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Motivated by applications in biological science, we propose a novel test to assess the conditional mean dependence of a response variable on a large number of covariates. Our procedure is built on the martingale difference divergence…

Statistics Theory · Mathematics 2017-01-31 Xianyang Zhang , Shun Yao , Xiaofeng Shao

Testing the dependency between two random variables is an important inference problem in statistics since many statistical procedures rely on the assumption that the two samples are independent. To test whether two samples are independent,…

Methodology · Statistics 2023-01-04 Jin-Ting Zhang , Tianming Zhu

We study properties of two resampling scenarios: Conditional Randomisation and Conditional Permutation schemes, which are relevant for testing conditional independence of discrete random variables $X$ and $Y$ given a random variable $Z$.…

Statistics Theory · Mathematics 2023-04-14 Małgorzata Łazęcka , Bartosz Kołodziejek , Jan Mielniczuk

Testing the equality of two conditional distributions is crucial in various modern applications, including transfer learning and causal inference. Despite its importance, this fundamental problem has received surprisingly little attention…

Methodology · Statistics 2025-09-04 Jian Yan , Zhuoxi Li , Xianyang Zhang

Dependence measures based on reproducing kernel Hilbert spaces, also known as Hilbert-Schmidt Independence Criterion and denoted HSIC, are widely used to statistically decide whether or not two random vectors are dependent. Recently,…

Statistics Theory · Mathematics 2021-01-13 Mélisande Albert , Béatrice Laurent , Amandine Marrel , Anouar Meynaoui

We study the problems of sequential nonparametric two-sample and independence testing. Sequential tests process data online and allow using observed data to decide whether to stop and reject the null hypothesis or to collect more data,…

Machine Learning · Statistics 2023-07-21 Aleksandr Podkopaev , Aaditya Ramdas

Testing for the conditional independence structure in data is a fundamental and critical task in statistics and machine learning, which finds natural applications in causal discovery - a highly relevant problem to many scientific…

Machine Learning · Statistics 2025-03-03 Bao Duong , Nu Hoang , Thin Nguyen

The partial copula provides a method for describing the dependence between two random variables $X$ and $Y$ conditional on a third random vector $Z$ in terms of nonparametric residuals $U_1$ and $U_2$. This paper develops a nonparametric…

Statistics Theory · Mathematics 2021-04-30 Lasse Petersen , Niels Richard Hansen

We consider settings in which the data of interest correspond to pairs of ordered times, e.g, the birth times of the first and second child, the times at which a new user creates an account and makes the first purchase on a website, and the…

Methodology · Statistics 2020-11-19 Tamara Fernández , Wenkai Xu , Marc Ditzhaus , Arthur Gretton

A new non parametric approach to the problem of testing the independence of two random process is developed. The test statistic is the Hilbert Schmidt Independence Criterion (HSIC), which was used previously in testing independence for…

Machine Learning · Statistics 2014-06-18 Kacper Chwialkowski , Arthur Gretton

For a set of dependent random variables, without stationary or the strong mixing assumptions, we derive the asymptotic independence between their sums and maxima. Then we apply this result to high-dimensional testing problems, where we…

Methodology · Statistics 2022-05-12 Long Feng , Tiefeng Jiang , Xiaoyun Li , Binghui Liu

In this paper, we consider the problem of testing independence in high-dimensional settings with missing data. Building upon a recently proposed Kendall-based statistic, we introduce two new modifications specifically designed to…

Methodology · Statistics 2026-04-28 Marija Cuparić , Bojana Milošević , Jelena Radojević

Independence testing is a classical statistical problem that has been extensively studied in the batch setting when one fixes the sample size before collecting data. However, practitioners often prefer procedures that adapt to the…

Machine Learning · Statistics 2025-05-21 Aleksandr Podkopaev , Patrick Blöbaum , Shiva Prasad Kasiviswanathan , Aaditya Ramdas

We propose a new method to test conditional independence of two real random variables $Y$ and $Z$ conditionally on an arbitrary third random variable $X$. %with $F_{.|.}$ representing conditional distribution functions, The partial copula…

Statistics Theory · Mathematics 2011-01-25 Wicher Bergsma

Spherical and hyperspherical data are commonly encountered in diverse applied research domains, underscoring the vital task of assessing independence within such data structures. In this context, we investigate the properties of test…

Methodology · Statistics 2024-01-23 Marija Cuparić , Bruno Ebner , Bojana Milošević

Conditional independence testing is a key problem required by many machine learning and statistics tools. In particular, it is one way of evaluating the usefulness of some features on a supervised prediction problem. We propose a novel…

Machine Learning · Statistics 2019-08-02 Marco Henrique de Almeida Inácio , Rafael Izbicki , Rafael Bassi Stern

Tests of conditional independence (CI) underpin a number of important problems in machine learning and statistics, from causal discovery to evaluation of predictor fairness and out-of-distribution robustness. Shah and Peters (2020) showed…

Machine Learning · Statistics 2025-12-17 Zheng He , Roman Pogodin , Yazhe Li , Namrata Deka , Arthur Gretton , Danica J. Sutherland

Testing conditional independence between two random vectors given a third is a fundamental and challenging problem in statistics, particularly in multivariate nonparametric settings due to the complexity of conditional structures. We…

Machine Learning · Statistics 2025-07-28 Chenxuan He , Yuan Gao , Liping Zhu , Jian Huang

Dette, Siburg, and Stoimenov (2013) introduced a copula-based measure of dependence, which implies independence if it vanishes and is equal to 1 if one variable is a measurable function of the other. For continuous distributions, the…

Statistics Theory · Mathematics 2026-02-17 Mona Azadkia , Holger Dette

We propose new statistical tests, in high-dimensional settings, for testing the independence of two random vectors and their conditional independence given a third random vector. The key idea is simple, i.e., we first transform each…

Methodology · Statistics 2026-01-28 Jinyuan Chang , Yue Du , Jing He , Qiwei Yao