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Organic Solar Cells (OSCs) are a promising technology for sustainable energy production. However, the identification of molecules with desired OSC properties typically involves laborious experimental research. To accelerate progress in the…

Machine Learning · Computer Science 2024-12-13 Zhihao Ding , Ting Zhang , Yiran Li , Jieming Shi , Chen Jason Zhang

How to obtain informative representations of molecules is a crucial prerequisite in AI-driven drug design and discovery. Recent researches abstract molecules as graphs and employ Graph Neural Networks (GNNs) for molecular representation…

Biomolecules · Quantitative Biology 2020-10-30 Yu Rong , Yatao Bian , Tingyang Xu , Weiyang Xie , Ying Wei , Wenbing Huang , Junzhou Huang

Recent advancements in computational chemistry have leveraged the power of trans-former-based language models, such as MoLFormer, pre-trained using a vast amount of simplified molecular-input line-entry system (SMILES) sequences, to…

Biomolecules · Quantitative Biology 2024-11-05 Tianhao Peng , Yuchen Li , Xuhong Li , Jiang Bian , Zeke Xie , Ning Sui , Shahid Mumtaz , Yanwu Xu , Linghe Kong , Haoyi Xiong

Pre-trained Language Models have emerged as promising tools for predicting molecular properties, yet their development is in its early stages, necessitating further research to enhance their efficacy and address challenges such as…

Machine Learning · Computer Science 2023-10-24 Eduardo Soares , Akihiro Kishimoto , Emilio Vital Brazil , Seiji Takeda , Hiroshi Kajino , Renato Cerqueira

In this study, we present ScoreFormer, a novel graph transformer model designed to accurately predict molecular docking scores, thereby optimizing high-throughput virtual screening (HTVS) in drug discovery. The architecture integrates…

Machine Learning · Computer Science 2024-06-26 Álvaro Ciudad , Adrián Morales-Pastor , Laura Malo , Isaac Filella-Mercè , Victor Guallar , Alexis Molina

Recent advances in applying Graph Neural Networks (GNNs) to molecular science have showcased the power of learning three-dimensional (3D) structure representations with GNNs. However, most existing GNNs suffer from the limitations of…

Biomolecules · Quantitative Biology 2023-11-21 Shuo Zhang , Yang Liu , Lei Xie

Accurate molecular property prediction is central to drug discovery, catalysis, and process design, yet real-world applications are often limited by small datasets. Molecular foundation models provide a promising direction by learning…

Machine Learning · Computer Science 2026-04-21 Karim K. Ben Hicham , Jan G. Rittig , Martin Grohe , Alexander Mitsos

Nucleic acid-based drugs like aptamers have recently demonstrated great therapeutic potential. However, experimental platforms for aptamer screening are costly, and the scarcity of labeled data presents a challenge for supervised methods to…

Biomolecules · Quantitative Biology 2024-11-05 Tinglin Huang , Zhenqiao Song , Rex Ying , Wengong Jin

Accurate prediction of molecular properties is essential in drug discovery and related fields. However, existing graph neural networks (GNNs) often struggle to simultaneously capture both local and global molecular structures. In this work,…

Machine Learning · Computer Science 2025-08-26 XiaYu Liu , Chao Fan , Yang Liu , Hou-biao Li

As a core technology of Intelligent Transportation System, traffic flow prediction has a wide range of applications. The fundamental challenge in traffic flow prediction is to effectively model the complex spatial-temporal dependencies in…

Machine Learning · Computer Science 2024-03-08 Jiawei Jiang , Chengkai Han , Wayne Xin Zhao , Jingyuan Wang

Transformers have demonstrated remarkable performance in natural language processing and computer vision. However, existing vision Transformers struggle to learn from limited medical data and are unable to generalize on diverse medical…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Yunhe Gao , Mu Zhou , Di Liu , Zhennan Yan , Shaoting Zhang , Dimitris N. Metaxas

Learning from limited data is challenging because data scarcity leads to a poor generalization of the trained model. A classical global pooled representation will probably lose useful local information. Many few-shot learning methods have…

Computer Vision and Pattern Recognition · Computer Science 2023-05-11 Haoxing Chen , Huaxiong Li , Yaohui Li , Chunlin Chen

Molecular representation is a critical element in our understanding of the physical world and the foundation for modern molecular machine learning. Previous molecular machine learning models have employed strings, fingerprints, global…

Machine Learning · Computer Science 2025-05-28 Daniil A. Boiko , Thiago Reschützegger , Benjamin Sanchez-Lengeling , Samuel M. Blau , Gabe Gomes

Determining protein structures at an atomic level remains a significant challenge in structural biology. We introduce $\texttt{RecCrysFormer}$, a hybrid model that exploits the strengths of transformers with the aim of integrating…

Quantitative Methods · Quantitative Biology 2026-01-30 Tom Pan , Evan Dramko , Mitchell D. Miller , George N. Phillips , Anastasios Kyrillidis

Large pre-trained models with their numerous model parameters and extensive training datasets have shown excellent performance in various tasks. Many publicly available medical image datasets do not have a sufficient amount of data so there…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Jianhao Xie , Ziang Zhang , Guibo Luo , Yuesheng Zhu

Predicting electronic band structures from crystal structures is crucial for understanding structure-property correlations in materials science. First-principles approaches are accurate but computationally intensive. Recent years, machine…

Materials Science · Physics 2025-10-02 Weiyi Gong , Tao Sun , Hexin Bai , Jeng-Yuan Tsai , Haibin Ling , Qimin Yan

We present a new table structure recognition (TSR) approach, called TSRFormer, to robustly recognizing the structures of complex tables with geometrical distortions from various table images. Unlike previous methods, we formulate table…

Computer Vision and Pattern Recognition · Computer Science 2022-08-10 Weihong Lin , Zheng Sun , Chixiang Ma , Mingze Li , Jiawei Wang , Lei Sun , Qiang Huo

Transforming road network data into vector representations using deep learning has proven effective for road network analysis. However, urban road networks' heterogeneous and hierarchical nature poses challenges for accurate representation…

Artificial Intelligence · Computer Science 2025-09-10 Jian Yang , Jiahui Wu , Li Fang , Hongchao Fan , Bianying Zhang , Huijie Zhao , Guangyi Yang , Rui Xin , Xiong You

In-context learning allows large models to adapt to new tasks from a few demonstrations, but it has shown limited success in molecular design. Existing databases such as ChEMBL contain molecular properties spanning millions of biological…

Machine Learning · Computer Science 2025-10-13 Gang Liu , Jie Chen , Yihan Zhu , Michael Sun , Tengfei Luo , Nitesh V Chawla , Meng Jiang

Hyperspectral object tracking using snapshot mosaic cameras is emerging as it provides enhanced spectral information alongside spatial data, contributing to a more comprehensive understanding of material properties. Using transformers,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Shaheer Mohamed , Tharindu Fernando , Sridha Sridharan , Peyman Moghadam , Clinton Fookes
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