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We introduce an epidemic model with varying infectivity and general exposed and infectious periods, where the infectivity of each individual is a random function of the elapsed time since infection, those function being i.i.d. for the…

Probability · Mathematics 2021-06-01 Raphael Forien , Guodong Pang , Etienne Pardoux

What role do asymptomatically infected individuals play in the transmission dynamics? There are many diseases, such as norovirus and influenza, where some infected hosts show symptoms of the disease while others are asymptomatically…

Populations and Evolution · Quantitative Biology 2018-01-29 Ka Yin Leung , Pieter Trapman , Tom Britton

We analyse the infection-age-dependent SIR model from a numerical point of view. First, we present an algorithm for calculating the solution the infection-age-structured SIR model without demography of the background host. Second, we…

Populations and Evolution · Quantitative Biology 2020-06-29 Ralph Brinks , Annika Hoyer

When an infectious disease strikes a population, the number of newly reported cases is often the only available information that one can obtain during early stages of the outbreak. An important goal of early outbreak analysis is to obtain a…

Quantitative Methods · Quantitative Biology 2013-05-30 Bahman Davoudi , Babak Pourbohloul , Joel Miller , Rafael Meza , Lauren Ancel Meyers , David J. D. Earn

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

Quantitative Methods · Quantitative Biology 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

Many infectious diseases can lead to re-infection. We examined the relationship between the prevalence of repeat infection and the basic reproductive number (R0). First we solved a generic, deterministic compartmental model of re-infection…

Populations and Evolution · Quantitative Biology 2019-03-15 Joshua Feldman , Sharmistha Mishra

In order to understand the cost of a potentially high infectiousness of symptomatic individuals or, on the contrary, the benefit of social distancing, quarantine, etc. in the course of an infectious disease, this paper considers a natural…

Probability · Mathematics 2024-04-29 Lamia Belhadji , Nicolas Lanchier , Max Mercer

Waning immunity and reinfection are critical features of many infectious diseases, but epidemiological models often fail to capture the intricate interaction between an individual's history of immunity and their current infection status;…

Populations and Evolution · Quantitative Biology 2026-03-25 Raimund M. Kovacevic , Nikolaos I. Stilianakis , Vladimir M. Veliov

A key parameter in models for the spread of infectious diseases is the basic reproduction number $R_0$, which is the expected number of secondary cases a typical infected primary case infects during its infectious period in a large mostly…

Populations and Evolution · Quantitative Biology 2017-09-05 Kristoffer Spricer , Pieter Trapman

We study the spread of susceptible-infected-recovered (SIR) infectious diseases where an individual's infectiousness and probability of recovery depend on his/her "age" of infection. We focus first on early outbreak stages when stochastic…

Populations and Evolution · Quantitative Biology 2009-05-14 Joel Miller , Bahman Davoudi , Rafael Meza , Anja Slim , Babak Pourbohloul

We study an individual-based stochastic epidemic model in which infected individuals become susceptible again following each infection. In contrast to classical compartment models, after each infection, the infectivity is a random function…

Probability · Mathematics 2025-04-29 Raphaël Forien , Guodong Pang , Étienne Pardoux , Arsene Brice Zotsa-Ngoufack

In this paper we first introduce the general stochastic epidemic model for the spread of infectious diseases. Then we give methods for inferring model parameters such as the basic reproduction number $R_0$ and vaccination coverage $v_c$…

Methodology · Statistics 2014-11-14 Tom Britton , Federica Giardina

A simple, but ``classical``, stochastic model for epidemic spread in a finite, but large, population is studied. The progress of the epidemic can be divided into three different phases that requires different tools to analyse. Initially the…

Populations and Evolution · Quantitative Biology 2018-05-29 Åke Svensson

Studies about epidemic modelling have been conducted since before 19th century. Both deterministic and stochastiic model were used to capture the dynamic of infection in the population. The purpose of this project is to investigate the…

Populations and Evolution · Quantitative Biology 2018-03-06 Kurnia Susvitasari

We study the Susceptible-Infected-Susceptible model of the spread of an endemic infection. We calculate an exact expression for the mean number of transmissions for all values of the population and the infectivity. We derive the large-N…

Populations and Evolution · Quantitative Biology 2007-09-20 David A. Kessler

A social (sexual) network is modeled by an extension of the configuration model to the situation where edges have weights, e.g. reflecting the number of sex-contacts between the individuals. An epidemic model is defined on the network such…

Probability · Mathematics 2011-12-21 Tom Britton , David Lindenstrand

In this paper, we consider a compartmental SIRS epidemic model with asymptomatic infection and seasonal succession, which is a periodic discontinuous differential system. The basic reproduction number $\mathcal{R}_0$ is defined and valuated…

Dynamical Systems · Mathematics 2017-08-15 Yilei Tang , Dongmei Xiao , Weinian Zhang , Di Zhu

We study contact epidemic models for the spread of infective diseases in finite populations. The size dependence enters in the infection rate. The dynamics of such models is then analyzed within the deterministic approximation, as well as…

Populations and Evolution · Quantitative Biology 2020-04-07 Ph. Blanchard , S. Nicolis

In the Staged Progression (SP) epidemic models, infected individuals are classified into a suitable number of states. The goal of these models is to describe as closely as possible the effect of differences in infectiousness exhibited by…

Dynamical Systems · Mathematics 2024-02-08 Luis Sanz-Lorenzo , Rafael Bravo de la Parra

Epidemiological data on seasonal influenza show that the growth rate of the number of infected individuals can increase passing from one exponential growth rate to another one with a larger exponent. Such behavior is not described by…

Populations and Evolution · Quantitative Biology 2020-04-01 Malay Banerjee , Alexey Tokarev , Vitaly Volpert
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