of an…

Other Condensed Matter · Physics 2022-03-23 A. Aguirre-Perez , R. S. Joshya , H. Carrère , X. Marie , T. Amand , A. Balocchi , A. Kunold

The success of deep learning in computer vision is rooted in the ability of deep networks to scale up model complexity as demanded by challenging visual tasks. As complexity is increased, so is the need for large amounts of labeled data to…

Computer Vision and Pattern Recognition · Computer Science 2017-08-22 Gustav Larsson

Fetal motion discernment utilizing spectral images extracted from accelerometric data incident on pregnant mothers abdomen has gained substantial attention in the state-of-the-art research. It is an essential practice to avoid adverse…

Accurate assessment of human epidermal growth factor receptor 2 (HER2) expression is critical for breast cancer diagnosis, prognosis, and therapy selection; yet, most existing digital HER2 scoring methods rely on bulky and expensive optical…

Medical Physics · Physics 2026-01-27 Che-Yung Shen , Xilin Yang , Yuzhu Li , Leon Lenk , Aydogan Ozcan

We present a fast and accurate analytical method for fluorescence lifetime imaging microscopy (FLIM) using the extreme learning machine (ELM). We used extensive metrics to evaluate ELM and existing algorithms. First, we compared these…

Biological Physics · Physics 2022-03-28 Zhenya Zang , Dong Xiao , Quan Wang , Zinuo Li , Wujun Xie , Yu Chen , David Day Uei Li

Electron microscopy is widely used to explore defects in crystal structures, but human detecting of defects is often time-consuming, error-prone, and unreliable, and is not scalable to large numbers of images or real-time analysis. In this…

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