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As machine learning is applied to an increasing variety of complex problems, which are defined by high dimensional and complex data sets, the necessity for task oriented feature learning grows in importance. With the advancement of Deep…

Machine Learning · Computer Science 2016-07-06 Vishwajeet Singh , Killamsetti Ravi Kumar , K Eswaran

With a goal of accelerating fabrication of additively manufactured components with precise microstructures, we developed a method for structural characterization of key features in additively manufactured materials and parts. The method…

Computer Vision and Pattern Recognition · Computer Science 2023-02-14 Amra Peles , Vincent C. Paquit , Ryan R. Dehoff

Breast density classification is an essential part of breast cancer screening. Although a lot of prior work considered this problem as a task for learning algorithms, to our knowledge, all of them used small and not clinically realistic…

Computer Vision and Pattern Recognition · Computer Science 2017-11-13 Nan Wu , Krzysztof J. Geras , Yiqiu Shen , Jingyi Su , S. Gene Kim , Eric Kim , Stacey Wolfson , Linda Moy , Kyunghyun Cho

DNA-binding proteins are a class of proteins which have a specific or general affinity to DNA and include three important components: transcription factors; nucleases, and histones. DNA-binding proteins also perform important roles in many…

Computer Vision and Pattern Recognition · Computer Science 2012-07-12 Sokyna Qatawneh , Afaf Alneaimi , Thamer Rawashdeh , Mmohammad Muhairat , Rami Qahwaji , Stan Ipson

We propose introspective convolutional networks (ICN) that emphasize the importance of having convolutional neural networks empowered with generative capabilities. We employ a reclassification-by-synthesis algorithm to perform training…

Computer Vision and Pattern Recognition · Computer Science 2018-01-08 Long Jin , Justin Lazarow , Zhuowen Tu

The gesture recognition using motion capture data and depth sensors has recently drawn more attention in vision recognition. Currently most systems only classify dataset with a couple of dozens different actions. Moreover, feature…

Computer Vision and Pattern Recognition · Computer Science 2014-09-02 Kyunghyun Cho , Xi Chen

We have developed a methodology for the systematic generation of a large image dataset of macerated wood references, which we used to generate image data for nine hardwood genera. This is the basis for a substantial approach to automate,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-26 Lars Nieradzik , Jördis Sieburg-Rockel , Stephanie Helmling , Janis Keuper , Thomas Weibel , Andrea Olbrich , Henrike Stephani

In post genomic era with the advent of new technologies a huge amount of complex molecular data are generated with high throughput. The management of this biological data is definitely a challenging task due to complexity and heterogeneity…

Databases · Computer Science 2014-03-13 Ananya Bose , Suprativ Saha

Convolutional neural networks (CNNs) have been demonstrated their powerful ability to extract discriminative features for hyperspectral image classification. However, general deep learning methods for CNNs ignore the influence of complex…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Zhiqiang Gong , Xian Zhou , Wen Yao

Breast cancer is one of the leading fatal disease worldwide with high risk control if early discovered. Conventional method for breast screening is x-ray mammography, which is known to be challenging for early detection of cancer lesions.…

Computer Vision and Pattern Recognition · Computer Science 2020-03-11 Essam A. Rashed , M. Samir Abou El Seoud

De novo peptide sequencing from mass spectrometry data is an important method for protein identification. Recently, various deep learning approaches were applied for de novo peptide sequencing and DeepNovoV2 is one of the represetative…

Quantitative Methods · Quantitative Biology 2022-03-18 Cheng Ge , Yi Lu , Jia Qu , Liangxu Xie , Feng Wang , Hong Zhang , Ren Kong , Shan Chang

Kernel classifiers and regressors designed for structured data, such as sequences, trees and graphs, have significantly advanced a number of interdisciplinary areas such as computational biology and drug design. Typically, kernels are…

Machine Learning · Computer Science 2020-01-14 Hanjun Dai , Bo Dai , Le Song

Automated identification of protein conformational states from simulation of an ensemble of structures is a hard problem because it requires teaching a computer to recognize shapes. We adapt the naive Bayes classifier from the machine…

Computational Physics · Physics 2020-12-02 David M. Rogers

Deep learning is a subset of a broader family of machine learning methods based on learning data representations. These models are inspired by human biological nervous systems, even if there are various differences pertaining to the…

Neural and Evolutionary Computing · Computer Science 2019-05-22 Adriano Baldeschi , Raffaella Margutti , Adam Miller

Research in bioinformatics is a complex phenomenon as it overlaps two knowledge domains, namely, biological and computer sciences. This paper has tried to introduce an efficient data mining approach for classifying proteins into some useful…

Computational Engineering, Finance, and Science · Computer Science 2011-11-11 Muhammad Mahbubur Rahman , Arif Ul Alam , Abdullah-Al-Mamun , Tamnun E Mursalin

Protein contacts provide key information for the understanding of protein structure and function, and therefore contact prediction from sequences is an important problem. Recent research shows that some correctly predicted long-range…

Quantitative Methods · Quantitative Biology 2020-09-02 Siqi Sun

Proteins play a pivotal role in biological systems. The use of machine learning algorithms for protein classification can assist and even guide biological experiments, offering crucial insights for biotechnological applications. We…

Quantitative Methods · Quantitative Biology 2024-10-24 Yizheng Wang , Yixiao Zhai , Yijie Ding , Quan Zou

Deep learning has transformed protein design, enabling accurate structure prediction, sequence optimization, and de novo protein generation. Advances in single-chain protein structure prediction via AlphaFold2, RoseTTAFold, ESMFold, and…

Machine Learning · Computer Science 2025-02-27 Gregory W. Kyro , Tianyin Qiu , Victor S. Batista

The knowledge regarding the function of proteins is necessary as it gives a clear picture of biological processes. Nevertheless, there are many protein sequences found and added to the databases but lacks functional annotation. The…

Quantitative Methods · Quantitative Biology 2018-09-13 Anu Vazhayil , Vinayakumar R , Soman KP

The Deep Convolutional Neural Network (DCNN) is one of the most powerful and successful deep learning approaches. DCNNs have already provided superior performance in different modalities of medical imaging including breast cancer…

Computer Vision and Pattern Recognition · Computer Science 2018-11-13 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari
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