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As in many other areas of science, systems biology makes extensive use of statistical association and significance estimates in contingency tables, a type of categorical data analysis known in this field as enrichment (also…

Quantitative Methods · Quantitative Biology 2011-11-10 Ricardo Vêncio , Ilya Shmulevich

Randomization tests allow simple and unambiguous tests of null hypotheses, by comparing observed data to a null ensemble in which experimentally-controlled variables are randomly resampled. In behavioral and neuroscience experiments,…

Methodology · Statistics 2023-11-08 Kenneth D. Harris , Kevin J. Miller

A novel confidence interval estimator is proposed for the risk difference in noninferiority binomial trials. The confidence interval is consistent with an exact unconditional test that preserves the type-I error, and has improved power,…

Methodology · Statistics 2021-10-18 Nour Hawila , Arthur Berg

Statistical methods for automatically identifying dependent word pairs (i.e. dependent bigrams) in a corpus of natural language text have traditionally been performed using asymptotic tests of significance. This paper suggests that Fisher's…

cmp-lg · Computer Science 2008-02-03 Ted Pedersen

In this paper, we propose an easy-to-implement residual-based specification testing procedure for detecting structural changes in factor models, which is powerful against both smooth and abrupt structural changes with unknown break dates.…

Econometrics · Economics 2025-01-22 Bin Peng , Liangjun Su , Yayi Yan

The analysis of contingency tables is a powerful statistical tool used in experiments with categorical variables. This study improves parts of the theory underlying the use of contingency tables. Specifically, the linkage disequilibrium…

Statistics Theory · Mathematics 2022-05-04 Friedrich Teuscher

Statistical data is often analyzed as a contingency table, sometimes with empty cells called zeros. Such sparse tables can be due to scarse observations classified in numerous categories, as for example in genetic association studies. Thus,…

Statistics Theory · Mathematics 2010-07-28 Audrey Finkler

Statistical data is often analyzed as a contingency table, sometimes with empty cells called zeros. Such sparse tables can be due to scarse observations classified in numerous categories, as for example in genetic association studies. Thus,…

Statistics Theory · Mathematics 2010-07-28 Audrey Finkler

Given a set of incomplete observations, we study the nonparametric problem of testing whether data are Missing Completely At Random (MCAR). Our first contribution is to characterise precisely the set of alternatives that can be…

Statistics Theory · Mathematics 2022-05-19 Thomas B Berrett , Richard J Samworth

Linear combinations of multinomial probabilities, such as those resulting from contingency tables, are of use when evaluating classification system performance. While large sample inference methods for these combinations exist, small sample…

Methodology · Statistics 2021-04-20 Katherine A. Batterton , Christine M. Schubert , Richard L. Warr

In confirmatory clinical trials with small sample sizes, hypothesis tests based on asymptotic distributions are often not valid and exact non-parametric procedures are applied instead. However, the latter are based on discrete test…

Methodology · Statistics 2018-02-22 Robin Ristl , Dong Xi , Ekkehard Glimm , Martin Posch

This paper shows that the problem of testing hypotheses in moment condition models without any assumptions about identification may be considered as a problem of testing with an infinite-dimensional nuisance parameter. We introduce a…

Statistics Theory · Mathematics 2014-09-24 Isaiah Andrews , Anna Mikusheva

We present a new approach for random sampling of contingency tables of any size and constraints based on a recently introduced $\textit{probabilistic divide-and-conquer}$ technique. A simple exact sampling algorithm is presented for…

Statistics Theory · Mathematics 2016-03-01 Stephen DeSalvo , James Y. Zhao

In hypothesis testing problems the property of strict unbiasedness describes whether a test is able to discriminate, in the sense of a difference in power, between any distribution in the null hypothesis space and any distribution in the…

Statistics Theory · Mathematics 2025-06-11 Andrew McCormack

The t-statistic is a widely-used scale-invariant statistic for testing the null hypothesis that the mean is zero. Martingale methods enable sequential testing with the t-statistic at every sample size, while controlling the probability of…

Statistics Theory · Mathematics 2025-02-10 Peter D. Grünwald , Wouter M. Koolen

In this paper we study saturated fractions of factorial designs under the perspective of Algebraic Statistics. We define a criterion to check whether a fraction is saturated or not with respect to a given model. The proposed criterion is…

Statistics Theory · Mathematics 2013-05-01 Roberto Fontana , Fabio Rapallo , Maria-Piera Rogantin

Rule based classifiers that use the presence and absence of key sub-strings to make classification decisions have a natural mechanism for quantifying the uncertainty of their precision. For a binary classifier, the key insight is to treat…

Machine Learning · Computer Science 2020-05-20 James Nutaro , Ozgur Ozmen

The task of monitoring for a change in the mean of a sequence of Bernoulli random variables has been widely studied. However most existing approaches make at least one of the following assumptions, which may be violated in many real-world…

Computation · Statistics 2015-05-08 Gordon J. Ross , Dimitris K. Tasoulis , Niall M. Adams

Spatial interaction patterns such as segregation and association can be tested using nearest neighbor contingency tables (NNCTs). We introduce new cell-specific (or pairwise) and overall segregation tests and determine their asymptotic…

Methodology · Statistics 2013-12-06 Elvan Ceyhan

The analysis of incomplete contingency tables is a practical and an interesting problem. In this paper, we provide characterizations for the various missing mechanisms of a variable in terms of response and non-response odds for two and…

Methodology · Statistics 2018-11-27 S. Ghosh , P. Vellaisamy