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We introduce MediX-R1, an open-ended Reinforcement Learning (RL) framework for medical multimodal large language models (MLLMs) that enables clinically grounded, free-form answers beyond multiple-choice formats. MediX-R1 fine-tunes a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Sahal Shaji Mullappilly , Mohammed Irfan Kurpath , Omair Mohamed , Mohamed Zidan , Fahad Khan , Salman Khan , Rao Anwer , Hisham Cholakkal

Recent work has shown that deep reinforcement-learning agents can learn to follow language-like instructions from infrequent environment rewards. However, this places on environment designers the onus of designing language-conditional…

Artificial Intelligence · Computer Science 2019-12-24 Dzmitry Bahdanau , Felix Hill , Jan Leike , Edward Hughes , Arian Hosseini , Pushmeet Kohli , Edward Grefenstette

Reinforcement learning (RL) commonly relies on scalar rewards with limited ability to express temporal, conditional, or safety-critical goals, and can lead to reward hacking. Temporal logic expressible via the more general class of…

Artificial Intelligence · Computer Science 2025-11-26 Dominik Wagner , Leon Witzman , Luke Ong

We present EHRMIND, a practical recipe for adapting large language models (LLMs) to complex clinical reasoning tasks using reinforcement learning with verifiable rewards (RLVR). While RLVR has succeeded in mathematics and coding, its…

Computation and Language · Computer Science 2025-06-02 Jiacheng Lin , Zhenbang Wu , Jimeng Sun

Inverse reinforcement learning (IRL), which infers reward functions from demonstrations, is a valuable tool for modeling and understanding decision-making behavior. Many variants of IRL have been developed to capture complexities of human…

Machine Learning · Computer Science 2026-05-14 Leo Benac , Abhishek Sharma , Alihan Huyuk , Finale Doshi-Velez

The healthcare sector has experienced a rapid accumulation of digital data recently, especially in the form of electronic health records (EHRs). EHRs constitute a precious resource that IS researchers could utilize for clinical applications…

Machine Learning · Computer Science 2024-11-06 Thiti Suttaket , L Vivek Harsha Vardhan , Stanley Kok

Recent reinforcement learning (RL) approaches have advanced radiology report generation (RRG), yet two core limitations persist: (1) report-level rewards offer limited evidence-grounded guidance for clinical faithfulness; and (2) current…

Machine Learning · Computer Science 2026-04-16 Qin Zhou , Guoyan Liang , Qianyi Yang , Jingyuan Chen , Sai Wu , Chang Yao , Zhe Wang

Reinforcement learning (RL) algorithms usually require a substantial amount of interaction data and perform well only for specific tasks in a fixed environment. In some scenarios such as healthcare, however, usually only few records are…

Machine Learning · Computer Science 2020-12-17 Chaochao Lu , Biwei Huang , Ke Wang , José Miguel Hernández-Lobato , Kun Zhang , Bernhard Schölkopf

Standard regression techniques, while powerful, are often constrained by predefined, differentiable loss functions such as mean squared error. These functions may not fully capture the desired behavior of a system, especially when dealing…

Machine Learning · Computer Science 2025-08-04 Yongchao Huang

Leveraging multimodal large models for image segmentation has become a prominent research direction. However, existing approaches typically rely heavily on manually annotated datasets that include explicit reasoning processes, which are…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Jiaqi Huang , Zunnan Xu , Jun Zhou , Ting Liu , Yicheng Xiao , Mingwen Ou , Bowen Ji , Xiu Li , Kehong Yuan

The goal of precision medicine is to provide individualized treatment at each stage of chronic diseases, a concept formalized by Dynamic Treatment Regimes (DTR). These regimes adapt treatment strategies based on decision rules learned from…

Methodology · Statistics 2025-06-09 Sophia Yazzourh , Nicolas Savy , Philippe Saint-Pierre , Michael R. Kosorok

Reinforcement learning from verifiable rewards (RLVR) has recently gained attention for its ability to elicit self-evolved reasoning capabilitie from base language models without explicit reasoning supervisions, as demonstrated by…

Computation and Language · Computer Science 2025-02-28 Sheng Zhang , Qianchu Liu , Guanghui Qin , Tristan Naumann , Hoifung Poon

Reinforcement Learning (RL) has been shown to substantially improve the reasoning capability of small and large language models (LLMs), but existing approaches typically rely on verifiable rewards, hence ground truth labels. We propose an…

Computation and Language · Computer Science 2026-04-06 Yiyang Shen , Lifu Tu , Weiran Wang

In the era of Large Language Models (LLMs), alignment has emerged as a fundamental yet challenging problem in the pursuit of more reliable, controllable, and capable machine intelligence. The recent success of reasoning models and…

Machine Learning · Computer Science 2025-07-18 Hao Sun , Mihaela van der Schaar

Attention-based sequential recommendation methods have shown promise in accurately capturing users' evolving interests from their past interactions. Recent research has also explored the integration of reinforcement learning (RL) into these…

Machine Learning · Computer Science 2024-04-19 Melissa Mozifian , Tristan Sylvain , Dave Evans , Lili Meng

Reinforcement learning with verifiable rewards (RLVR) has emerged as a promising paradigm for post-training large language models (LLMs) on complex reasoning tasks. Yet, the conditions under which RLVR yields robust generalization remain…

Machine Learning · Computer Science 2026-03-05 Brian Lu , Hongyu Zhao , Shuo Sun , Hao Peng , Rui Ding , Hongyuan Mei

Reasoning in large language models has long been a central research focus, and recent studies employing reinforcement learning (RL) have introduced diverse methods that yield substantial performance gains with minimal or even no external…

Inverse Reinforcement Learning (IRL) aims to facilitate a learner's ability to imitate expert behavior by acquiring reward functions that explain the expert's decisions. Regularized IRL applies strongly convex regularizers to the learner's…

Machine Learning · Computer Science 2020-12-04 Wonseok Jeon , Chen-Yang Su , Paul Barde , Thang Doan , Derek Nowrouzezahrai , Joelle Pineau

Tabular data serves as the backbone of modern data analysis and scientific research. While Large Language Models (LLMs) fine-tuned via Supervised Fine-Tuning (SFT) have significantly improved natural language interaction with such…

There has been considerable interest in leveraging RL and stochastic control methods to learn optimal treatment strategies for critically ill patients, directly from observational data. However, there is significant ambiguity on the control…

Machine Learning · Computer Science 2022-07-21 Thesath Nanayakkara
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