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Single-cell multi-view clustering enables the exploration of cellular heterogeneity within the same cell from different views. Despite the development of several multi-view clustering methods, two primary challenges persist. Firstly, most…

Genomics · Quantitative Biology 2023-11-30 Dayu Hu , Zhibin Dong , Ke Liang , Jun Wang , Siwei Wang , Xinwang Liu

In drug discovery, it is vital to confirm the predictions of pharmaceutical properties from computational models using costly wet-lab experiments. Hence, obtaining reliable uncertainty estimates is crucial for prioritizing drug molecules…

Machine Learning · Computer Science 2023-10-19 Siddhartha Laghuvarapu , Zhen Lin , Jimeng Sun

In order to study 4-body atomic collisions such as excitation-ionization, transfer with target excitation, and double electron capture, the calculation of a nine-dimensional numerical integral is often required. This calculation can become…

Computational Physics · Physics 2013-05-09 A. L. Harris

Monocular depth estimation (MDE) is a challenging task in computer vision, often hindered by the cost and scarcity of high-quality labeled datasets. We tackle this challenge using auxiliary datasets from related vision tasks for an…

Computer Vision and Pattern Recognition · Computer Science 2025-04-14 Alessio Quercia , Erenus Yildiz , Zhuo Cao , Kai Krajsek , Abigail Morrison , Ira Assent , Hanno Scharr

Identifying metabolic sites where cytochrome P450 enzymes metabolize small-molecule drugs is essential for drug discovery. Although existing computational approaches have been proposed for site-of-metabolism prediction, they typically…

Quantitative Methods · Quantitative Biology 2026-01-30 Hajung Kim , Eunha Lee , Sohyun Chung , Jueon Park , Seungheun Baek , Jaewoo Kang

This paper proposes a novel modulation and coding scheme (MCS) selection framework that integrates mutual information (MI) prediction based on vector similarity search (VSS) for massive multi-user multiple-input multiple-output orthogonal…

Signal Processing · Electrical Eng. & Systems 2026-03-30 Fuga Kobayashi , Takumi Takahashi , Shinsuke Ibi , Takanobu Doi , Kazushi Muraoka , Hideki Ochiai

The limited availability of annotations in small molecule datasets presents a challenge to machine learning models. To address this, one common strategy is to collaborate with additional auxiliary datasets. However, having more data does…

Biomolecules · Quantitative Biology 2023-11-10 Tinglin Huang , Ziniu Hu , Rex Ying

When confronted with a substance of unknown identity, researchers often perform mass spectrometry on the sample and compare the observed spectrum to a library of previously-collected spectra to identify the molecule. While popular, this…

Chemical Physics · Physics 2019-05-07 Jennifer N. Wei , David Belanger , Ryan P. Adams , D. Sculley

The concept of matching dependencies (mds) is recently pro- posed for specifying matching rules for object identification. Similar to the functional dependencies (with conditions), mds can also be applied to various data quality…

Databases · Computer Science 2009-06-13 Shaoxu Song , Lei Chen

Compound-Protein Interaction (CPI) prediction aims to predict the pattern and strength of compound-protein interactions for rational drug discovery. Existing deep learning-based methods utilize only the single modality of protein sequences…

Biomolecules · Quantitative Biology 2024-02-14 Lirong Wu , Yufei Huang , Cheng Tan , Zhangyang Gao , Bozhen Hu , Haitao Lin , Zicheng Liu , Stan Z. Li

Molecular sequence analysis is crucial for comprehending several biological processes, including protein-protein interactions, functional annotation, and disease classification. The large number of sequences and the inherently complicated…

Genomics · Quantitative Biology 2025-10-10 Sarwan Ali , Prakash Chourasia , Bipin Koirala , Murray Patterson

Automated breast cancer detection via computer vision techniques is challenging due to the complex nature of breast tissue, the subtle appearance of cancerous lesions, and variations in breast density. Mainstream techniques primarily focus…

Quantitative Methods · Quantitative Biology 2025-12-11 Noor Ul Huda Shah , Tanveer Hussain , Amr Ahmed , Yonghuai Liu , Usman Ali , Ardhendu Behera

In recent years dynamical modelling has been provided with a range of breakthrough methods to perform exact Bayesian inference. However it is often computationally unfeasible to apply exact statistical methodologies in the context of large…

Computation · Statistics 2014-12-24 Umberto Picchini , Julie Lyng Forman

Charge Coupled Devices (CCDs) have been successfully used in several high energy physics experiments over the past two decades. Their high spatial resolution and thin sensitive layers make them an excellent tool for studying short-lived…

A composite quadric model (CQM) is an object modeled by piecewise linear or quadric patches. We study the continuous detection problem of a special type of CQM objects which are commonly used in CAD/CAM, that is, the boundary surfaces of…

Graphics · Computer Science 2013-12-02 Yi-King Choi , Wenping Wang , Bernard Mourrain , Changhe Tu , Xiaohong Jia , Feng Sun

Intrusion Detection Systems (IDSs) have played a significant role in the detection and prevention of cyber-attacks in traditional computing systems. It is not surprising that this technology is now being applied to secure Internet of Things…

Networking and Internet Architecture · Computer Science 2024-07-23 Mohammed Jouhari , Hafsa Benaddi , Khalil Ibrahimi

Molecular Dynamics (MD) simulations are essential for understanding the atomic-level behavior of molecular systems, giving insights into their transitions and interactions. However, classical MD techniques are limited by the trade-off…

Biomolecules · Quantitative Biology 2026-04-21 Ziyang Yu , Wenbing Huang , Yang Liu

Prediction of critical temperature $(T_c)$ of a superconductor remains a significant challenge in condensed matter physics. While the BCS theory explains superconductivity in conventional superconductors, there is no framework to predict…

Superconductivity · Physics 2026-01-08 Suhas Adiga , Umesh V. Waghmare

Industrial Control Networks (ICN) such as Supervisory Control and Data Acquisition (SCADA) systems are widely used in industries for monitoring and controlling physical processes. These industries include power generation and supply, gas…

Cryptography and Security · Computer Science 2019-11-14 Basem AL-Madani , Ahmad Shawahna , Mohammad Qureshi

Handling varying computational resources is a critical issue in modern AI applications. Adaptive deep networks, featuring the dynamic employment of multiple classifier heads among different layers, have been proposed to address…

Computer Vision and Pattern Recognition · Computer Science 2024-08-30 Xu Zhang , Zhipeng Xie , Haiyang Yu , Qitong Wang , Peng Wang , Wei Wang