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Topological correctness plays a critical role in many image segmentation tasks, yet most networks are trained using pixel-wise loss functions, such as Dice, neglecting topological accuracy. Existing topology-aware methods often lack robust…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Laurin Lux , Alexander H. Berger , Alexander Weers , Nico Stucki , Daniel Rueckert , Ulrich Bauer , Johannes C. Paetzold

Topological data analysis (TDA) is a relatively new field that is gaining rapid adoption due to its robustness and ability to effectively describe complex datasets by quantifying geometric information. In imaging contexts, TDA typically…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Aaryam Sharma

In digital pathology, segmenting densely distributed objects like glands and nuclei is crucial for downstream analysis. Since detailed pixel-wise annotations are very time-consuming, we need semi-supervised segmentation methods that can…

Image and Video Processing · Electrical Eng. & Systems 2024-07-18 Meilong Xu , Xiaoling Hu , Saumya Gupta , Shahira Abousamra , Chao Chen

Skin cancer is one of the most common cancers in the United States. As technological advancements are made, algorithmic diagnosis of skin lesions is becoming more important. In this paper, we develop algorithms for segmenting the actual…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Yu-Min Chung , Chuan-Shen Hu , Austin Lawson , Clifford Smyth

Accurate medical image segmentation is essential for diagnosis and treatment planning of diseases. Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they are…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Ran Gu , Guotai Wang , Tao Song , Rui Huang , Michael Aertsen , Jan Deprest , Sébastien Ourselin , Tom Vercauteren , Shaoting Zhang

Precise segmentation of organs and tumors plays a crucial role in clinical applications. It is a challenging task due to the irregular shapes and various sizes of organs and tumors as well as the significant class imbalance between the…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Ziqiang Li , Hong Pan , Yaping Zhu , A. K. Qin

Pathological diagnosis is the gold standard for cancer diagnosis, but it is labor-intensive, in which tasks such as cell detection, classification, and counting are particularly prominent. A common solution for automating these tasks is…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Anyu Mao , Jialun Wu , Xinrui Bao , Zeyu Gao , Tieliang Gong , Chen Li

Separating overlapped nuclei is a major challenge in histopathology image analysis. Recently published approaches have achieved promising overall performance on nuclei segmentation; however, their performance on separating overlapped nuclei…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Haotian Wang , Aleksandar Vakanski , Changfa Shi , Min Xian

Instance segmentation of nuclei and glands in the histology images is an important step in computational pathology workflow for cancer diagnosis, treatment planning and survival analysis. With the advent of modern hardware, the recent…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Esha Sadia Nasir , Arshi Perviaz , Muhammad Moazam Fraz

Curvilinear structure segmentation is important in medical imaging, quantifying structures such as vessels, airways, neurons, or organ boundaries in 2D slices. Segmentation via pixel-wise classification often fails to capture the small and…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Manxi Lin , Zahra Bashir , Martin Grønnebæk Tolsgaard , Anders Nymark Christensen , Aasa Feragen

Segmentation of ultra-high resolution images is increasingly demanded, yet poses significant challenges for algorithm efficiency, in particular considering the (GPU) memory limits. Current approaches either downsample an ultra-high…

Computer Vision and Pattern Recognition · Computer Science 2021-03-04 Wuyang Chen , Ziyu Jiang , Zhangyang Wang , Kexin Cui , Xiaoning Qian

Ultrasound (US) is the primary imaging technique for the diagnosis of thyroid cancer. However, accurate identification of nodule malignancy is a challenging task that can elude less-experienced clinicians. Recently, many computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Van T. Manh , Jianqiao Zhou , Xiaohong Jia , Zehui Lin , Wenwen Xu , Zihan Mei , Yijie Dong , Xin Yang , Ruobing Huang , Dong Ni

Automated pathology segmentation remains a valuable diagnostic tool in clinical practice. However, collecting training data is challenging. Semi-supervised approaches by combining labelled and unlabelled data can offer a solution to data…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Haochuan Jiang , Agisilaos Chartsias , Xinheng Zhang , Giorgos Papanastasiou , Scott Semple , Mark Dweck , David Semple , Rohan Dharmakumar , Sotirios A. Tsaftaris

Liver landmarks provide crucial anatomical guidance to the surgeon during laparoscopic liver surgery to minimize surgical risk. However, the tubular structural properties of landmarks and dynamic intraoperative deformations pose significant…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Ruize Cui , Jiaan Zhang , Jialun Pei , Kai Wang , Pheng-Ann Heng , Jing Qin

Accurate segmentation of clustered microcalcifications in mammography is crucial for the diagnosis and treatment of breast cancer. Despite exhibiting expert-level accuracy, recent deep learning advancements in medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Ke Wang , Zanting Ye , Xiang Xie , Haidong Cui , Tao Chen , Banteng Liu

Accurate nuclei segmentation in histopathological images is crucial for cancer diagnosis. Automating this process offers valuable support to clinical experts, as manual annotation is time-consuming and prone to human errors. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-06-13 Ayush Roy , Payel Pramanik , Dmitrii Kaplun , Sergei Antonov , Ram Sarkar

Mucous glands lesions analysis and assessing of malignant potential of colon polyps are very important tasks of surgical pathology. However, differential diagnosis of colon polyps often seems impossible by classical methods and it is…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 A. Khvostikov , A. Krylov , O. Kharlova , N. Oleynikova , I. Mikhailov , P. Malkov

Accurate segmentation of thalamic nuclei from magnetic resonance images is important due to the distinct roles of these nuclei in overall brain function and to their differential involvement in neurological and psychiatric disorders.…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Anqi Feng , Zhangxing Bian , Samuel W. Remedios , Savannah P. Hays , Blake E. Dewey , Alexa Colinco , Jiachen Zhuo , Dan Benjamini , Jerry L. Prince

Breast tumor segmentation provides accurate tumor boundary, and serves as a key step toward further cancer quantification. Although deep learning-based approaches have been proposed and achieved promising results, existing approaches have…

Image and Video Processing · Electrical Eng. & Systems 2020-02-05 Bryar Shareef , Min Xian , Aleksandar Vakanski

This paper proposes a novel topological learning framework that integrates networks of different sizes and topology through persistent homology. Such challenging task is made possible through the introduction of a computationally efficient…

Neurons and Cognition · Quantitative Biology 2023-01-30 Tananun Songdechakraiwut , Moo K. Chung