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Extracting and detecting spike activities from the fluorescence observations is an important step in understanding how neuron systems work. The main challenge lies in that the combination of the ambient noise with dynamic baseline…

Neurons and Cognition · Quantitative Biology 2019-02-01 Zhuangkun Wei , Bin Li , Weisi Guo , Wenxiu Hu , Chenglin Zhao

Multilevel models (MLMs) are a central building block of the Bayesian workflow. They enable joint, interpretable modeling of data across hierarchical levels and provide a fully probabilistic quantification of uncertainty. Despite their…

Bayesian models provide a framework for probabilistic modelling of complex datasets. However, many of such models are computationally demanding especially in the presence of large datasets. On the other hand, in sensor network applications,…

Machine Learning · Computer Science 2015-07-06 Behnam Babagholami-Mohamadabadi , Sejong Yoon , Vladimir Pavlovic

This paper considers a novel problem, bi-level graphical modeling, in which multiple individual graphical models can be considered as variants of a common group-level graphical model and inference of both the group- and individual-level…

Methodology · Statistics 2021-08-12 Lin Zhang , Andrew DiLernia , Karina Quevedo , Jazmin Camchong , Kelvin Lim , Wei Pan1

Task-based fMRI provides a direct readout of task-evoked neural dynamics, but it is expensive and difficult to acquire at scale, motivating rest-to-task synthesis from widely available resting-state fMRI (rsfMRI). We propose FM-fMRI, an…

Machine Learning · Computer Science 2026-05-27 Peiyu Duan , Jiyao Wang , Nicha C. Dvornek , Junlin Yang , Ziqi Gao , Lawrence H. Staib , James S. Duncan

Decoding visual-semantic information from brain signals, such as functional MRI (fMRI), across different subjects poses significant challenges, including low signal-to-noise ratio, limited data availability, and cross-subject variability.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Ruizhe Zheng , Lichao Sun

In group activity recognition, the temporal dynamics of the whole activity can be inferred based on the dynamics of the individual people representing the activity. We build a deep model to capture these dynamics based on LSTM (long-short…

Computer Vision and Pattern Recognition · Computer Science 2016-04-07 Moustafa Ibrahim , Srikanth Muralidharan , Zhiwei Deng , Arash Vahdat , Greg Mori

Standard detection of evoked brain activity in functional MRI (fMRI) relies on a fixed and known shape of the impulse response of the neurovascular coupling, namely the hemodynamic response function (HRF). To cope with this issue, the joint…

Applications · Statistics 2015-01-07 Aina Frau-Pascual , Thomas Vincent , Florence Forbes , Philippe Ciuciu

Segmentation of structural and diffusion MRI (sMRI/dMRI) is usually performed independently in neuroimaging pipelines. However, some brain structures (e.g., globus pallidus, thalamus and its nuclei) can be extracted more accurately by…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Juan Eugenio Iglesias , Koen Van Leemput , Polina Golland , Anastasia Yendiki

Functional magnetic resonance imaging (fMRI) data provides information concerning activity in the brain and in particular the interactions between brain regions. Resting state fMRI data is widely used for inferring connectivities in the…

Applications · Statistics 2019-03-04 Christina Stoehr , John A D Aston , Claudia Kirch

One approach, for understanding human brain functioning, is to analyze the changes in the brain while performing cognitive tasks. Towards this, Functional Magnetic Resonance (fMR) images of subjects performing well-defined tasks are widely…

Computer Vision and Pattern Recognition · Computer Science 2016-04-20 Hariharan Ramasangu , Neelam Sinha

Large-scale electrophysiological recordings now allow simultaneous monitoring of thousands of neurons across multiple brain regions, revealing structured variability in neural population activity. Understanding how these collective patterns…

Neurons and Cognition · Quantitative Biology 2026-03-12 Nicolas Béreux , Giovanni Catania , Aurélien Decelle , Francesca Mignacco , Alfonso de Jesús Navas Gómez , Beatriz Seoane

Neural activity data can be associated with behavioral and physiological variables by analyzing their changes in the temporal domain. However, such relationships are often difficult to quantify and test, requiring advanced computational…

Neurons and Cognition · Quantitative Biology 2026-01-23 Nick Yao Larsen , Laura Paulsen , Christine Ahrends , Anderson M. Winkler , Diego Vidaurre

Accurate fMRI analysis requires sensitivity to temporal structure across multiple scales, as BOLD signals encode cognitive processes that emerge from fast transient dynamics to slower, large-scale fluctuations. Existing deep learning (DL)…

Signal Processing · Electrical Eng. & Systems 2026-01-06 Furkan Genç , Boran İsmet Macun , Sait Sarper Özaslan , Emine U. Saritas , Tolga Çukur

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

Machine Learning · Computer Science 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

Advances in neural recording present increasing opportunities to study neural activity in unprecedented detail. Latent variable models (LVMs) are promising tools for analyzing this rich activity across diverse neural systems and behaviors,…

This paper describes an approach of using dynamic Structural Equation Modeling (SEM) analysis to estimate the connectivity networks from resting-state fMRI data measured by a multiband EPI sequence. Two structural equation models were…

Neurons and Cognition · Quantitative Biology 2017-04-03 Jiancheng Zhuang

Multivariate analysis of fMRI data has benefited substantially from advances in machine learning. Most recently, a range of probabilistic latent variable models applied to fMRI data have been successful in a variety of tasks, including…

Motivation: NMR spectra are widely used in metabolomics to obtain metabolite profiles in complex biological mixtures. Common methods used to assign and estimate concentrations of metabolites involve either an expert manual peak fitting or…

Applications · Statistics 2012-05-30 Jie Hao , William Astle , Maria De Iorio , Timothy Ebbels

Decoding human brain activities via functional magnetic resonance imaging (fMRI) has gained increasing attention in recent years. While encouraging results have been reported in brain states classification tasks, reconstructing the details…

Artificial Intelligence · Computer Science 2017-07-12 Changde Du , Changying Du , Huiguang He