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In this paper, we aimed at reviewing several different approaches present today in the search for more accurate diagnostic and treatment management in mental healthcare. Our focus is on mood disorders, and in particular on the major…

Neurons and Cognition · Quantitative Biology 2019-03-28 Milena Cukic Radenkovic

Depression disorder is a serious health condition that has affected the lives of millions of people around the world. Diagnosis of depression is a challenging practice that relies heavily on subjective studies and, in most cases, suffers…

Signal Processing · Electrical Eng. & Systems 2025-03-26 Amir Nassibi , Christos Papavassiliou , Ildar Rakhmatulin , Danilo Mandic , S. Farokh Atashzar

Depression is a common psychiatric disorder, which causes significant patient distress. Bipolar disorder is characterized by mood fluctuations between depression and mania. Unipolar and bipolar depression can be easily confused because of…

Image and Video Processing · Electrical Eng. & Systems 2019-09-02 Marie Zelenina , Diana Prata

Depression is a common mental illness that has to be detected and treated at an early stage to avoid serious consequences. There are many methods and modalities for detecting depression that involves physical examination of the individual.…

Artificial Intelligence · Computer Science 2022-02-08 Kayalvizhi S , Thenmozhi D

In current medical practice, patients undergoing depression treatment must wait four to six weeks before a clinician can assess medication response due to the delayed noticeable effects of antidepressants. Identification of a treatment…

Machine Learning · Computer Science 2025-01-09 Melanija Kraljevska , Katerina Hlavackova-Schindler , Lukas Miklautz , Claudia Plant

This study investigates the detection and classification of depressive and non-depressive states using deep learning approaches. Depression is a prevalent mental health disorder that substantially affects quality of life, and early…

Quantitative Methods · Quantitative Biology 2026-01-19 Mohammad Reza Yousefi , Hajar Ismail Al-Tamimi , Amin Dehghani

In universal environment, a patient-friendly inexpensive method is needed to realize the early diagnosis of depression, which is believed to be an effective way to reduce the mortality of depression. The purpose of this study is only to…

Signal Processing · Electrical Eng. & Systems 2020-02-28 Qiuxia Shi , Ang Liu , Rongyan Chen , Jian Shen , Qinglin Zhao , Bin Hu

According to the World Health Organization, the number of mental disorder patients, especially depression patients, has grown rapidly and become a leading contributor to the global burden of disease. However, the present common practice of…

Recurrent major mood episodes and subsyndromal mood instability cause substantial disability in patients with bipolar disorder. Early identification of mood episodes enabling timely mood stabilisation is an important clinical goal. Recent…

Machine Learning · Statistics 2017-08-04 Andrey Kormilitzin , Kate E. A. Saunders , Paul J. Harrison , John R. Geddes , Terry Lyons

Automated methods have been widely used to identify and analyze mental health conditions (e.g., depression) from various sources of information, including social media. Yet, deployment of such models in real-world healthcare applications…

Computation and Language · Computer Science 2022-04-25 Thong Nguyen , Andrew Yates , Ayah Zirikly , Bart Desmet , Arman Cohan

Background and Objective: The connection between depression and autonomous nervous system (ANS) is well documented in scientific literature. Heart rate variability (HRV) is a rich source of information for studying the dynamics of this…

Neurons and Cognition · Quantitative Biology 2021-10-19 Milena Čukić , Danka Savić , Julia Sidorova

The present literature about possible mechanisms behind the effectivity of noninvasive electromagnetic stimulation in major depressive disorder (MDD) is not very rich. Despite extensive research in applications for clinical practice, the…

Neurons and Cognition · Quantitative Biology 2019-12-19 Milena Cukic

In this paper, we aimed at reviewing present literature on employing nonlinear analysis in combination with machine learning methods, in depression detection or prediction task. We are focusing on an affordable data-driven approach,…

Signal Processing · Electrical Eng. & Systems 2019-09-10 Milena Čukić Radenković , Victoria Lopez Lopez

Electroencephalogram (EEG) provides noninvasive measures of brain activity and is found to be valuable for diagnosis of some chronic disorders. Specifically, pre-treatment EEG signals in alpha and theta frequency bands have demonstrated…

Applications · Statistics 2023-05-24 Bin Yang , Xingche Guo , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

Depression is the leading cause of disability worldwide. Initial efforts to detect depression signals from social media posts have shown promising results. Given the high internal validity, results from such analyses are potentially…

Social and Information Networks · Computer Science 2020-06-16 Lucia Lushi Chen , Walid Magdy , Heather Whalley , Maria Wolters

The COVID-19 pandemic has forced many people to limit their social activities, which has resulted in a rise in mental illnesses, particularly depression. To diagnose these illnesses with accuracy and speed, and prevent severe outcomes such…

Machine Learning · Computer Science 2023-11-14 Hossein Simchi , Samira Tajik

Depression is a widespread mental health disorder, yet its automatic detection remains challenging. Prior work has explored unimodal and multimodal approaches, with multimodal systems showing promise by leveraging complementary signals.…

Artificial Intelligence · Computer Science 2026-03-24 Annisaa Fitri Nurfidausi , Eleonora Mancini , Paolo Torroni

This review provides a dynamical systems perspective on psychiatric symptoms and disease, and discusses its potential implications for diagnosis, prognosis, and treatment. After a brief introduction into the theory of dynamical systems, we…

Neurons and Cognition · Quantitative Biology 2018-09-18 Daniel Durstewitz , Quentin J. M. Huys , Georgia Koppe

This study integrates causal inference, graph analysis, temporal complexity measures, and machine learning to examine whether individual symptom trajectories can reveal meaningful diagnostic patterns. Testing on a longitudinal dataset of…

Applications · Statistics 2025-07-22 Eleonora Vitanza , Pietro DeLellis , Chiara Mocenni , Manuel Ruiz Marin

The nature of mental illness remains a conundrum. Traditional disease categories are increasingly suspected to mis-represent the causes underlying mental disturbance. Yet, psychiatrists and investigators now have an unprecedented…

Applications · Statistics 2017-05-31 Danilo Bzdok , Andreas Meyer-Lindenberg
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