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Related papers: Light-Field Microscopy for optical imaging of neur…

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Neural fields, a category of neural networks trained to represent high-frequency signals, have gained significant attention in recent years due to their impressive performance in modeling complex 3D data, such as signed distance (SDFs) or…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Marko Mihajlovic , Sergey Prokudin , Marc Pollefeys , Siyu Tang

We report on the 3-dimensional imaging of biological cells including living neurons by a recently developed fibered interferometric Scanning Optical Microscope. The topography and surface structure of mouse fibroblasts and hippocampal…

A major tenet in theoretical neuroscience is that cognitive and behavioral processes are ultimately implemented in terms of the neural system dynamics. Accordingly, a major aim for the analysis of neurophysiological measurements should lie…

Machine Learning · Computer Science 2020-07-01 Georgia Koppe , Hazem Toutounji , Peter Kirsch , Stefanie Lis , Daniel Durstewitz

Multimode fibers (MMFs) can transmit multiple guided modes simultaneously, making them a promising platform for high-resolution biomedical imaging, endoscopy and high-bandwidth optical communication. However, their complex modal behavior,…

Optics · Physics 2026-05-28 Dvir Marsh , Lior Fridman , Stav Lotan , Amit Kam , Shie Mannor , Guy Bartal

Computational Cannula Microscopy (CCM) is a high-resolution widefield fluorescence imaging approach deep inside tissue, which is minimally invasive. Rather than using conventional lenses, a surgical cannula acts as a lightpipe for both…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ruipeng Guo , Zhimeng Pan , Andrew Taibi , Jason Shepherd , Rajesh Menon

We present a deep learning driven computational approach to overcome the limitations of self-interference digital holography that imposed by inferior axial imaging performances. We demonstrate a 3D deep neural network model can…

Optical approaches have made great strides towards the goal of high-speed, energy-efficient computing necessary for modern deep learning and AI applications. Read-in and read-out of data, however, limit the overall performance of existing…

Emerging Technologies · Computer Science 2024-02-06 Alexander Song , Sai Nikhilesh Murty Kottapalli , Rahul Goyal , Bernhard Schölkopf , Peer Fischer

Light-field fluorescence microscopy (LFM) is a powerful elegant compact method for long-term high-speed imaging of complex biological systems, such as neuron activities and rapid movements of organelles. LFM experiments typically generate…

Image and Video Processing · Electrical Eng. & Systems 2023-10-17 Changqing Su , Zihan Lin , You Zhou , Shuai Wang , Yuhan Gao , Chenggang Yan , Bo Xiong

Relying on either deep models or physical models are two mainstream approaches for solving inverse sample reconstruction problems in programmable illumination computational microscopy. Solutions based on physical models possess strong…

Image and Video Processing · Electrical Eng. & Systems 2024-03-21 Ruiqing Sun , Delong Yang , Shaohui Zhang , Qun Hao

This paper introduces a new method of data-driven microscope design for virtual fluorescence microscopy. Our results show that by including a model of illumination within the first layers of a deep convolutional neural network, it is…

Image and Video Processing · Electrical Eng. & Systems 2020-04-23 Colin L. Cooke , Fanjie Kong , Amey Chaware , Kevin C. Zhou , Kanghyun Kim , Rong Xu , D. Michael Ando , Samuel J. Yang , Pavan Chandra Konda , Roarke Horstmeyer

The formation of organized optical states in multidimensional systems is crucial for understanding light-matter interaction and advancing light-shaping technologies. Here, we report the observation of a self-localized, ultrafast pencil beam…

Computational neuroimaging involves analyzing brain images or signals to provide mechanistic insights and predictive tools for human cognition and behavior. While diffusion models have shown stability and high-quality generation in natural…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Haokai Zhao , Haowei Lou , Lina Yao , Wei Peng , Ehsan Adeli , Kilian M Pohl , Yu Zhang

This paper introduces a novel framework for image quality transfer based on conditional flow matching (CFM). Unlike conventional generative models that rely on iterative sampling or adversarial objectives, CFM learns a continuous flow…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Huu Tien Nguyen , Ahmed Karam Eldaly

Morphology based analysis of cell types has been an area of great interest to the neuroscience community for several decades. Recently, high resolution electron microscopy (EM) datasets of the mouse brain have opened up opportunities for…

Dynamic imaging is essential for analyzing various biological systems and behaviors but faces two main challenges: data incompleteness and computational burden. For many imaging systems, high frame rates and short acquisition times require…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Luke Lozenski , Mark A. Anastasio , Umberto Villa

The development of deep neural networks is witnessing fast growth in network size, which requires novel hardware computing platforms with large bandwidth and low energy consumption. Optical computing has been a potential candidate for…

Neuromorphic computing-modelled after the functionality and efficiency of biological neural systems-offers promising new directions for advancing artificial intelligence and computational models. Photonic techniques for neuromorphic…

Functional brain imaging allows measuring dynamic functionality in all brain regions. It is broadly used in clinical cognitive neuroscience as, well as in research. It will allow the observation of neural activities in the brain…

Medical Physics · Physics 2016-04-01 Saman Sarraf , Jian Sun

Current medical image segmentation approaches have limitations in deeply exploring multi-scale information and effectively combining local detail textures with global contextual semantic information. This results in over-segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-08 Zhenkun Lu , Chaoyin She , Wei Wang , Qinghua Huang

Advancements in high-throughput biomedical applications require real-time, large field-of-view (FOV) imaging. While current 2D lens-free imaging (LFI) systems improve FOV, they are often hindered by time-consuming multi-position…

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