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We systematically evaluate the performance of deep learning models in the presence of diseases not labeled for or present during training. First, we evaluate whether deep learning models trained on a subset of diseases (seen diseases) can…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Siyu Shi , Ishaan Malhi , Kevin Tran , Andrew Y. Ng , Pranav Rajpurkar

The rapid integration of Artificial Intelligence (AI) into medical diagnostics has raised pressing concerns about patient privacy, especially when sensitive imaging data must be transferred, stored, or processed. In this paper, we propose a…

Cryptography and Security · Computer Science 2025-07-30 Abdullah Al Siam , Sadequzzaman Shohan

Recently, deep learning has started to play an essential role in healthcare applications, including image search in digital pathology. Despite the recent progress in computer vision, significant issues remain for image searching in…

Image and Video Processing · Electrical Eng. & Systems 2023-04-19 Pooria Mazaheri , Azam Asilian Bidgoli , Shahryar Rahnamayan , H. R. Tizhoosh

Deep learning models were frequently reported to learn from shortcuts like dataset biases. As deep learning is playing an increasingly important role in the modern healthcare system, it is of great need to combat shortcut learning in…

Image and Video Processing · Electrical Eng. & Systems 2022-08-05 Luyang Luo , Dunyuan Xu , Hao Chen , Tien-Tsin Wong , Pheng-Ann Heng

Do very high accuracies of deep networks suggest pride of effective AI or are deep networks prejudiced? Do they suffer from in-group biases (own-race-bias and own-age-bias), and mimic the human behavior? Is in-group specific information…

Computer Vision and Pattern Recognition · Computer Science 2019-06-21 Shruti Nagpal , Maneet Singh , Richa Singh , Mayank Vatsa

AI systems frequently exhibit and amplify social biases, leading to harmful consequences in critical areas. This study introduces a novel encoder-decoder approach that leverages model gradients to learn a feature neuron encoding societal…

Machine Learning · Computer Science 2026-03-10 Jonathan Drechsel , Steffen Herbold

Deep neural networks have shown impressive performance for image-based disease detection. Performance is commonly evaluated through clinical validation on independent test sets to demonstrate clinically acceptable accuracy. Reporting good…

Image and Video Processing · Electrical Eng. & Systems 2023-09-18 Mobarakol Islam , Zeju Li , Ben Glocker

Undesirable biases encoded in the data are key drivers of algorithmic discrimination. Their importance is widely recognized in the algorithmic fairness literature, as well as legislation and standards on anti-discrimination in AI. Despite…

Machine Learning · Computer Science 2025-07-15 Marina Ceccon , Giandomenico Cornacchia , Davide Dalle Pezze , Alessandro Fabris , Gian Antonio Susto

Systematic mislabelling affecting specific subgroups (i.e., label bias) in medical imaging datasets represents an understudied issue concerning the fairness of medical AI systems. In this work, we investigated how size and separability of…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Emma A. M. Stanley , Raghav Mehta , Mélanie Roschewitz , Nils D. Forkert , Ben Glocker

Identifying and mitigating bias in deep learning algorithms has gained significant popularity in the past few years due to its impact on the society. Researchers argue that models trained on balanced datasets with good representation…

Computer Vision and Pattern Recognition · Computer Science 2021-08-17 Puspita Majumdar , Surbhi Mittal , Richa Singh , Mayank Vatsa

While many studies have assessed the fairness of AI algorithms in the medical field, the causes of differences in prediction performance are often unknown. This lack of knowledge about the causes of bias hampers the efficacy of bias…

Image and Video Processing · Electrical Eng. & Systems 2023-08-11 Nina Weng , Siavash Bigdeli , Eike Petersen , Aasa Feragen

Machine learning models have achieved high overall accuracy in medical image analysis. However, performance disparities on specific patient groups pose challenges to their clinical utility, safety, and fairness. This can affect known…

Machine Learning · Computer Science 2024-10-23 Vincent Olesen , Nina Weng , Aasa Feragen , Eike Petersen

Predictive algorithms have a powerful potential to offer benefits in areas as varied as medicine or education. However, these algorithms and the data they use are built by humans, consequently, they can inherit the bias and prejudices…

Human-Computer Interaction · Computer Science 2022-03-22 Cristina Manresa-Yee , Silvia Ramis

Deep Learning models have transformed various domains, including the healthcare sector, particularly biomedical image classification by learning intricate features and enabling accurate diagnostics pertaining to complex diseases. Recent…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Imran Ashraf , Mukhtar Ullah , Muhammad Faisal Nadeem , Muhammad Nouman Noor

The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Ke Zou , Zhihao Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Artificial intelligence (AI) models trained using medical images for clinical tasks often exhibit bias in the form of disparities in performance between subgroups. Since not all sources of biases in real-world medical imaging data are…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Emma A. M. Stanley , Raissa Souza , Anthony Winder , Vedant Gulve , Kimberly Amador , Matthias Wilms , Nils D. Forkert

In this paper, we propose a novel explanatory framework aimed to provide a better understanding of how face recognition models perform as the underlying data characteristics (protected attributes: gender, ethnicity, age; non-protected…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Andrea Atzori , Gianni Fenu , Mirko Marras

In this study, we introduce the application of causal disparity analysis to unveil intricate relationships and causal pathways between sensitive attributes and the targeted outcomes within real-world observational data. Our methodology…

Computers and Society · Computer Science 2024-08-08 Farnaz Kohankhaki , Shaina Raza , Oluwanifemi Bamgbose , Deval Pandya , Elham Dolatabadi

Machine learning (ML) models may suffer from significant performance disparities between patient groups. Identifying such disparities by monitoring performance at a granular level is crucial for safely deploying ML to each patient.…

Machine Learning · Computer Science 2025-03-14 Alceu Bissoto , Trung-Dung Hoang , Tim Flühmann , Susu Sun , Christian F. Baumgartner , Lisa M. Koch

Machine learning models for medical image analysis often suffer from poor performance on important subsets of a population that are not identified during training or testing. For example, overall performance of a cancer detection model may…

Machine Learning · Computer Science 2019-11-18 Luke Oakden-Rayner , Jared Dunnmon , Gustavo Carneiro , Christopher Ré