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This study investigates the spatial integration of agent-based models (ABMs) and compartmental models for infectious disease modeling, presenting a novel hybrid approach and examining its implications. ABMs offer detailed insights by…

Populations and Evolution · Quantitative Biology 2025-02-06 Inan Bostanci , Tim Conrad

This study offers a new paradigm of individual-level modeling to address the grand challenge of incorporating human behavior in epidemic models. Using generative artificial intelligence in an agent-based epidemic model, each agent is…

Artificial Intelligence · Computer Science 2023-07-12 Ross Williams , Niyousha Hosseinichimeh , Aritra Majumdar , Navid Ghaffarzadegan

Understanding pedestrian dynamics is critical for mitigating crowd-related risks and improving public safety. In this work, we propose a data-driven mesoscopic modeling framework that combines the kinetic theory of active particles with…

Physics and Society · Physics 2026-05-29 Santiago Rosa , Manuel Pulido , Orlando Billoni , Juan Martín Guerrieri , Juan Pablo Agnelli

Agent-based models of disease transmission involve stochastic rules that specify how a number of individuals would infect one another, recover or be removed from the population. Common yet stringent assumptions stipulate interchangeability…

Computation · Statistics 2021-01-29 Nianqiao Ju , Jeremy Heng , Pierre E. Jacob

Simulation with agent-based models is increasingly used in the study of complex socio-technical systems and in social simulation in general. This paradigm offers a number of attractive features, namely the possibility of modeling emergent…

Physics and Society · Physics 2015-10-27 Giovanni Luca Ciampaglia

Understanding dynamics of an outbreak like that of COVID-19 is important in designing effective control measures. This study aims to develop an agent based model that compares changes in infection progression by manipulating different…

Populations and Evolution · Quantitative Biology 2021-06-24 Anik Burman , Sayak Chatterjee , Pramit Ghosh , Indranil Mukhokadhyay

Modelling epidemics using contact networks provides a significant improvement over classical compartmental models by explicitly incorporating the network of contacts. However, while network-based models describe disease spread on a given…

Physics and Society · Physics 2025-02-18 Andrés Guzmán , Federico Malizia , Gyeong Ho Park , Boseung Choi , Diana Cole , István Z. Kiss

Mathematical and simulation models are often used to predict the spread of a disease and estimate the impact of public health interventions, and many such models have been developed and used during the COVID-19 pandemic. This paper…

Populations and Evolution · Quantitative Biology 2024-03-18 Jeffrey W. Herrmann , Hongjie Liu , Donald K. Milton

Modern Bayesian approaches and workflows emphasize in how simulation is important in the context of model developing. Simulation can help researchers understand how the model behaves in a controlled setting and can be used to stress the…

Epidemiological simulations as a method are used to better understand and predict the spreading of infectious diseases, for example of COVID-19. This paper presents an approach that combines person-centric data-driven human mobility…

Data assimilation is the task to combine evolution models and observational data in order to produce reliable predictions. In this paper, we focus on ensemble-based recursive data assimilation problems. Our main contribution is a hybrid…

Numerical Analysis · Mathematics 2016-02-26 Nawinda Chustagulprom , Sebastian Reich , Maria Reinhardt

When modeling the dynamics of infectious disease, the incorporation of contact network information allows for the capture of the non-randomness and heterogeneity of realistic contact patterns. Oftentimes, it is assumed that the underlying…

Populations and Evolution · Quantitative Biology 2024-04-17 Maxwell H. Wang , Jukka-Pekka Onnela

Agent-based models (ABMs) have emerged as distinguished tools for epidemic modeling due to their ability to capture detailed human contact patterns and can, thus, support decision-makers in times of outbreaks and epidemics. However, as a…

Physics and Society · Physics 2026-02-04 Sascha Korf , Sophia Johanna Wagner , Gerta Köster , Martin J. Kühn

Computational models of infectious disease can be broadly categorized into two types: individual-based (Agent-based), or compartmental models. While compartmental models can be structured to separate distinct sectors of a population, they…

Populations and Evolution · Quantitative Biology 2021-12-14 Cameron Zachreson , Sheryl Chang , Nathan Harding , Mikhail Prokopenko

Disease spread in most biological populations requires the proximity of agents. In populations where the individuals have spatial mobility, the contact graph is generated by the "collision dynamics" of the agents, and thus the evolution of…

Physics and Society · Physics 2007-06-07 Z. Toroczkai , H. Guclu

The Ensemble Kalman Filter (EnKF) is a popular sequential data assimilation method that has been increasingly used for parameter estimation and forecast prediction in epidemiological studies. The observation function plays a critical role…

Methodology · Statistics 2021-07-20 Leah Mitchell , Andrea Arnold

Interaction-driven modeling of diseases over real-world contact data has been shown to promote the understanding of the spread of diseases in communities. This temporal modeling follows the path-preserving order and timing of the contacts,…

Applications · Statistics 2023-07-13 Yanir Marmor , Alex Abbey , Yuval Shahar , Osnat Mokryn

We propose the novel use of a generative adversarial network (GAN) (i) to make predictions in time (PredGAN) and (ii) to assimilate measurements (DA-PredGAN). In the latter case, we take advantage of the natural adjoint-like properties of…

Machine Learning · Computer Science 2023-01-26 Vinicius L. S. Silva , Claire E. Heaney , Yaqi Li , Christopher C. Pain

Data assimilation algorithms are used to estimate the states of a dynamical system using partial and noisy observations. The ensemble Kalman filter has become a popular data assimilation scheme due to its simplicity and robustness for a…

Numerical Analysis · Mathematics 2021-06-23 Gottfried Hastermann , Maria Reinhardt , Rupert Klein , Sebastian Reich

Human cognitive responses, behavioral responses, and disease dynamics co-evolve over the course of any disease outbreak, and can result in complex feedbacks. We present a dynamic agent-based model that explicitly couples the spread of…