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Investigation of age-related genes is of great importance for multiple purposes, for instance, improving our understanding of the mechanism of ageing, increasing life expectancy, age prediction, and other healthcare applications. In his…

Genomics · Quantitative Biology 2021-11-05 Salman Mohamadi , Donald Adjeroh

Aging clocks aim to estimate biological age, a measure of physiological state distinct from chronological age, from observable biomarkers, and are widely used for health assessment and disease analysis. DNA methylation is a particularly…

Machine Learning · Computer Science 2026-05-11 Qing Qing , Xikun Zhang , Zhongyuan Zhang , Jiarui Liu , Xingtong Yu , Xiaotao Shen , Ziqi Xu , Qixin Zhang , Zhe Wang , Renqiang Luo

Age estimation is a technique for predicting human ages from digital facial images, which analyzes a person's face image and estimates his/her age based on the year measure. Nowadays, intelligent age estimation and age synthesis have become…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Milad Taleby Ahvanooey , Qianmu Li

In recent years, there are various methods of estimating Biological Age (BA) have been developed. Especially with the development of machine learning (ML), there are more and more types of BA predictions, and the accuracy has been greatly…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Zhaonian Zhang , Richard Jiang , Danny Crookes , Paul Chazot

Over the last years, huge resources of biological and medical data have become available for research. This data offers great chances for machine learning applications in health care, e.g. for precision medicine, but is also challenging to…

Quantitative Methods · Quantitative Biology 2016-12-21 Lisa Handl , Adrin Jalali , Michael Scherer , Nico Pfeifer

DNA methylation is a crucial epigenetic marker used in various clocks to predict epigenetic age. However, many existing clocks fail to account for crucial information about CpG sites and their interrelationships, such as co-methylation…

Quantitative Methods · Quantitative Biology 2024-08-05 Saleh Sakib Ahmed , Nahian Shabab , Md. Abul Hassan Samee , M. Sohel Rahman

Accurately predicting chronological age from DNA methylation patterns is crucial for advancing biological age estimation. However, this task is made challenging by Epigenetic Correlation Drift (ECD) and Heterogeneity Among CpGs (HAC), which…

Genomics · Quantitative Biology 2025-01-07 Zipeng Wu , Daniel Herring , Fabian Spill , James Andrews

Epigenetic aging clocks play a pivotal role in estimating an individual's biological age through the examination of DNA methylation patterns at numerous CpG (Cytosine-phosphate-Guanine) sites within their genome. However, making valid…

Machine Learning · Statistics 2026-01-21 Zhe Fei , Yi Li

Epigenetic clocks based on DNA methylation have emerged as powerful tools for estimating biological age, with broad applications in aging research, age-related disease studies, and longevity science. Despite advances across machine learning…

Artificial Intelligence · Computer Science 2026-05-12 Yao Li , Xikun Zhang , Xiaotao Shen , Sonika Tyagi , Xin Zheng , Jiaxing Huang , Feng Xia

This paper is a part of a student project in Machine Learning at the Norwegian University of Science and Technology. In this paper, a deep convolutional neural network with five convolutional layers and three fully-connected layers is…

Computer Vision and Pattern Recognition · Computer Science 2021-05-17 Adrian Kjærran , Christian Bakke Vennerød , Erling Stray Bugge

It has been recently shown that Generative Adversarial Networks (GANs) can produce synthetic images of exceptional visual fidelity. In this work, we propose the GAN-based method for automatic face aging. Contrary to previous works employing…

Computer Vision and Pattern Recognition · Computer Science 2017-05-31 Grigory Antipov , Moez Baccouche , Jean-Luc Dugelay

Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease. Here we sought to further…

Human aging is a process controlled by both genetics and environment. Many studies have been conducted to identify a subset of genes related to aging from the human genome. Biologists implicitly categorize age-related genes into genes that…

Genomics · Quantitative Biology 2023-11-17 Salman Mohamadi , Donald A. Adjeroh

We present a novel framework to generate images of different age while preserving identity information, which is known as face aging. Different from most recent popular face aging networks utilizing Generative Adversarial Networks(GANs)…

Computer Vision and Pattern Recognition · Computer Science 2019-09-12 Zipeng Wang , Zhaoxiang Liu , Jianfeng Huang , Shiguo Lian , Yimin Lin

This is a study on facial information analysis technology for estimating gender and age, and poses are estimated using a transformation relationship matrix between the camera coordinate system and the world coordinate system for estimating…

Computer Vision and Pattern Recognition · Computer Science 2021-11-18 Gilheum Park , Sua Jung

Face synthesis, including face aging, in particular, has been one of the major topics that witnessed a substantial improvement in image fidelity by using generative adversarial networks (GANs). Most existing face aging approaches divide the…

Computer Vision and Pattern Recognition · Computer Science 2021-05-04 Zeqi Li , Ruowei Jiang , Parham Aarabi

This work introduces a novel deep-learning approach for estimating age from a single facial image by refining an initial age estimate. The refinement leverages a reference face database of individuals with similar ages and appearances. We…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Ran Sandhaus , Yosi Keller

Among the different biomarkers of aging based on omics and clinical data, DNA methylation clocks stand apart providing unmatched accuracy in assessing the biological age of both humans and animal models of aging. Here, we discuss robustness…

Genomics · Quantitative Biology 2018-11-16 Dmitriy I. Podolskiy , Vadim N. Gladyshev

We present a new method of predicting the ages of galaxies using a machine learning (ML) algorithm with the goal of providing an alternative to traditional methods. We aim to match the ability of traditional models to predict the ages of…

Astrophysics of Galaxies · Physics 2024-06-14 Laura. J. Hunt , Kevin. A. Pimbblet , David. M. Benoit

When a neural network estimates someone's age from a photograph, does it process biometric data? The answer depends on whether identity-discriminative representations arise within the network during inference, a question that may seem…

Computers and Society · Computer Science 2026-05-19 Nikita Marshalkin
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