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Multitask learning, i.e. learning several tasks at once with the same neural network, can improve performance in each of the tasks. Designing deep neural network architectures for multitask learning is a challenge: There are many ways to…

Neural and Evolutionary Computing · Computer Science 2018-04-19 Jason Liang , Elliot Meyerson , Risto Miikkulainen

The field development optimization (FDO) problem represents a challenging mixed-integer nonlinear programming (MINLP) problem in which we seek to obtain the number of wells, their type, location, and drilling sequence that maximizes an…

Signal Processing · Electrical Eng. & Systems 2022-07-22 Yusuf Nasir

Deep Learning has become interestingly popular in computer vision, mostly attaining near or above human-level performance in various vision tasks. But recent work has also demonstrated that these deep neural networks are very vulnerable to…

Machine Learning · Computer Science 2020-12-09 Shashi Kant Gupta

The transformation towards renewable energy and feedstock supply in the chemical industry requires new conceptual process design approaches. Recently, breakthroughs in artificial intelligence offer opportunities to accelerate this…

Machine Learning · Computer Science 2023-08-16 Qinghe Gao , Artur M. Schweidtmann

Dynamic Algorithm Configuration (DAC) studies the efficient identification of control policies for parameterized optimization algorithms. Numerous studies leverage Reinforcement Learning (RL) to address DAC challenges; however, applying RL…

Machine Learning · Computer Science 2026-04-03 Tai Nguyen , Phong Le , André Biedenkapp , Carola Doerr , Nguyen Dang

Reinforcement Learning (RL) has demonstrated significant potential in certain real-world industrial applications, yet its broader deployment remains limited by inherent challenges such as sample inefficiency and unstable learning dynamics.…

Machine Learning · Computer Science 2025-07-03 Tom Maus , Asma Atamna , Tobias Glasmachers

Revenue-optimal auction design is a challenging problem with significant theoretical and practical implications. Sequential auction mechanisms, known for their simplicity and strong strategyproofness guarantees, are often limited by…

Computer Science and Game Theory · Computer Science 2024-07-12 Sai Srivatsa Ravindranath , Zhe Feng , Di Wang , Manzil Zaheer , Aranyak Mehta , David C. Parkes

The phase-ordering problem of modern compilers has received a lot of attention from the research community over the years, yet remains largely unsolved. Various optimization sequences exposed to the user are manually designed by compiler…

Machine Learning · Computer Science 2020-10-19 Rahim Mammadli , Ali Jannesari , Felix Wolf

Fabricating neural models for a wide range of mobile devices demands for a specific design of networks due to highly constrained resources. Both evolution algorithms (EA) and reinforced learning methods (RL) have been dedicated to solve…

Neural and Evolutionary Computing · Computer Science 2019-01-17 Xiangxiang Chu , Bo Zhang , Ruijun Xu , Hailong Ma

Current Deep Reinforcement Learning algorithms still heavily rely on handcrafted neural network architectures. We propose a novel approach to automatically find strong topologies for continuous control tasks while only adding a minor…

Machine Learning · Computer Science 2020-02-28 Jörg K. H. Franke , Gregor Köhler , Noor Awad , Frank Hutter

In the era of smart manufacturing and Industry 4.0, the refining industry is evolving towards large-scale integration and flexible production systems. In response to these new demands, this paper presents a novel optimization framework for…

Systems and Control · Electrical Eng. & Systems 2025-04-14 Zhouchang Li , Runze Lin , Hongye Su , Lei Xie

Directed evolution is an iterative laboratory process of designing proteins with improved function by iteratively synthesizing new protein variants and evaluating their desired property with expensive and time-consuming biochemical…

Machine Learning · Computer Science 2025-09-08 Matouš Soldát , Jiří Kléma

In biology, predicting RNA secondary structures plays a vital role in determining its physical and chemical properties. Although we have powerful energy models to predict them as well as parametric analysis to understand the models…

Biomolecules · Quantitative Biology 2023-05-01 Doan Dai Nguyen

Modern deep architectures often rely on large-scale datasets, but training on these datasets incurs high computational and storage overhead. Real-world datasets often contain substantial redundancies, prompting the need for more…

Machine Learning · Computer Science 2025-06-27 Suorong Yang , Peijia Li , Furao Shen , Jian Zhao

The design of biological systems is hindered by uncertainty arising from both intrinsic stochasticity of biomolecular reactions and variability across laboratory or experimental conditions. In this work, we present a sequential framework to…

Machine Learning · Computer Science 2026-05-08 Michal Kobiela , Diego A. Oyarzún , Michael U. Gutmann

In this study, we analyze and compare the performance of state-of-the-art deep reinforcement learning algorithms for solving the supply chain inventory management problem. This complex sequential decision-making problem consists of…

Machine Learning · Computer Science 2025-01-07 Francesco Stranieri , Fabio Stella

We study reinforcement learning (RL) in high dimensional episodic Markov decision processes (MDP). We consider value-based RL when the optimal Q-value is a linear function of d-dimensional state-action feature representation. For instance,…

Artificial Intelligence · Computer Science 2019-09-10 Kamyar Azizzadenesheli , Animashree Anandkumar

In distributed optimization, the practical problem-solving performance is essentially sensitive to algorithm selection, parameter setting, problem type and data pattern. Thus, it is often laborious to acquire a highly efficient method for a…

Optimization and Control · Mathematics 2024-01-04 Daokuan Zhu , Tianqi Xu , Jie Lu

RNA is a fundamental class of biomolecules that mediate a large variety of molecular processes within the cell. Computational algorithms can be of great help in the understanding of RNA structure-function relationship. One of the main…

Biomolecules · Quantitative Biology 2015-02-20 Sandro Bottaro , Francesco Di Palma , Giovanni Bussi

We study the use of randomized value functions to guide deep exploration in reinforcement learning. This offers an elegant means for synthesizing statistically and computationally efficient exploration with common practical approaches to…

Machine Learning · Statistics 2019-09-25 Ian Osband , Benjamin Van Roy , Daniel Russo , Zheng Wen