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Throughout the life sciences we routinely seek to interpret measurements and observations using parameterised mechanistic mathematical models. A fundamental and often overlooked choice in this approach involves relating the solution of a…

Quantitative Methods · Quantitative Biology 2023-11-10 Ryan J. Murphy , Oliver J. Maclaren , Matthew J. Simpson

Generative models frequently suffer miscalibration, wherein statistics of the sampling distribution, such as the fraction of generations in a given class, deviate from desired values. We frame calibration as a constrained optimization…

Machine Learning · Statistics 2026-05-29 Henry D. Smith , Nathaniel L. Diamant , Brian L. Trippe

In this work, we quantitatively calibrate the performance of global and local models in federated learning through a multi-criterion optimization-based framework, which we cast as a constrained program. The objective of a device is its…

Machine Learning · Computer Science 2023-02-02 Amrit Singh Bedi , Chen Fan , Alec Koppel , Anit Kumar Sahu , Brian M. Sadler , Furong Huang , Dinesh Manocha

Despite recent advances, the remaining bottlenecks in deep generative models are necessity of extensive training and difficulties with generalization from small number of training examples. We develop a new generative model called…

Machine Learning · Statistics 2017-09-06 Sergey Bartunov , Dmitry P. Vetrov

Machine learning models suffer from overfitting, which is caused by a lack of labeled data. To tackle this problem, we proposed a framework of regularization methods, called density-fixing, that can be used commonly for supervised and…

Machine Learning · Computer Science 2020-09-08 Masanari Kimura , Ryohei Izawa

We study the problem of learning latent variables in Gaussian graphical models. Existing methods for this problem assume that the precision matrix of the observed variables is the superposition of a sparse and a low-rank component. In this…

Machine Learning · Statistics 2017-07-12 Mohammadreza Soltani , Chinmay Hegde

There are many uses for linear fitting; the context here is interpolation and denoising of data, as when you have calibration data and you want to fit a smooth, flexible function to those data. Or you want to fit a flexible function to…

Data Analysis, Statistics and Probability · Physics 2021-09-22 David W. Hogg , Soledad Villar

In this study, we propose a general model capable of addressing heterogeneity in higher-order moments while preserving mean and variance, including the t, Laplace, and skew-normal distributions as special cases. Our model flexibly…

Methodology · Statistics 2025-03-18 Hajime Kuno , Daisuke Murakami

Gaussian processes (GPs) are widely used as surrogate models for complicated functions in scientific and engineering applications. In many cases, prior knowledge about the function to be approximated, such as monotonicity, is available and…

Machine Learning · Statistics 2025-07-10 Chao Zhang , Jasper M. Everink , Jakob Sauer Jørgensen

Estimating the dependences between random variables, and ranking them accordingly, is a prevalent problem in machine learning. Pursuing frequentist and information-theoretic approaches, we first show that the p-value and the mutual…

Machine Learning · Computer Science 2012-07-02 Harald Steck

Existing methods to measure sentence similarity are faced with two challenges: (1) labeled datasets are usually limited in size, making them insufficient to train supervised neural models; (2) there is a training-test gap for unsupervised…

Computation and Language · Computer Science 2022-02-01 Xiaofei Sun , Yuxian Meng , Xiang Ao , Fei Wu , Tianwei Zhang , Jiwei Li , Chun Fan

Over-parameterized neural network models often lead to significant performance discrepancies between training and test sets, a phenomenon known as overfitting. To address this, researchers have proposed numerous regularization techniques…

Machine Learning · Computer Science 2025-01-27 RuiZhe Jiang , Haotian Lei

In this work, the distributional properties of the goodness-of-fit term in likelihood-based information criteria are explored. These properties are then leveraged to construct a novel goodness-of-fit test for normal linear regression models…

Methodology · Statistics 2023-09-20 Scott H. Koeneman , Joseph E. Cavanaugh

While many methods are available to detect structural changes in a time series, few procedures are available to quantify the uncertainty of these estimates post-detection. In this work, we fill this gap by proposing a new framework to test…

Methodology · Statistics 2021-04-16 Sean Jewell , Paul Fearnhead , Daniela Witten

The generalization performance of a risk prediction model can be evaluated by its calibration, which measures the agreement between predicted and observed outcomes on external validation data. Here, methods for assessing the calibration of…

Methodology · Statistics 2020-01-31 Moritz Berger , Matthias Schmid

In general, synthesis models provide the mean value of the distribution of possible integrated luminosities, this distribution (and not only its mean value) being the actual description of the integrated luminosity. Therefore, to obtain the…

Astrophysics · Physics 2019-06-19 M. Cervino , V. Luridiana

Generalization is the ability of a model to predict on unseen domains and is a fundamental task in machine learning. Several generalization bounds, both theoretical and empirical have been proposed but they do not provide tight bounds .In…

Machine Learning · Computer Science 2021-01-19 Sumukh Aithal K , Dhruva Kashyap , Natarajan Subramanyam

The modeling of probability distributions, specifically generative modeling and density estimation, has become an immensely popular subject in recent years by virtue of its outstanding performance on sophisticated data such as images and…

Machine Learning · Statistics 2023-01-02 Hongkang Yang

This article introduces a novel nonparametric methodology for Generalized Linear Models which combines the strengths of the binary regression and latent variable formulations for categorical data, while overcoming their disadvantages.…

Machine Learning · Statistics 2021-10-12 K. P. Chowdhury

Inference of physical parameters from reference data is a well studied problem with many intricacies (inconsistent sets of data due to experimental systematic errors, approximate physical models...). The complexity is further increased when…

Data Analysis, Statistics and Probability · Physics 2017-09-06 Pascal Pernot , Fabien Cailliez