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A bioinformatics platform is introduced aimed at identifying models of disease-specific pathways, as well as a set of network measures that can quantify changes in terms of global structure or single link disruptions.The approach integrates…

Molecular Networks · Quantitative Biology 2012-01-17 A. Barla , S. Riccadonna , S. Masecchia , M. Squillario , M. Filosi , G. Jurman , C. Furlanello

The increasing integration of Artificial Intelligence across multiple industry sectors necessitates robust mechanisms for ensuring transparency, trust, and auditability of its development and deployment. This topic is particularly important…

Cryptography and Security · Computer Science 2025-03-31 Kar Balan , Robert Learney , Tim Wood

With the increasing amount of data and use of computation in science, software has become an important component in many different domains. Computing is now being used more often and in more aspects of scientific work including data…

Software Engineering · Computer Science 2013-12-17 David Koop , Juliana Freire , Claudio T. Silva

Biomedical research increasingly relies on heterogeneous, high-dimensional datasets, yet effective visualization remains hindered by fragmented code resources, steep programming barriers, and limited domain-specific guidance. Bizard is an…

As the Lakehouse architecture becomes more widespread, ensuring the reproducibility of data workloads over data lakes emerges as a crucial concern for data engineers. However, achieving reproducibility remains challenging. The size of data…

Databases · Computer Science 2024-04-23 Jacopo Tagliabue , Ciro Greco

Open source software development, particularly within institutions such as universities and research laboratories, is often decentralized and difficult to track. Although academic teams produce many impactful scientific tools, their…

Software Engineering · Computer Science 2026-02-27 Juanita Gomez , Emily Lovell , Stephanie Lieggi , Alvaro A. Cardenas , James Davis

Programming Language Processing (PLP) using machine learning has made vast improvements in the past few years. Increasingly more people are interested in exploring this promising field. However, it is challenging for new researchers and…

Machine Learning · Computer Science 2023-06-19 Patrick Flynn , Tristan Vanderbruggen , Chunhua Liao , Pei-Hung Lin , Murali Emani , Xipeng Shen

Developing software to undertake complex, compute-intensive scientific processes requires a challenging combination of both specialist domain knowledge and software development skills to convert this knowledge into efficient code. As…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-09-05 Jeremy Cohen , Chris Cantwell , Neil Chue Hong , David Moxey , Malcolm Illingworth , Andrew Turner , John Darlington , Spencer Sherwin

PaPy, which stands for parallel pipelines in Python, is a highly flexible framework that enables the construction of robust, scalable workflows for either generating or processing voluminous datasets. A workflow is created from user-written…

Programming Languages · Computer Science 2014-07-17 Marcin Cieslik , Cameron Mura

Scientific workflow management systems offer features for composing complex computational pipelines from modular building blocks, for executing the resulting automated workflows, and for recording the provenance of data products resulting…

DAPHNE is a new open-source software infrastructure designed to address the increasing demands of integrated data analysis (IDA) pipelines, comprising data management (DM), high performance computing (HPC), and machine learning (ML)…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-08-04 Ahmed Eleliemy , Florina M. Ciorba

Developing complex biomolecular workflows is not always straightforward. It requires tedious developments to enable the interoperability between the different biomolecular simulation and analysis tools. Moreover, the need to execute the…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-12-20 Jorge Ejarque , Pau Andrio , Adam Hospital , Javier Conejero , Daniele Lezzi , Josep LL. Gelpi , Rosa M. Badia

Study reproducibility is essential to corroborate, build on, and learn from the results of scientific research but is notoriously challenging in bioinformatics, which often involves large data sets and complex analytic workflows involving…

Quantitative Methods · Quantitative Biology 2023-05-22 Christopher R. Keefe , Matthew R. Dillon , Chloe Herman , Mary Jewell , Colin V. Wood , Evan Bolyen , J. Gregory Caporaso

Machine Learning (ML) is increasingly used to automate impactful decisions, which leads to concerns regarding their correctness, reliability, and fairness. We envision highly-automated software platforms to assist data scientists with…

Databases · Computer Science 2024-09-04 Stefan Grafberger

In research labs, there is often a need to customise software at every step in a given bioinformatics workflow, but traditionally it has been difficult to obtain both a high degree of customisability and good performance.…

Software Engineering · Computer Science 2012-08-23 Gabriel Keeble-Gagnère , Johan Nyström-Persson , Matthew Bellgard , Kenji Mizuguchi

Motivation: Bioinformatics software often lacks graphical user interfaces (GUIs), which can limit its adoption by non-technical members of the scientific community. Web interfaces are a common alternative for building cross-platform GUIs,…

Software Engineering · Computer Science 2020-02-21 Andres Veidenberg , Ari Löytynoja

Next generation of embedded Information and Communication Technology (ICT) systems are collaborative systems able to perform autonomous tasks. The remarkable expansion of the embedded ICT market, together with the rise and breakthroughs of…

With constant improvements of quantum hardware and quantum algorithms, quantum advantage comes within reach. Parallel to the development of the computer at the end of the twentieth century, quantum software development will now also rapidly…

Artificial intelligence (AI) techniques are widely applied in the life sciences. However, applying innovative AI techniques to understand and deconvolute biological complexity is hindered by the learning curve for life science scientists to…

Artificial Intelligence · Computer Science 2024-03-28 Nisha Pillai , Athish Ram Das , Moses Ayoola , Ganga Gireesan , Bindu Nanduri , Mahalingam Ramkumar

This paper presents the cognitive module of the cognitive architecture for artificial intelligence (CAAI) in cyber-physical production systems (CPPS). The goal of this architecture is to reduce the implementation effort of artificial…

Artificial Intelligence · Computer Science 2021-06-09 Jan Strohschein , Andreas Fischbach , Andreas Bunte , Heide Faeskorn-Woyke , Natalia Moriz , Thomas Bartz-Beielstein