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The increase in availability of longitudinal electronic health record (EHR) data is leading to improved understanding of diseases and discovery of novel phenotypes. The majority of clustering algorithms focus only on patient trajectories,…

Machine Learning · Computer Science 2021-11-12 Oliver Carr , Avelino Javer , Patrick Rockenschaub , Owen Parsons , Robert Dürichen

We provide an accessible description of a peer-reviewed generalizable causal machine learning pipeline to (i) discover latent causal sources of large-scale electronic health records observations, and (ii) quantify the source causal effects…

Machine Learning · Computer Science 2025-11-03 Marco Barbero-Mota , Eric V. Strobl , John M. Still , William W. Stead , Thomas A. Lasko

Objective: This paper gives context on recent literature regarding the development of digital personal health libraries (PHL) and provides insights into the potential application of consumer health informatics in diverse clinical…

Digital Libraries · Computer Science 2020-06-23 Huitong Ding , Chi Zhang , Ning An , Lingling Zhang , Ning Xie , Gil Alterovitz

Deep learning-based modeling of multimodal Electronic Health Records (EHRs) has become an important approach for clinical diagnosis and risk prediction. However, due to diverse clinical workflows and privacy constraints, raw EHRs are…

Machine Learning · Computer Science 2026-04-09 Bohao Li , Tao Zou , Junchen Ye , Yan Gong , Bowen Du

The treatment effects of medications play a key role in guiding medical prescriptions. They are usually assessed with randomized controlled trials (RCTs), which are expensive. Recently, large-scale electronic health records (EHRs) have…

Machine Learning · Statistics 2019-08-20 Linying Zhang , Yixin Wang , Anna Ostropolets , Jami J. Mulgrave , David M. Blei , George Hripcsak

Multimodal Large Language Models (MLLMs) have shown transformative potential in medical applications, yet their performance is hindered by conventional data curation strategies that rely on coarse-grained partitioning by modality or…

Computation and Language · Computer Science 2026-04-29 Jianghang Lin , Haihua Yang , Deli Yu , Kai Wu , Kai Ye , Jinghao Lin , Zihan Wang , Yuhang Wu , Liujuan Cao

Electronic Health Records (EHR) are data generated during routine clinical care. EHR offer researchers unprecedented phenotypic breadth and depth and have the potential to accelerate the pace of precision medicine at scale. A main EHR…

Quantitative Methods · Quantitative Biology 2017-04-28 Vaclav Papez , Spiros Denaxas , Harry Hemingway

Dynamic predictive modelling using electronic health record (EHR) data has gained significant attention in recent years. The reliability and trustworthiness of such models depend heavily on the quality of the underlying data, which is, in…

Fusing multi-modal data can improve the performance of deep learning models. However, missing modalities are common for medical data due to patients' specificity, which is detrimental to the performance of multi-modal models in…

Image and Video Processing · Electrical Eng. & Systems 2023-09-28 Muyu Wang , Shiyu Fan , Yichen Li , Hui Chen

Given the growing complexity of healthcare data over the last several years, using machine learning techniques like Deep Neural Network (DNN) models has gained increased appeal. In order to extract hidden patterns and other valuable…

Machine Learning · Computer Science 2023-10-03 Hasan Hejbari Zargar , Saha Hejbari Zargar , Raziye Mehri

Cancer research is increasingly driven by the integration of diverse data modalities, spanning from genomics and proteomics to imaging and clinical factors. However, extracting actionable insights from these vast and heterogeneous datasets…

The widespread application of Electronic Health Records (EHR) data in the medical field has led to early successes in disease risk prediction using deep learning methods. These methods typically require extensive data for training due to…

Machine Learning · Computer Science 2024-11-28 Shibo Li , Hengliang Cheng , Weihua Li

The use of machine learning (ML) for cancer staging through medical image analysis has gained substantial interest across medical disciplines. When accompanied by the innovative federated learning (FL) framework, ML techniques can further…

Machine Learning · Computer Science 2024-10-10 Kasra Borazjani , Naji Khosravan , Leslie Ying , Seyyedali Hosseinalipour

Recent advancements in multimodal machine learning have empowered the development of accurate and robust AI systems in the medical domain, especially within centralized database systems. Simultaneously, Federated Learning (FL) has…

Increasing volume of Electronic Health Records (EHR) in recent years provides great opportunities for data scientists to collaborate on different aspects of healthcare research by applying advanced analytics to these EHR clinical data. A…

Machine Learning · Computer Science 2019-09-23 Najibesadat Sadati , Milad Zafar Nezhad , Ratna Babu Chinnam , Dongxiao Zhu

The widespread digitization of patient data via electronic health records (EHRs) has created an unprecedented opportunity to use machine learning algorithms to better predict disease risk at the patient level. Although predictive models…

Biomedical data is inherently multimodal, consisting of electronic health records, medical imaging, digital pathology, genome sequencing, wearable sensors, and more. The application of artificial intelligence tools to these multifaceted…

Machine Learning · Computer Science 2024-08-26 Shentong Mo , Paul Pu Liang

Augmentation of disease diagnosis and decision-making in healthcare with machine learning algorithms is gaining much impetus in recent years. In particular, in the current epidemiological situation caused by COVID-19 pandemic, swift and…

Computers and Society · Computer Science 2021-02-23 Leopold Franz , Yash Raj Shrestha , Bibek Paudel

Large Language Models (LLMs) have demonstrated remarkable performance across various domains, including healthcare. However, their ability to effectively represent structured non-textual data, such as the alphanumeric medical codes used in…

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda