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Transformers have revolutionized deep learning based computer vision with improved performance as well as robustness to natural corruptions and adversarial attacks. Transformers are used predominantly for 2D vision tasks, including image…

Computer Vision and Pattern Recognition · Computer Science 2023-12-19 Hemang Chawla , Arnav Varma , Elahe Arani , Bahram Zonooz

With the development of gene sequencing technology, an explosive growth of gene data has been witnessed. And the storage of gene data has become an important issue. Traditional gene data compression methods rely on general software like…

Machine Learning · Computer Science 2023-02-01 Zhanbei Cui , Yu Liao , Tongda Xu , Yan Wang

We show that protein sequences can be thought of as sentences in natural language processing and can be parsed using the existing Quantum Natural Language framework into parameterized quantum circuits of reasonable qubits, which can be…

Beta-turn prediction is useful in protein function studies and experimental design. Although recent approaches using machine-learning techniques such as SVM, neural networks, and K-NN have achieved good results for beta-turn pre-diction,…

Biomolecules · Quantitative Biology 2018-08-14 Chao Fang , Yi Shang , Dong Xu

Machine recognition of an atypical speech like whispered speech, is a challenging task. We introduce whisper-to-natural-speech conversion using sequence-to-sequence approach by proposing enhanced transformer architecture, which uses both…

Audio and Speech Processing · Electrical Eng. & Systems 2021-04-06 Abhishek Niranjan , Mukesh Sharma , Sai Bharath Chandra Gutha , M Ali Basha Shaik

Transformer-based models trained on large and general purpose datasets consisting of molecular strings have recently emerged as a powerful tool for successfully modeling various structure-property relations. Inspired by this success, we…

Biomolecules · Quantitative Biology 2025-04-02 Jerret Ross , Brian Belgodere , Samuel C. Hoffman , Vijil Chenthamarakshan , Jiri Navratil , Youssef Mroueh , Payel Das

Protein language models are a powerful tool for learning protein representations through pre-training on vast protein sequence datasets. However, traditional protein language models lack explicit structural supervision, despite its…

Biomolecules · Quantitative Biology 2024-02-09 Zuobai Zhang , Jiarui Lu , Vijil Chenthamarakshan , Aurélie Lozano , Payel Das , Jian Tang

Recent developments in Natural Language Processing (NLP) demonstrate that large-scale, self-supervised pre-training can be extremely beneficial for downstream tasks. These ideas have been adapted to other domains, including the analysis of…

Computation and Language · Computer Science 2021-02-02 Matthew B. A. McDermott , Brendan Yap , Harry Hsu , Di Jin , Peter Szolovits

Transfer learning with large pretrained transformer-based language models like BERT has become a dominating approach for most NLP tasks. Simply fine-tuning those large language models on downstream tasks or combining it with task-specific…

Computation and Language · Computer Science 2021-08-06 Wenjuan Han , Bo Pang , Yingnian Wu

Transformers are neural networks that revolutionized natural language processing and machine learning. They process sequences of inputs, like words, using a mechanism called self-attention, which is trained via masked language modeling…

Disordered Systems and Neural Networks · Physics 2024-04-17 Riccardo Rende , Federica Gerace , Alessandro Laio , Sebastian Goldt

Both humans and large language models are able to learn language without explicit structural supervision. What inductive biases make this learning possible? We address this fundamental cognitive question by leveraging transformer language…

Computation and Language · Computer Science 2023-10-31 Isabel Papadimitriou , Dan Jurafsky

Designing mechanical mechanisms to trace specific paths is a classic yet notoriously difficult engineering problem, characterized by a vast and complex search space of discrete topologies and continuous parameters. We introduce MechaFormer,…

Machine Learning · Computer Science 2025-08-13 Diana Bolanos , Mohammadmehdi Ataei , Pradeep Kumar Jayaraman

With the increasing release of powerful language models trained on large code corpus (e.g. CodeBERT was trained on 6.4 million programs), a new family of mutation testing tools has arisen with the promise to generate more "natural" mutants…

Software Engineering · Computer Science 2023-03-09 Aayush Garg , Renzo Degiovanni , Mike Papadakis , Yves Le Traon

DNA Language Models, such as GROVER, DNABERT2 and the Nucleotide Transformer, operate on DNA sequences that inherently contain sequencing errors, mutations, and laboratory-induced noise, which may significantly impact model performance.…

Computation and Language · Computer Science 2025-03-04 Hyunwoo Yoo , Haebin Shin , Kaidi Xu , Gail Rosen

The ability to absorb mutations while retaining structure and function, or mutational robustness, is a remarkable property of natural proteins. In this Letter, we use a computational model of organismic evolution [Zeldovich et al, PLOS Comp…

Biomolecules · Quantitative Biology 2008-06-25 Konstantin B. Zeldovich , Eugene I. Shakhnovich

Numerous previous studies have sought to determine to what extent language models, pretrained on natural language text, can serve as useful models of human cognition. In this paper, we are interested in the opposite question: whether we can…

Computation and Language · Computer Science 2024-10-18 Samuel Kiegeland , Ethan Gotlieb Wilcox , Afra Amini , David Robert Reich , Ryan Cotterell

Pretrained language models memorize vast amounts of information, including private and copyrighted data, raising significant safety concerns. Retraining these models after excluding sensitive data is prohibitively expensive, making machine…

Computation and Language · Computer Science 2024-10-04 Minseok Choi , Kyunghyun Min , Jaegul Choo

Discerning how a mutation affects the stability of a protein is central to the study of a wide range of diseases. Machine learning and statistical analysis techniques can inform how to allocate limited resources to the considerable time and…

Quantitative Methods · Quantitative Biology 2018-03-14 Richard Olney , Aaron Tuor , Filip Jagodzinski , Brian Hutchinson

Natural language is one of the most intuitive ways to express human intent. However, translating instructions and commands towards robotic motion generation and deployment in the real world is far from being an easy task. The challenge of…

Robotics · Computer Science 2022-09-20 Arthur Bucker , Luis Figueredo , Sami Haddadin , Ashish Kapoor , Shuang Ma , Sai Vemprala , Rogerio Bonatti

Metal-Organic Frameworks (MOFs) are materials with a high degree of porosity that can be used for applications in energy storage, water desalination, gas storage, and gas separation. However, the chemical space of MOFs is close to an…

Machine Learning · Computer Science 2022-10-26 Zhonglin Cao , Rishikesh Magar , Yuyang Wang , Amir Barati Farimani