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Deep neural networks for survival prediction outper-form classical approaches in discrimination, which is the ordering of patients according to their time-of-event. Conversely, classical approaches like the Cox Proportional Hazards model…

Machine Learning · Computer Science 2022-09-01 Patrick Fuhlert , Anne Ernst , Esther Dietrich , Fabian Westhaeusser , Karin Kloiber , Stefan Bonn

Overlap-based metrics such as the Dice Similarity Coefficient (DSC) penalize segmentation errors more heavily in smaller structures. As organ size differs by sex, this implies that a segmentation error of equal magnitude may result in lower…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Hartmut Häntze , Myrthe Buser , Alessa Hering , Lisa C. Adams , Keno K. Bressem

The soft Dice loss (SDL) has taken a pivotal role in numerous automated segmentation pipelines in the medical imaging community. Over the last years, some reasons behind its superior functioning have been uncovered and further optimizations…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Zifu Wang , Teodora Popordanoska , Jeroen Bertels , Robin Lemmens , Matthew B. Blaschko

Deep neural networks (DNNs) have achieved significant success across various tasks, but ensuring reliable uncertainty estimates, known as model calibration, is crucial for their safe and effective deployment. Modern DNNs often suffer from…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Linwei Tao , Minjing Dong , Chang Xu

Deep convolutional neural networks (CNN) have proven to be remarkably effective in semantic segmentation tasks. Most popular loss functions were introduced targeting improved volumetric scores, such as the Dice coefficient (DSC). By design,…

Objective: Overlapping measures are often utilized to quantify the similarity between two binary regions. However, modern segmentation algorithms output a probability or confidence map with continuous values in the zero-to-one interval.…

Computer Vision and Pattern Recognition · Computer Science 2019-06-27 Reuben R Shamir , Yuval Duchin , Jinyoung Kim , Guillermo Sapiro , Noam Harel

In the field of medical image analysis, achieving high accuracy is not enough; ensuring well-calibrated predictions is also crucial. Confidence scores of a deep neural network play a pivotal role in explainability by providing insights into…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Abhishek Singh Sambyal , Usma Niyaz , Narayanan C. Krishnan , Deepti R. Bathula

Estimated uncertainty by approximate posteriors in Bayesian neural networks are prone to miscalibration, which leads to overconfident predictions in critical tasks that have a clear asymmetric cost or significant losses. Here, we extend the…

Machine Learning · Computer Science 2022-06-17 Biraja Ghoshal , Allan Tucker

We propose the Signal Dice Similarity Coefficient (SDSC), a structure-aware metric function for time series self-supervised representation learning. Most Self-Supervised Learning (SSL) methods for signals commonly adopt distance-based…

Machine Learning · Computer Science 2026-01-30 Jeyoung Lee , Hochul Kang

Deep Neural Networks ( DNN s) are known to make overconfident mistakes, which makes their use problematic in safety-critical applications. State-of-the-art ( SOTA ) calibration techniques improve on the confidence of predicted labels alone…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Ramya Hebbalaguppe , Jatin Prakash , Neelabh Madan , Chetan Arora

Medical image segmentation has played an important role in medical analysis and widely developed for many clinical applications. Deep learning-based approaches have achieved high performance in semantic segmentation but they are limited to…

Image and Video Processing · Electrical Eng. & Systems 2020-12-07 Ngan Le , Trung Le , Kashu Yamazaki , Toan Duc Bui , Khoa Luu , Marios Savides

Proper confidence calibration of deep neural networks is essential for reliable predictions in safety-critical tasks. Miscalibration can lead to model over-confidence and/or under-confidence; i.e., the model's confidence in its prediction…

Machine Learning · Computer Science 2023-08-08 Shuang Ao , Stefan Rueger , Advaith Siddharthan

In critical decision support systems based on medical imaging, the reliability of AI-assisted decision-making is as relevant as predictive accuracy. Although deep learning models have demonstrated significant accuracy, they frequently…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Hua Xu , Julián D. Arias-Londoño , Juan I. Godino-Llorente

Uncertainty is a fundamental aspect of real-world scenarios, where perfect information is rarely available. Humans naturally develop complex internal models to navigate incomplete data and effectively respond to unforeseen or partially…

Machine Learning · Computer Science 2025-08-08 Wenhao Liang , Chang Dong , Liangwei Zheng , Wei Zhang , Weitong Chen

Deep learning has achieved the state-of-the-art performance across medical imaging tasks; however, model calibration is often not considered. Uncalibrated models are potentially dangerous in high-risk applications since the user does not…

Computer Vision and Pattern Recognition · Computer Science 2023-02-13 Skylar E. Stolte , Kyle Volle , Aprinda Indahlastari , Alejandro Albizu , Adam J. Woods , Kevin Brink , Matthew Hale , Ruogu Fang

Neural network-based decisions tend to be overconfident, where their raw outcome probabilities do not align with the true decision probabilities. Calibration of neural networks is an essential step towards more reliable deep learning…

Machine Learning · Computer Science 2025-02-19 Geetanjali Bihani , Julia Taylor Rayz

Manual segmentation is used as the gold-standard for evaluating neural networks on automated image segmentation tasks. Due to considerable heterogeneity in shapes, colours and textures, demarcating object boundaries is particularly…

Image and Video Processing · Electrical Eng. & Systems 2021-11-02 Michael Yeung , Guang Yang , Evis Sala , Carola-Bibiane Schönlieb , Leonardo Rundo

Lung cancer is one of the significant causes of cancer-related deaths globally. Early detection and treatment improve the chances of survival. Traditionally CT scans have been used to extract the most significant lung infection information…

Image and Video Processing · Electrical Eng. & Systems 2024-01-23 Mehar Prateek Kalra , Mansi Singhal , Rohan Raju Dhanakashirur

The Dice score is widely used for binary segmentation due to its robustness to class imbalance. Soft generalisations of the Dice score allow it to be used as a loss function for training convolutional neural networks (CNN). Although CNNs…

Computer Vision and Pattern Recognition · Computer Science 2018-02-27 Lucas Fidon , Wenqi Li , Luis C. Garcia-Peraza-Herrera , Jinendra Ekanayake , Neil Kitchen , Sebastien Ourselin , Tom Vercauteren

Within medical imaging segmentation, the Dice coefficient and Hausdorff-based metrics are standard measures of success for deep learning models. However, modern loss functions for medical image segmentation often only consider the Dice…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Adrian Celaya , Beatrice Riviere , David Fuentes