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Relation extraction in the biomedical domain is challenging due to the lack of labeled data and high annotation costs, needing domain experts. Distant supervision is commonly used to tackle the scarcity of annotated data by automatically…

Computation and Language · Computer Science 2022-09-14 Saadullah Amin , Pasquale Minervini , David Chang , Pontus Stenetorp , Günter Neumann

Multiple Instance Learning is the predominant method for Whole Slide Image classification in digital pathology, enabling the use of slide-level labels to supervise model training. Although MIL eliminates the tedious fine-grained annotation…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Chen Shu , Boyu Fu , Yiman Li , Ting Yin , Wenchuan Zhang , Jie Chen , Yuhao Yi , Hong Bu

With recent advances in distantly supervised (DS) relation extraction (RE), considerable attention is attracted to leverage multi-instance learning (MIL) to distill high-quality supervision from the noisy DS. Here, we go beyond label noise…

Computation and Language · Computer Science 2021-06-22 Tao Chen , Haochen Shi , Liyuan Liu , Siliang Tang , Jian Shao , Zhigang Chen , Yueting Zhuang

Multiple Instance Learning (MIL) is widely used in medical imaging classification to reduce the labeling effort. While only bag labels are available for training, one typically seeks predictions at both bag and instance levels…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Francisco M. Castro-Macías , Pablo Morales-Álvarez , Yunan Wu , Rafael Molina , Aggelos K. Katsaggelos

Relation extraction is a fundamental problem in natural language processing. Most existing models are defined for relation extraction in the general domain. However, their performance on specific domains (e.g., biomedicine) is yet unclear.…

Computation and Language · Computer Science 2021-12-14 Yongkang Li

To minimize the accelerating amount of time invested in the biomedical literature search, numerous approaches for automated knowledge extraction have been proposed. Relation extraction is one such task where semantic relations between the…

Computation and Language · Computer Science 2020-09-22 Shweta Yadav , Srivatsa Ramesh , Sriparna Saha , Asif Ekbal

A growing number of applications, e.g. video surveillance and medical image analysis, require training recognition systems from large amounts of weakly annotated data while some targeted interactions with a domain expert are allowed to…

Computer Vision and Pattern Recognition · Computer Science 2022-05-10 Marc-André Carbonneau , Eric Granger , Ghyslain Gagnon

The journey of reducing noise from distant supervision (DS) generated training data has been started since the DS was first introduced into the relation extraction (RE) task. For the past decade, researchers apply the multi-instance…

Computation and Language · Computer Science 2021-06-22 Tao Chen , Haizhou Shi , Siliang Tang , Zhigang Chen , Fei Wu , Yueting Zhuang

Multiple instance learning (MIL) is a promising approach for weakly supervised classification in pathology using whole slide images (WSIs). However, conventional MIL methods such as Attention-Based Deep Multiple Instance Learning (ABMIL)…

Image and Video Processing · Electrical Eng. & Systems 2025-04-28 Hassan Keshvarikhojasteh , Mihail Tifrea , Sibylle Hess , Josien P. W. Pluim , Mitko Veta

Existing in-context learning (ICL) methods for relation extraction (RE) often prioritize language similarity over structural similarity, which can lead to overlooking entity relationships. To address this, we propose an AMR-enhanced…

Computation and Language · Computer Science 2025-04-28 Peitao Han , Lis Kanashiro Pereira , Fei Cheng , Wan Jou She , Eiji Aramaki

Knowledge base provides a potential way to improve the intelligence of information retrieval (IR) systems, for that knowledge base has numerous relations between entities which can help the IR systems to conduct inference from one entity to…

Computation and Language · Computer Science 2019-07-29 Hai Ye , Zhunchen Luo

Extracting biomedical relations from large corpora of scientific documents is a challenging natural language processing task. Existing approaches usually focus on identifying a relation either in a single sentence (mention-level) or across…

Computation and Language · Computer Science 2020-11-23 Harshil Shah , Julien Fauqueur

Traditional supervised learning tasks require a label for every instance in the training set, but in many real-world applications, labels are only available for collections (bags) of instances. This problem setting, known as multiple…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Georg Wölflein , Lucie Charlotte Magister , Pietro Liò , David J. Harrison , Ognjen Arandjelović

Fact triples are a common form of structured knowledge used within the biomedical domain. As the amount of unstructured scientific texts continues to grow, manual annotation of these texts for the task of relation extraction becomes…

Computation and Language · Computer Science 2020-05-27 Saadullah Amin , Katherine Ann Dunfield , Anna Vechkaeva , Günter Neumann

Single-cell datasets often lack individual cell labels, making it challenging to identify cells associated with disease. To address this, we introduce Mixture Modeling for Multiple Instance Learning (MMIL), an expectation maximization…

Quantitative Methods · Quantitative Biology 2024-06-13 Erin Craig , Timothy Keyes , Jolanda Sarno , Maxim Zaslavsky , Garry Nolan , Kara Davis , Trevor Hastie , Robert Tibshirani

Segmenting tumors in histological images is vital for cancer diagnosis. While fully supervised models excel with pixel-level annotations, creating such annotations is labor-intensive and costly. Accurate histopathology image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Yinsheng He , Xingyu Li , Roger J. Zemp

Document-Level Biomedical Relation Extraction (Bio-RE) aims to identify relations between biomedical entities within extensive texts, serving as a crucial subfield of biomedical text mining. Existing Bio-RE methods struggle with…

Computation and Language · Computer Science 2025-01-10 Yufei Shang , Yanrong Guo , Shijie Hao , Richang Hong

Existing neural relation extraction (NRE) models rely on distant supervision and suffer from wrong labeling problems. In this paper, we propose a novel adversarial training mechanism over instances for relation extraction to alleviate the…

Computation and Language · Computer Science 2018-05-29 Xu Han , Zhiyuan Liu , Maosong Sun

Understanding the meaning of text often involves reasoning about entities and their relationships. This requires identifying textual mentions of entities, linking them to a canonical concept, and discerning their relationships. These tasks…

Computation and Language · Computer Science 2019-12-04 Trapit Bansal , Pat Verga , Neha Choudhary , Andrew McCallum

Scarcity of labeled data is one of the most frequent problems faced in machine learning. This is particularly true in relation extraction in text mining, where large corpora of texts exists in many application domains, while labeling of…

Machine Learning · Computer Science 2018-07-13 Linara Adilova , Sven Giesselbach , Stefan Rüping
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