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Multiple sequence alignment (MSA) has been one of the most important problems in bioinformatics for more decades and it is still heavily examined by many mathematicians and biologists. However, mostly because of the practical motivation of…

Quantitative Methods · Quantitative Biology 2015-11-17 Kristóf Takács

Longest common subsequence (LCS) is one of the most fundamental problems in combinatorial optimization. Apart from theoretical importance, LCS has enormous applications in bioinformatics, revision control systems, and data comparison…

Data Structures and Algorithms · Computer Science 2020-03-17 MohammadTaghi Hajiaghayi , Masoud Seddighin , Saeed Seddighin , Xiaorui Sun

Finding an Approximate Longest Common Substring (ALCS) within a given set $S=\{s_1,s_2,\ldots,s_m\}$ of $m \ge 2$ strings is a key problem in computational biology, such as identifying related mutations across multiple genetic sequences. We…

Data Structures and Algorithms · Computer Science 2025-09-22 Hamed Hasibi , Neerja Mhaskar , W. F. Smyth

The Longest Common Subsequence (LCS) is a fundamental string similarity measure, and computing the LCS of two strings is a classic algorithms question. A textbook dynamic programming algorithm gives an exact algorithm in quadratic time, and…

Data Structures and Algorithms · Computer Science 2023-02-13 Xiaoyu He , Ray Li

This paper investigates the approximability of the Longest Common Subsequence (LCS) problem. The fastest algorithm for solving the LCS problem exactly runs in essentially quadratic time in the length of the input, and it is known that under…

Data Structures and Algorithms · Computer Science 2021-05-10 Shyan Akmal , Virginia Vassilevska Williams

Given a pair of strings, the problems of computing their Longest Common Subsequence and Edit Distance have been extensively studied for decades. For exact algorithms, LCS and Edit Distance (with character insertions and deletions) are…

Data Structures and Algorithms · Computer Science 2019-04-12 Aviad Rubinstein , Zhao Song

We present novel randomized approximation schemes for the Edit Distance (ED) problem and the Longest Common Subsequence (LCS) problem that, for any constant $\epsilon>0$, compute a $(1+\epsilon)$-approximation for ED and a…

Data Structures and Algorithms · Computer Science 2026-04-01 Xiao Mao , Aviad Rubinstein

Finding the longest common subsequence in $k$-length substrings (LCS$k$) is a recently proposed problem motivated by computational biology. This is a generalization of the well-known LCS problem in which matching symbols from two sequences…

Data Structures and Algorithms · Computer Science 2013-11-20 Sebastian Deorowicz , Szymon Grabowski

Longest common subsequence ($\mathsf{LCS}$) is a classic and central problem in combinatorial optimization. While $\mathsf{LCS}$ admits a quadratic time solution, recent evidence suggests that solving the problem may be impossible in truly…

Data Structures and Algorithms · Computer Science 2021-11-23 Aviad Rubinstein , Saeed Seddighin , Zhao Song , Xiaorui Sun

Let $A$ and $B$ be two number sequences of length $n$ and $m$, respectively, where $m\le n$. Given a positive number $\delta$, a common almost increasing sequence $s_1\ldots s_k$ is a common subsequence for both $A$ and $B$ such that for…

Data Structures and Algorithms · Computer Science 2025-05-08 Md Tanzeem Rahat , Md. Manzurul Hasan , Debajyoti Mondal

Calculating the length of a longest common subsequence (LCS) of two strings $A$ and $B$ of length $n$ and $m$ is a classic research topic, with many worst-case oriented results known. We present two algorithms for LCS length calculation…

Data Structures and Algorithms · Computer Science 2014-05-22 Szymon Grabowski

We provide a deterministic algorithm that outputs an $O(n^{3/4} \log n)$-approximation for the Longest Common Subsequence (LCS) of two input sequences of length $n$ in near-linear time. This is the first deterministic approximation…

Data Structures and Algorithms · Computer Science 2025-07-31 Itai Boneh , Shay Golan , Matan Kraus

In this paper we define a new problem, motivated by computational biology, $LCSk$ aiming at finding the maximal number of $k$ length $substrings$, matching in both input strings while preserving their order of appearance. The traditional…

Data Structures and Algorithms · Computer Science 2014-02-11 Gary Benson , Avivit Levy , Riva Shalom

The Longest Common Subsequence (LCS) problem is a fundamental problem of sequence comparison. A natural approximation to this problem is a model in which every pairs of letters of two ``sequences'' are matched independently of the other…

Disordered Systems and Neural Networks · Physics 2016-08-31 J. Boutet de Monvel

We revisit the classic combinatorial pattern matching problem of finding a longest common subsequence (LCS). For strings $x$ and $y$ of length $n$, a textbook algorithm solves LCS in time $O(n^2)$, but although much effort has been spent,…

Computational Complexity · Computer Science 2018-03-05 Karl Bringmann , Marvin Künnemann

The Longest Common Subsequence (LCS) of two strings is a fundamental string similarity measure with a classical dynamic programming solution taking quadratic time. Despite significant efforts, little progress was made in improving the…

Data Structures and Algorithms · Computer Science 2021-12-17 Negev Shekel Nosatzki

Two important similarity measures between sequences are the longest common subsequence (LCS) and the dynamic time warping distance (DTWD). The computations of these measures for two given sequences are central tasks in a variety of…

Computational Complexity · Computer Science 2015-02-02 Amir Abboud , Arturs Backurs , Virginia Vassilevska Williams

The problem of approximate string matching is important in many different areas such as computational biology, text processing and pattern recognition. A great effort has been made to design efficient algorithms addressing several variants…

Data Structures and Algorithms · Computer Science 2008-07-29 Dimitris Papamichail , Georgios Papamichail

The {\em longest common subsequence (LCS)} problem is a classic and well-studied problem in computer science. LCS is a central problem in stringology and finds broad applications in text compression, error-detecting codes and biological…

Data Structures and Algorithms · Computer Science 2010-04-20 Shihabur Rahman Chowdhury , Masud Hasan , Sumaiya Iqbal , M. Sohel Rahman

We consider the classic problem of computing the Longest Common Subsequence (LCS) of two strings of length $n$. While a simple quadratic algorithm has been known for the problem for more than 40 years, no faster algorithm has been found…

Data Structures and Algorithms · Computer Science 2021-06-16 Karl Bringmann , Vincent Cohen-Addad , Debarati Das
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