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Attention mechanisms take an expectation of a data representation with respect to probability weights. This creates summary statistics that focus on important features. Recently, (Martins et al. 2020, 2021) proposed continuous attention…

Machine Learning · Computer Science 2021-11-16 Alexander Moreno , Supriya Nagesh , Zhenke Wu , Walter Dempsey , James M. Rehg

Systems whose time evolutions are entirely deterministic can nevertheless be studied probabilistically, i.e. in terms of the evolution of probability distributions rather than individual trajectories. This approach is central to the…

Dynamical Systems · Mathematics 2019-09-06 S. Richard Taylor

We address the problem of learning of continuous exponential family distributions with unbounded support. While a lot of progress has been made on learning of Gaussian graphical models, we still lack scalable algorithms for reconstructing…

Machine Learning · Computer Science 2022-03-01 Christopher X. Ren , Sidhant Misra , Marc Vuffray , Andrey Y. Lokhov

Deep generative models open new avenues for simulating realistic genomic data while preserving privacy and addressing data accessibility constraints. While previous studies have primarily focused on generating gene expression or haplotype…

Genomics · Quantitative Biology 2025-08-14 Sihan Xie , Thierry Tribout , Didier Boichard , Blaise Hanczar , Julien Chiquet , Eric Barrey

Deep generative models offer powerful tools for multivariate data analysis, but their black-box architectures are often unidentified and difficult to interpret. We introduce the Deep Discrete Encoder (DDE) Copula, an identifiable and…

Machine Learning · Statistics 2026-05-28 Joseph Feldman , Yuqi Gu

To construct models of large, multivariate complex systems, such as those in biology, one needs to constrain which variables are allowed to interact. This can be viewed as detecting "local" structures among the variables. In the context of…

Data Analysis, Statistics and Probability · Physics 2023-10-19 Mahajabin Rahman , Ilya Nemenman

Many high dimensional and high-throughput biological datasets have complex sample correlation structures, which include longitudinal and multiple tissue data, as well as data with multiple treatment conditions or related individuals. These…

Methodology · Statistics 2018-08-20 Chris McKennan , Dan Nicolae

Neuro-Evolution is a field of study that has recently gained significantly increased traction in the deep learning community. It combines deep neural networks and evolutionary algorithms to improve and/or automate the construction of neural…

Neural and Evolutionary Computing · Computer Science 2020-10-05 Marijn van Knippenberg , Vlado Menkovski , Sergio Consoli

Boolean Delay Equations (BDEs) are semi-discrete dynamical models with Boolean-valued variables that evolve in continuous time. Systems of BDEs can be classified into conservative or dissipative, in a manner that parallels the…

Cellular Automata and Lattice Gases · Physics 2015-06-26 Michael Ghil , Ilya Zaliapin , Barbara Coluzzi

Feature construction can contribute to comprehensibility and performance of machine learning models. Unfortunately, it usually requires exhaustive search in the attribute space or time-consuming human involvement to generate meaningful…

Machine Learning · Computer Science 2023-01-24 Boštjan Vouk , Matej Guid , Marko Robnik-Šikonja

Traditional clustering methods often perform clustering with low-level indiscriminative representations and ignore relationships between patterns, resulting in slight achievements in the era of deep learning. To handle this problem, we…

Machine Learning · Computer Science 2019-05-07 Jianlong Chang , Yiwen Guo , Lingfeng Wang , Gaofeng Meng , Shiming Xiang , Chunhong Pan

The variation distance closure of an exponential family with a convex set of canonical parameters is described, assuming no regularity conditions. The tools are the concepts of convex core of a measure and extension of an exponential…

Probability · Mathematics 2007-05-23 Imre Csiszar , Frantisek Matus

Machine- and deep-learning approaches for biological sequences depend critically on transforming raw DNA, RNA, and protein FASTA files into informative numerical representations. However, this process is often fragmented across multiple…

Genomics · Quantitative Biology 2025-12-01 Hamid Ismail , Marwan Bikdash

The evolution processes of complex systems carry key information in the systems' functional properties. Applying machine learning algorithms, we demonstrate that the historical formation process of various networked complex systems can be…

Physics and Society · Physics 2024-03-25 Junya Wang , Yi-Jiao Zhang , Cong Xu , Jiaze Li , Jiachen Sun , Jiarong Xie , Ling Feng , Tianshou Zhou , Yanqing Hu

Deterministic variables are variables that are fully explained by one or more parent variables. They commonly arise when a variable has been algebraically constructed from one or more parent variables, as with composite variables, and in…

Transcription factors (TFs) regulate gene expression through complex and co-operative mechanisms. While many TFs act together, the logic underlying TFs binding and their interactions is not fully understood yet. Most current approaches for…

Machine Learning · Computer Science 2026-03-13 Pietro Demurtas , Ferdinando Zanchetta , Giovanni Perini , Rita Fioresi

Producing probabilistic forecasts for large collections of similar and/or dependent time series is a practically relevant and challenging task. Classical time series models fail to capture complex patterns in the data, and multivariate…

Machine Learning · Statistics 2019-05-30 Yuyang Wang , Alex Smola , Danielle C. Maddix , Jan Gasthaus , Dean Foster , Tim Januschowski

Asynchronous Time Series is a multivariate time series where all the channels are observed asynchronously-independently, making the time series extremely sparse when aligning them. We often observe this effect in applications with complex…

Machine Learning · Computer Science 2022-08-25 Vijaya Krishna Yalavarthi , Johannes Burchert , Lars Schmidt-Thieme

A structural causal model is made of endogenous (manifest) and exogenous (latent) variables. We show that endogenous observations induce linear constraints on the probabilities of the exogenous variables. This allows to exactly map a causal…

Artificial Intelligence · Computer Science 2020-08-04 Marco Zaffalon , Alessandro Antonucci , Rafael Cabañas

We present an approach to semi-supervised learning based on an exponential family characterization. Our approach generalizes previous work on coupled priors for hybrid generative/discriminative models. Our model is more flexible and natural…

Machine Learning · Computer Science 2010-03-04 Arvind Agarwal , Hal Daume
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