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Neuroscience and artificial intelligence (AI) both face the challenge of interpreting high-dimensional neural data, where the comparative analysis of such data is crucial for revealing shared mechanisms and differences between these complex…

Neurons and Cognition · Quantitative Biology 2025-09-16 Yiqing Bo , Ansh Soni , Sudhanshu Srivastava , Meenakshi Khosla

As deep learning systems are scaled up to many billions of parameters, relating their internal structure to external behaviors becomes very challenging. Although daunting, this problem is not new: Neuroscientists and cognitive scientists…

Partially inspired by features of computation in visual cortex, deep neural networks compute hierarchical representations of their inputs. While these networks have been highly successful in machine learning, it remains unclear to what…

Neurons and Cognition · Quantitative Biology 2019-11-20 Jianghong Shi , Eric Shea-Brown , Michael A. Buice

The analysis of biophysical neural networks (BNNs) has been a longstanding focus in computational neuroscience. A central yet unresolved challenge in BNN analysis lies in deciphering the correlations between neuronal and synaptic dynamics,…

Machine Learning · Computer Science 2024-10-16 Youngmok Ha , Yongjoo Kim , Hyun Jae Jang , Seungyeon Lee , Eunji Pak

A common approach in neuroscience is to study neural representations as a means to understand a system -- increasingly, by relating the neural representations to the internal representations learned by computational models. However, a…

Neurons and Cognition · Quantitative Biology 2025-08-14 Andrew Kyle Lampinen , Stephanie C. Y. Chan , Yuxuan Li , Katherine Hermann

Deep learning methods have recently made notable advances in the tasks of classification and representation learning. These tasks are important for brain imaging and neuroscience discovery, making the methods attractive for porting to a…

Neural and Evolutionary Computing · Computer Science 2014-02-20 Sergey M. Plis , Devon R. Hjelm , Ruslan Salakhutdinov , Vince D. Calhoun

Estimating treatment effects from observational data is challenging due to two main reasons: (a) hidden confounding, and (b) covariate mismatch (control and treatment groups not having identical distributions). Long lines of works exist…

Machine Learning · Computer Science 2025-04-30 Praharsh Nanavati , Ranjitha Prasad , Karthikeyan Shanmugam

Complex networks are frequently employed to model physical or virtual complex systems. When certain entities exist across multiple systems simultaneously, unveiling their corresponding relationships across the networks becomes crucial. This…

Physics and Society · Physics 2025-04-16 Rui Tang , Ziyun Yong , Shuyu Jiang , Xingshu Chen , Yaofang Liu , Yi-Cheng Zhang , Gui-Quan Sun , Wei Wang

Model stitching (Lenc & Vedaldi 2015) is a compelling methodology to compare different neural network representations, because it allows us to measure to what degree they may be interchanged. We expand on a previous work from Bansal,…

Machine Learning · Computer Science 2023-09-04 Adriano Hernandez , Rumen Dangovski , Peter Y. Lu , Marin Soljacic

Big science initiatives are trying to reconstruct and model the brain by attempting to simulate brain tissue at larger scales and with increasingly more biological detail than previously thought possible. The exponential growth of parallel…

Performance · Computer Science 2020-06-25 Francesco Cremonesi , Georg Hager , Gerhard Wellein , Felix Schürmann

Neural networks encode inputs as high-dimensional vectors, known as representations, that capture how models process data by encoding task-relevant structure and semantics. Representation alignment refers to the degree to which different…

Computational Geometry · Computer Science 2026-05-26 Xinyuan Yan , Rita Sevastjanova , Mennatallah El-Assady , Bei Wang

Despite the centrality of the notion of representation in neuroscience, the field lacks a unified framework for the concepts used to characterize representation, leading to disparate use of both terminology and measures associated with it.…

Neurons and Cognition · Quantitative Biology 2026-04-27 Stephan Pohl , Edgar Y. Walker , David L. Barack , Jennifer Lee , Rachel N. Denison , Ned Block , Florent Meyniel , Wei Ji Ma

Network representations of the nervous system have been useful for the understanding of brain phenomena such as perception, motor coordination, and memory. Although brains are composed of both neurons and glial cells, neuron-glial networks…

Neurons and Cognition · Quantitative Biology 2024-11-14 Marco Peña-Garcia , Francesco Peña-Garcia , Nelson Castro , Walter Cabrera-Febola

Task-based modeling with recurrent neural networks (RNNs) has emerged as a popular way to infer the computational function of different brain regions. These models are quantitatively assessed by comparing the low-dimensional neural…

Neurons and Cognition · Quantitative Biology 2019-12-06 Niru Maheswaranathan , Alex H. Williams , Matthew D. Golub , Surya Ganguli , David Sussillo

We cast shape matching as metric learning with convolutional networks. We break the end-to-end process of image representation into two parts. Firstly, well established efficient methods are chosen to turn the images into edge maps.…

Computer Vision and Pattern Recognition · Computer Science 2018-07-27 Filip Radenović , Giorgos Tolias , Ondřej Chum

The need for more transparency of the decision-making processes in artificial neural networks steadily increases driven by their applications in safety critical and ethically challenging domains such as autonomous driving or medical…

Neural and Evolutionary Computing · Computer Science 2020-05-12 Richard Meyes , Constantin Waubert de Puiseau , Andres Posada-Moreno , Tobias Meisen

Deep neural networks have reached human-level performance on many computer vision tasks. However, the objectives used to train these networks enforce only that similar images are embedded at similar locations in the representation space,…

Computer Vision and Pattern Recognition · Computer Science 2023-09-27 Lukas Muttenthaler , Lorenz Linhardt , Jonas Dippel , Robert A. Vandermeulen , Katherine Hermann , Andrew K. Lampinen , Simon Kornblith

Social network analysis is an important problem in data mining. A fundamental step for analyzing social networks is to encode network data into low-dimensional representations, i.e., network embeddings, so that the network topology…

Social and Information Networks · Computer Science 2019-04-19 Qiaoyu Tan , Ninghao Liu , Xia Hu

Understanding the complexity of biological neural networks like the human brain is one of the scientific challenges of our century. The organization of the brain can be described at different levels, ranging from small neural networks to…

Neurons and Cognition · Quantitative Biology 2018-05-23 Stefano De Blasi

Comparing different neural network representations and determining how representations evolve over time remain challenging open questions in our understanding of the function of neural networks. Comparing representations in neural networks…

Machine Learning · Statistics 2018-10-25 Ari S. Morcos , Maithra Raghu , Samy Bengio