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Kernel smoothers are essential tools for data analysis due to their ability to convey complex statistical information with concise graphical visualisations. Their inclusion in the base distribution and in the many user-contributed add-on…

Computation · Statistics 2024-09-17 Tarn Duong

Due to their flexibility and superior performance, machine learning models frequently complement and outperform traditional statistical survival models. However, their widespread adoption is hindered by a lack of user-friendly tools to…

BHAM is a freely avaible R pakcage that implments Bayesian hierarchical additive models for high-dimensional clinical and genomic data. The package includes functions that generalized additive model, and Cox additive model with the…

Computation · Statistics 2022-07-07 Boyi Guo , Nengjun Yi

Parcellations are fundamental tools in neuroanatomy, allowing researchers to place functional imaging and molecular data within a structural context in the brain. Visualizing these parcellations is critical to guide biological understanding…

Tissues and Organs · Quantitative Biology 2022-01-26 Giuseppe A. D'Agostino , Sarah R. Langley

Academic Clinical Trial Units frequently face fragmented statistical workflows, leading to duplicated effort, limited collaboration, and inconsistent analytical practices. To address these challenges within an oncology Clinical Trial Unit,…

As an alternative to using administrative areas for the evaluation of small-area health inequalities, Sauzet et al. suggested to take an ego-centred approach and model the spatial correlation structure of health outcomes at the individual…

Computation · Statistics 2024-05-14 Julia Dyck , Jan-Ole Koslik , Odile Sauzet

High-dimensional prediction considers data with more variables than samples. Generic research goals are to find the best predictor or to select variables. Results may be improved by exploiting prior information in the form of co-data,…

Methodology · Statistics 2022-05-17 Mirrelijn M. van Nee , Lodewyk F. A. Wessels , Mark A. van de Wiel

The R package rts2 provides data manipulation and model fitting tools for Log Gaussian Cox Process (LGCP) models. LGCP models are a key method for disease and other types of surveillance, and provide a means of predicting risk across an…

Computation · Statistics 2024-03-15 Samuel I Watson

The RooStatsCms (RSC) software framework allows analysis modelling and combination, statistical studies together with the access to sophisticated graphics routines for results visualisation. The goal of the project is to complement the…

Data Analysis, Statistics and Probability · Physics 2010-03-04 D. Piparo , Gregory Schott , G. Quast

Continuous-variable (CV) quantum information processing is a promising candidate for large-scale fault-tolerant quantum computation. However, analysis of CV quantum process relies mostly on direct computation of the evolution of operators…

Motivation: In recent years, the availability of multi-omics data has increased substantially. Multi-omics data integration methods mainly aim to leverage different molecular layers to gain a complete molecular description of biological…

Methodology · Statistics 2026-01-28 Alessio Albanese , Wouter Kohlen , Pariya Behrouzi

In this paper, we present a new R package COREclust dedicated to the detection of representative variables in high dimensional spaces with a potentially limited number of observations. Variable sets detection is based on an original graph…

Mathematical Software · Computer Science 2018-05-28 Camille Champion , Anne-Claire Brunet , Jean-Michel Loubes , Laurent Risser

This paper introduces cozy, a tool for analyzing and visualizing differences between two versions of a software binary. The primary use case for cozy is validating "micropatches": small binary or assembly-level patches inserted into…

Software Engineering · Computer Science 2025-09-04 Caleb Helbling , Graham Leach-Krouse , Sam Lasser , Greg Sullivan

This paper introduces TimeDepFrail, an R package designed to implement time-varying shared frailty models by extending the traditional shared frailty Cox model to allow the frailty term to evolve across time intervals. These models are…

Computation · Statistics 2025-01-23 Alessandra Ragni , Giulia Romani , Chiara Masci

Genetic programming is an optimization algorithm inspired by evolution which automatically evolves the structure of interpretable computer programs. The fitness evaluation in genetic programming suffers from high computational requirements,…

Neural and Evolutionary Computing · Computer Science 2025-04-16 Sigur de Vries , Sander W. Keemink , Marcel A. J. van Gerven

The Cox proportional hazards model stands as a widely-used semi-parametric approach for survival analysis in medical research and many other fields. Numerous extensions of the Cox model have further expanded its versatility. Statistical…

Computation · Statistics 2023-10-26 Jianxiao Yang , Martijn J. Schuemie , Marc A. Suchard

Case-cohort design, an outcome-dependent sampling design for censored survival data, is increasingly used in biomedical research. The development of asymptotic theory for a case-cohort design in the current literature primarily relies on…

Statistics Theory · Mathematics 2012-04-13 Bin Nan , Jon A. Wellner

Advancements in medical informatics tools and high-throughput biological experimentation make large-scale biomedical data routinely accessible to researchers. Competing risks data are typical in biomedical studies where individuals are at…

Computation · Statistics 2021-11-30 Eric S Kawaguchi , Jenny I Shen , Gang Li , Marc A Suchard

Objectives Extraction of PICO (Populations, Interventions, Comparison, and Outcomes) entities is fundamental to evidence retrieval. We present a novel method PICOX to extract overlapping PICO entities. Materials and Methods PICOX first…

Information Retrieval · Computer Science 2024-01-17 Gongbo Zhang , Yiliang Zhou , Yan Hu , Hua Xu , Chunhua Weng , Yifan Peng