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Deep learning has excelled in medical image classification, but its clinical application is limited by poor interpretability. Capsule networks, known for encoding hierarchical relationships and spatial features, show potential in addressing…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Xinyu Geng , Jiaming Wang , Jun Xu

Segmentation of nuclei regions from histological images is an important task for automated computer-aided analysis of histological images, particularly in the presence of impermissible color variation in the color appearance of stained…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Suman Mahapatra , Pradipta Maji

In the field of computational pathology, deep learning algorithms have made significant progress in tasks such as nuclei segmentation and classification. However, the potential of these advanced methods is limited by the lack of available…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Hyun-Jic Oh , Won-Ki Jeong

Weakly supervised segmentation methods can delineate thyroid nodules in ultrasound images efficiently using training data with coarse labels, but suffer from: 1) low-confidence pseudo-labels that follow topological priors, introducing…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Jianning Chi , Zelan Li , Geng Lin , MingYang Sun , Xiaosheng Yu

Deep Learning based models are currently dominating most state-of-the-art solutions for disease prediction. Existing works employ RNNs along with multiple levels of attention mechanisms to provide interpretability. These deep learning…

Machine Learning · Statistics 2022-06-01 Subhadip Maji , Raghav Bali , Sree Harsha Ankem , Kishore V Ayyadevara

Nucleus segmentation and classification are the prerequisites in the workflow of digital pathology processing. However, it is very challenging due to its high-level heterogeneity and wide variations. This work proposes a deep neural network…

Image and Video Processing · Electrical Eng. & Systems 2022-12-07 Sen Yang , Jinxi Xiang , Xiyue Wang

Machine learning-based intrusion detection requires complex models to capture patterns in high-dimensional, noisy, and class-imbalanced raw network traffic, yet deploying such models remains impractical on resource-constrained devices with…

Explaining recommendations enables users to understand whether recommended items are relevant to their needs and has been shown to increase their trust in the system. More generally, if designing explainable machine learning models is key…

Machine Learning · Computer Science 2020-08-27 Darius Afchar , Romain Hennequin

Existing weakly-supervised semantic segmentation methods using image-level annotations typically rely on initial responses to locate object regions. However, such response maps generated by the classification network usually focus on…

Computer Vision and Pattern Recognition · Computer Science 2020-08-05 Yu-Ting Chang , Qiaosong Wang , Wei-Chih Hung , Robinson Piramuthu , Yi-Hsuan Tsai , Ming-Hsuan Yang

To address the increasing need for efficient and accurate content moderation, we propose an efficient and lightweight deep classification ensemble structure. Our approach is based on a combination of simple visual features, designed for…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Mohammad Hosseini , Mahmudul Hasan

This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Yuxin Cui , Guiying Zhang , Zhonghao Liu , Zheng Xiong , Jianjun Hu

Nucleus detection in histopathology is pivotal for a wide range of clinical applications. Existing approaches either regress nuclear proxy maps that require complex post-processing, or employ dense anchors or queries that introduce severe…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Zhongyi Shui , Honglin Li , Xiaozhong Ji , Ye Zhang , Zijiang Yang , Chenglu Zhu , Yuxuan Sun , Kai Yao , Conghui He , Cheng Tan

Accurate nuclei segmentation is an essential foundation for various applications in computational pathology, including cancer diagnosis and treatment planning. Even slight variations in nuclei representations can significantly impact these…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Zunaira Rauf , Abdul Rehman Khan , Asifullah Khan

Weakly supervised learning of object detection is an important problem in image understanding that still does not have a satisfactory solution. In this paper, we address this problem by exploiting the power of deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2016-12-20 Hakan Bilen , Andrea Vedaldi

Accurate segmenting nuclei instances is a crucial step in computer-aided image analysis to extract rich features for cellular estimation and following diagnosis as well as treatment. While it still remains challenging because the wide…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Yanning Zhou , Omer Fahri Onder , Qi Dou , Efstratios Tsougenis , Hao Chen , Pheng-Ann Heng

Recent successes of Deep Neural Networks (DNNs) in a variety of research tasks, however, heavily rely on the large amounts of labeled samples. This may require considerable annotation cost in real-world applications. Fortunately, active…

Machine Learning · Computer Science 2020-09-08 Qiang Liu , Zhaocheng Liu , Xiaofang Zhu , Yeliang Xiu

Histopathology image analysis is critical yet challenged by the demand of segmenting tissue regions and nuclei instances for tumor microenvironment and cellular morphology analysis. Existing studies focused on tissue semantic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Qing Xu , Wenting Duan , Zhen Chen

This work proposes a novel approach beyond supervised learning for effective pathological image analysis, addressing the challenge of limited robust labeled data. Pathological diagnosis of diseases like cancer has conventionally relied on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Joonhyeon Song , Seohwan Yun , Seongho Yoon , Joohyeok Kim , Sangmin Lee

Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

We propose a lightly-supervised approach for information extraction, in particular named entity classification, which combines the benefits of traditional bootstrapping, i.e., use of limited annotations and interpretability of extraction…

Computation and Language · Computer Science 2018-05-30 Marco A. Valenzuela-Escárcega , Ajay Nagesh , Mihai Surdeanu