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Heterogeneous molecular entities and their interactions, commonly depicted as a network, are crucial for advancing our systems-level understanding of biology. With recent advancements in high-throughput data generation and a significant…

Quantitative Methods · Quantitative Biology 2026-03-18 Kishan KC , Rui Li , Paribesh Regmi , Anne R. Haake

Bayesian inference on structured models typically relies on the ability to infer posterior distributions of underlying hidden variables. However, inference in implicit models or complex posterior distributions is hard. A popular tool for…

Machine Learning · Statistics 2016-12-16 Theofanis Karaletsos

In this paper, we develop a graphical modeling framework for the inference of networks across multiple sample groups and data types. In medical studies, this setting arises whenever a set of subjects, which may be heterogeneous due to…

Real-world clinical problems are often characterized by multimodal data, usually associated with incomplete views and limited sample sizes in their cohorts, posing significant limitations for machine learning algorithms. In this work, we…

The analysis of diffusion processes in real-world propagation scenarios often involves estimating variables that are not directly observed. These hidden variables include parental relationships, the strengths of connections between nodes,…

Social and Information Networks · Computer Science 2016-05-12 Shohreh Shaghaghian , Mark Coates

In recent times, neural networks have become a powerful tool for the analysis of complex and abstract data models. However, their introduction intrinsically increases our uncertainty about which features of the analysis are model-related…

Machine Learning · Statistics 2020-11-09 Tom Charnock , Laurence Perreault-Levasseur , François Lanusse

Data describing human interactions often suffer from incomplete sampling of the underlying population. As a consequence, the study of contagion processes using data-driven models can lead to a severe underestimation of the epidemic risk.…

Physics and Society · Physics 2015-11-19 Mathieu Génois , Christian L. Vestergaard , Ciro Cattuto , Alain Barrat

Bayesian graphical models are powerful tools to infer complex relationships in high dimension, yet are often fraught with computational and statistical challenges. If exploited in a principled way, the increasing information collected…

Methodology · Statistics 2024-03-15 Xiaoyue Xi , Hélène Ruffieux

When designing control strategies for an infectious disease it is critical to identify the key pathways of transmission. Data on infected hosts - when they were born, where they lived and with whom they interacted - can help infer sources…

Quantitative Methods · Quantitative Biology 2026-03-27 Anthony J Wood , Aeron R Sanchez , Rowland R Kao

The rapid spread of rumors on social media has posed significant challenges to maintaining public trust and information integrity. Since an information cascade process is essentially a propagation tree, recent rumor detection models…

Social and Information Networks · Computer Science 2025-07-28 Wei Jiang , Tong Chen , Xinyi Gao , Wentao Zhang , Lizhen Cui , Hongzhi Yin

Graph convolutional neural networks (GCNN) have numerous applications in different graph based learning tasks. Although the techniques obtain impressive results, they often fall short in accounting for the uncertainty associated with the…

Machine Learning · Computer Science 2019-11-13 Soumyasundar Pal , Florence Regol , Mark Coates

This paper studies the problem of distributed classification with a network of heterogeneous agents. The agents seek to jointly identify the underlying target class that best describes a sequence of observations. The problem is first…

Artificial Intelligence · Computer Science 2020-11-24 James Z. Hare , Cesar A. Uribe , Lance Kaplan , Ali Jadbabaie

Since the onset of the COVID-19 pandemic, there has been a growing interest in studying epidemiological models. Traditional mechanistic models mathematically describe the transmission mechanisms of infectious diseases. However, they often…

Machine Learning · Computer Science 2024-09-10 Zewen Liu , Guancheng Wan , B. Aditya Prakash , Max S. Y. Lau , Wei Jin

Infectious diseases pose significant human and economic burdens. Accurately forecasting disease incidence can enable public health agencies to respond effectively to existing or emerging diseases. Despite progress in the field, developing…

Machine Learning · Computer Science 2024-09-04 Michael Morris

We consider the spread of infectious disease through contact networks of Configuration Model type. We assume that the disease spreads through contacts and infected individuals recover into an immune state. We discuss a number of existing…

Populations and Evolution · Quantitative Biology 2014-03-11 Joel C Miller , Istvan Z Kiss

Causal discovery and inference from observational data is an essential problem in statistics posing both modeling and computational challenges. These are typically addressed by imposing strict assumptions on the joint distribution such as…

Machine Learning · Statistics 2024-02-20 Enrico Giudice , Jack Kuipers , Giusi Moffa

We propose a generative model and an inference scheme for epidemic processes on dynamic, adaptive contact networks. Network evolution is formulated as a link-Markovian process, which is then coupled to an individual-level stochastic SIR…

Methodology · Statistics 2020-04-07 Fan Bu , Allison E. Aiello , Jason Xu , Alexander Volfovsky

We present a new inference method based on approximate Bayesian computation for estimating parameters governing an entire network based on link-traced samples of that network. To do this, we first take summary statistics from an observed…

Computation · Statistics 2017-01-17 Jack Davis , Steven K. Thompson

A novel unified Bayesian framework for network detection is developed, under which a detection algorithm is derived based on random walks on graphs. The algorithm detects threat networks using partial observations of their activity, and is…

Social and Information Networks · Computer Science 2014-09-09 Steven T. Smith , Edward K. Kao , Kenneth D. Senne , Garrett Bernstein , Scott Philips

We consider the problem of diagnosing faults in a system represented by a Bayesian network, where diagnosis corresponds to recovering the most likely state of unobserved nodes given the outcomes of tests (observed nodes). Finding an optimal…

Artificial Intelligence · Computer Science 2012-07-09 Alice X. Zheng , Irina Rish , Alina Beygelzimer